This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Aguirre L, Portillo MP, Hijona E, Bujanda L. Effects of resveratrol and other polyphenols in hepatic steatosis. World J Gastroenterol. 2014;20:7366–7380. doi.org/10.3748/wjg.v20.i23.7366.AguirreLPortilloMPHijonaEBujandaLEffects of resveratrol and other polyphenols in hepatic steatosis20142073667380doi.org/10.3748/wjg.v20.i23.7366.Search in Google Scholar
Ajith TA. Role of mitochondria and mitochondria-targeted agents in non-alcoholic fatty liver disease. Clin Exp Pharmacol Physiol. 2018;45:413–421. doi.org/10.1111/1440-1681.12886.AjithTARole of mitochondria and mitochondria-targeted agents in non-alcoholic fatty liver disease201845413421doi.org/10.1111/1440-1681.12886.Search in Google Scholar
Akerman KE, Wikström MK. Safranine as a probe of the mitochondrial membrane potential. FEBS Lett. 1976;68:191–197. https://doi.org/10.1016/0014-5793(76)80434-6.AkermanKEWikströmMKSafranine as a probe of the mitochondrial membrane potential197668191197https://doi.org/10.1016/0014-5793(76)80434-6.Search in Google Scholar
Al-Dosari MS. Red cabbage (Brassica oleracea L.) mediates redox-sensitive amelioration of dyslipidemia and hepatic injury induced by exogenous cholesterol administration. Am J Chin Med. 2014;42:189–206. doi.org/10.1142/S0192415X1450013X.Al-DosariMSRed cabbage (Brassica oleracea L.) mediates redox-sensitive amelioration of dyslipidemia and hepatic injury induced by exogenous cholesterol administration201442189206doi.org/10.1142/S0192415X1450013X.Search in Google Scholar
Aza-González C, Ochoa-Alejo N. Characterization of anthocyanins from fruits of two Mexican chili peppers (Capsicum annuum L.). J Mex Chem Soc. 2012;56:149–151. doi.org/10.29356/jmcs.v56i2.313.Aza-GonzálezCOchoa-AlejoNCharacterization of anthocyanins from fruits of two Mexican chili peppers (Capsicum annuum L.)201256149151doi.org/10.29356/jmcs.v56i2.313.Search in Google Scholar
Bartlett PJ, Antony AN, Agarwal A, et al. Chronic alcohol feeding potentiates hormone-induced calcium signalling in hepatocytes. J Physiol. 2017;595:3143–3164. doi.org/10.1113/JP273891.BartlettPJAntonyANAgarwalAChronic alcohol feeding potentiates hormone-induced calcium signalling in hepatocytes201759531433164doi.org/10.1113/JP273891.Search in Google Scholar
Bendokas V, Skemiene K, Trumbeckaite S, et al. Anthocyanins: From plant pigments to health benefits at mitochondrial level. Crit Rev Food Sci Nutr. 2020;60:3352–3365. doi.org/10.1080/10408398.2019.1687421.BendokasVSkemieneKTrumbeckaiteSAnthocyanins: From plant pigments to health benefits at mitochondrial level20206033523365doi.org/10.1080/10408398.2019.1687421.Search in Google Scholar
Bendokas V, Stanys V, Mažeikienė I, Trumbeckaite S, Baniene R, Liobikas J. Anthocyanins: From the field to the antioxidants in the body. Antioxidants (Basel). 2020;9:819. doi.org/10.3390/antiox9090819.BendokasVStanysVMažeikienėITrumbeckaiteSBanieneRLiobikasJAnthocyanins: From the field to the antioxidants in the body20209819doi.org/10.3390/antiox9090819.Search in Google Scholar
Blaser H, Dostert C, Mak TW, Brenner D. TNF and ROS crosstalk in inflammation. Trends Cell Biol. 2016;26:249–261. doi.org/10.1016/j.tcb.2015.12.002.BlaserHDostertCMakTWBrennerDTNF and ROS crosstalk in inflammation201626249261doi.org/10.1016/j.tcb.2015.12.002.Search in Google Scholar
Buko V, Kuzmitskaya I, Kirko S, et al. Betulin attenuated liver damage by prevention of hepatic mitochondrial dysfunction in rats with alcoholic steatohepatitis. Physiol Int. 2019;106:323–334. doi.org/10.1556/2060.106.2019.26.BukoVKuzmitskayaIKirkoSBetulin attenuated liver damage by prevention of hepatic mitochondrial dysfunction in rats with alcoholic steatohepatitis2019106323334doi.org/10.1556/2060.106.2019.26.Search in Google Scholar
Buko V, Zavodnik I, Kanuka O, et al. Antidiabetic effects and erythrocyte stabilization by red cabbage extract in streptozotocin-treated rats. Food Funct. 2018;9:1850–1863. doi.org/10.1039/c7fo01823a.BukoVZavodnikIKanukaOAntidiabetic effects and erythrocyte stabilization by red cabbage extract in streptozotocin-treated rats2018918501863doi.org/10.1039/c7fo01823a.Search in Google Scholar
Chacko BK, Srivastava A, Johnson MS, et al. Mitochondria-targeted ubiquinone (MitoQ) decreases ethanol-dependent micro and macro hepatosteatosis. Hepatol. 2011;54:153–163. doi.org/10.1002/hep.24377.ChackoBKSrivastavaAJohnsonMSMitochondria-targeted ubiquinone (MitoQ) decreases ethanol-dependent micro and macro hepatosteatosis201154153163doi.org/10.1002/hep.24377.Search in Google Scholar
de Ferrars RM, Czank C, Zhang Q, et al. The pharmacokinetics of anthocyanins and their metabolites in humans. Br J Pharmacol. 2014;171:3268–3282. doi.org/10.1111/bph.12676.de FerrarsRMCzankCZhangQThe pharmacokinetics of anthocyanins and their metabolites in humans201417132683282doi.org/10.1111/bph.12676.Search in Google Scholar
Ghareaghajlou N, Hallaj-Nezhadi S, Ghasempour Z. Red cabbage anthocyanins: Stability, extraction, biological activities and applications in food systems. Food Chem. 2021;365:130482. doi.org/10.1016/j.foodchem.2021.130482.GhareaghajlouNHallaj-NezhadiSGhasempourZRed cabbage anthocyanins: Stability, extraction, biological activities and applications in food systems2021365130482doi.org/10.1016/j.foodchem.2021.130482.Search in Google Scholar
Golovach NG, Cheshchevik VT, Lapshina EA, Ilyich TV, Zavodnik IB. Calcium-induced mitochondrial permeability transitions: Parameters of Ca2+ ion interactions with mitochondria and effects of oxidative agents. J Membr Biol. 2017;250:225–236. doi.org/10.1007/s00232-017-9953-2.GolovachNGCheshchevikVTLapshinaEAIlyichTVZavodnikIBCalcium-induced mitochondrial permeability transitions: Parameters of Ca2+ ion interactions with mitochondria and effects of oxidative agents2017250225236doi.org/10.1007/s00232-017-9953-2.Search in Google Scholar
Hao L, Sun Q, Zhong W, Zhang W, Sun X, Zhou Z. Mitochondria-targeted ubiquinone (MitoQ) enhances acetaldehyde clearance by reversing alcohol-induced posttranslational modification of aldehyde dehydrogenase 2: A molecular mechanism of protection against alcoholic liver disease. Redox Biol. 2018;14:626–636. doi.org/10.1016/j.redox.2017.11.005.HaoLSunQZhongWZhangWSunXZhouZMitochondria-targeted ubiquinone (MitoQ) enhances acetaldehyde clearance by reversing alcohol-induced posttranslational modification of aldehyde dehydrogenase 2: A molecular mechanism of protection against alcoholic liver disease201814626636doi.org/10.1016/j.redox.2017.11.005.Search in Google Scholar
Hassimoto NMA, Genovese MI, Laiolo FM. Antioxidant activity of dietary fruits, vegetables, and commercial frozen fruit pulps. J Agric Food Chem. 2005;53:2928–2935. doi.org/10.1021/jf047894h.HassimotoNMAGenoveseMILaioloFMAntioxidant activity of dietary fruits, vegetables, and commercial frozen fruit pulps20055329282935doi.org/10.1021/jf047894h.Search in Google Scholar
Hoek JB, Pastorino JG. Cellular signaling mechanisms in alcohol-induced liver damage. Semin Liver Dis. 2004;24:257–272. doi.org/10.1055/s-2004-832939.HoekJBPastorinoJGCellular signaling mechanisms in alcohol-induced liver damage200424257272doi.org/10.1055/s-2004-832939.Search in Google Scholar
Hou Z, Qin P, Ren G. Effect of anthocyanin-rich extract from black rice (Oryza sativa L. japonica) on chronically alcohol-induced liver damage in rats. J Agric Food Chem. 2010;58:3191–3196. https://doi.org/10.1021/jf904407x.HouZQinPRenGEffect of anthocyanin-rich extract from black rice (Oryza sativa L. japonica) on chronically alcohol-induced liver damage in rats20105831913196https://doi.org/10.1021/jf904407x.Search in Google Scholar
Johnson D, Lardy HA. Isolation of liver or kidney mitochondria. Meth Enzymol. 1967;10:94–101.JohnsonDLardyHAIsolation of liver or kidney mitochondria19671094101Search in Google Scholar
Khoo HE, Azlan A, Tang ST, Lim SM. Anthocyanidins and anthocyanins: Colored pigments as food, pharmaceutical ingredients, and the potential health benefits. Food Nutr Res. 2017;61:1361779. doi.org/10.1080/16546628.2017.1361779.KhooHEAzlanATangSTLimSMAnthocyanidins and anthocyanins: Colored pigments as food, pharmaceutical ingredients, and the potential health benefits2017611361779doi.org/10.1080/16546628.2017.1361779.Search in Google Scholar
Lapshina EA, Zamaraeva M, Cheshchevik VT, et al. Cranberry flavonoids prevent toxic rat liver mitochondrial damage in vivo and scavenge free radicals in vitro. Cell Biochem Funct. 2015;33:202–210. doi.org/10.1002/cbf.3104.LapshinaEAZamaraevaMCheshchevikVTCranberry flavonoids prevent toxic rat liver mitochondrial damage in vivo and scavenge free radicals in vitro201533202210doi.org/10.1002/cbf.3104.Search in Google Scholar
Lieber CS, DeCarli LM. Liquid diet technique of ethanol administration: 1989 update. Alcohol Alcohol. 1989;24:197–211.LieberCSDeCarliLMLiquid diet technique of ethanol administration: 1989 update198924197211Search in Google Scholar
Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951;193:265–275. doi.org/10.1016/S0021-9258(19)52451-6LowryOHRosebroughNJFarrALRandallRJProtein measurement with the Folin phenol reagent1951193265275doi.org/10.1016/S0021-9258(19)52451-6Search in Google Scholar
Lukivskaya OY, Naruta E, Sadovnichy V, Kirko S, Buko VU. Reversal of experimental ethanol-induced liver steatosis by borage oil. Phytother Res. 2012;26:1626–1631. doi.org/10.1002/ptr.4621.LukivskayaOYNarutaESadovnichyVKirkoSBukoVUReversal of experimental ethanol-induced liver steatosis by borage oil20122616261631doi.org/10.1002/ptr.4621.Search in Google Scholar
Mantena SK, King AL, Andringa KK, Eccleston HB, Bailey SM. Mitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases. Free Radic Biol Med. 2008;44:1259–1272. doi.org/10.1016/j.freeradbiomed.2007.12.029.MantenaSKKingALAndringaKKEcclestonHBBaileySMMitochondrial dysfunction and oxidative stress in the pathogenesis of alcohol- and obesity-induced fatty liver diseases20084412591272doi.org/10.1016/j.freeradbiomed.2007.12.029.Search in Google Scholar
Mathews S, Xu M, Wang H, Bertola A, Gao B. Animals models of gastrointestinal and liver diseases. Animal models of alcohol-induced liver disease: Pathophysiology, translational relevance, and challenges. Am J Physiol Gastrointest Liver Physiol. 2014;306:G819–G823. doi.org/10.1152/ajpgi.00041.2014.MathewsSXuMWangHBertolaAGaoBAnimals models of gastrointestinal and liver diseases. Animal models of alcohol-induced liver disease: Pathophysiology, translational relevance, and challenges2014306G819G823doi.org/10.1152/ajpgi.00041.2014.Search in Google Scholar
McDougall GJ, Fyffe S, Dobson P, Stewart D. Anthocyanins from red cabbage—Stability to simulated gastrointestinal digestion. Phytochemistry. 2007;68:1285–1294. doi.org/10.1016/j.phytochem.2007.02.004.McDougallGJFyffeSDobsonPStewartDAnthocyanins from red cabbage—Stability to simulated gastrointestinal digestion20076812851294doi.org/10.1016/j.phytochem.2007.02.004.Search in Google Scholar
Moore AL, Bonner WD. Measurements of membrane potentials in plant mitochondria with the safranine method. Plant Physiol. 1982;70:1271–1276. doi.org/10.1104/pp.70.5.1271.MooreALBonnerWDMeasurements of membrane potentials in plant mitochondria with the safranine method19827012711276doi.org/10.1104/pp.70.5.1271.Search in Google Scholar
Ni M-M, Xu T, Wang, Y-R, et al. Inhibition of IRF3 expression reduces TGF-β1-induced proliferation of hepatic stellate cells. J Physiol Biochem. 2016;72:9–23. doi.org/10.1007/s13105-015-0452-6.NiM-MXuTWangY-RInhibition of IRF3 expression reduces TGF-β1-induced proliferation of hepatic stellate cells201672923doi.org/10.1007/s13105-015-0452-6.Search in Google Scholar
Pan JH, Lim Y, Kim JH, et al. Root bark of Ulmus davidiana var. japonica restrains acute alcohol-induced hepatic steatosis onset in mice by inhibiting ROS accumulation. PLoS One. 2017;12:e0188381. doi.rg/10.1371/journal.pone.0188381.PanJHLimYKimJHRoot bark of Ulmus davidiana var. japonica restrains acute alcohol-induced hepatic steatosis onset in mice by inhibiting ROS accumulation201712e0188381doi.rg/10.1371/journal.pone.0188381.Search in Google Scholar
Pastorino JG, Hoek JB. Ethanol potentiates tumor necrosis factor-alpha cytotoxicity in hepatoma cells and primary rat hepatocytes by promoting induction of the mitochondrial permeability transition. Hepatol. 2000;31:1141–1152. doi.org/10.1053/he.2000.7013.PastorinoJGHoekJBEthanol potentiates tumor necrosis factor-alpha cytotoxicity in hepatoma cells and primary rat hepatocytes by promoting induction of the mitochondrial permeability transition20003111411152doi.org/10.1053/he.2000.7013.Search in Google Scholar
Rizzuto R, Stefani DD, Raffaello A, Mammucari C. Mitochondria as sensors and regulators of calcium signalling. Nat Rev Mol Cell Biol. 2012;13:566–578. doi.org/10.1038/nrm3412.RizzutoRStefaniDDRaffaelloAMammucariCMitochondria as sensors and regulators of calcium signalling201213566578doi.org/10.1038/nrm3412.Search in Google Scholar
Sozio M, Crabb DW. Alcohol and lipid metabolism. Am J Physiol Endocrinol Metab. 2008;295:E10–E16. doi.org/10.1152/ajpendo.00011.2008.SozioMCrabbDWAlcohol and lipid metabolism2008295E10E16doi.org/10.1152/ajpendo.00011.2008.Search in Google Scholar
Tang CC, Lin WL, Lee YJ, Tang YC, Wang CJ. Polyphenol-rich extract of Nelumbo nucifera leaves inhibits alcohol-induced steatohepatitis via reducing hepatic lipid accumulation and anti-inflammation in C57BL/6J mice. Food Funct. 2014;5:678–687. doi.org/10.1039/c3fo60478k.TangCCLinWLLeeYJTangYCWangCJPolyphenol-rich extract of Nelumbo nucifera leaves inhibits alcohol-induced steatohepatitis via reducing hepatic lipid accumulation and anti-inflammation in C57BL/6J mice20145678687doi.org/10.1039/c3fo60478k.Search in Google Scholar
Teschke R. Alcoholic liver disease: Alcohol metabolism, cascade of molecular mechanisms, cellular targets, and clinical aspects. Biomedicines. 2018;6:106. doi.org/10.3390/biomedicines6040106.TeschkeRAlcoholic liver disease: Alcohol metabolism, cascade of molecular mechanisms, cellular targets, and clinical aspects20186106doi.org/10.3390/biomedicines6040106.Search in Google Scholar
Tong T, Niu YH, Yue Y, Wu S-C, Ding H. Beneficial effects of anthocyanins from red cabbage (Brassica oleracea L. var. capitata L.) administration to prevent irinotecan-induced mucositis. J Funct Foods. 2017;32:9–17. doi.org/10.1016/j.jff.2017.01.051.TongTNiuYHYueYWuS-CDingHBeneficial effects of anthocyanins from red cabbage (Brassica oleracea L. var. capitata L.) administration to prevent irinotecan-induced mucositis201732917doi.org/10.1016/j.jff.2017.01.051.Search in Google Scholar
Xiao T, Luo Z, Guo Z, et al. Multiple roles of black raspberry anthocyanins protecting against alcoholic liver Disease. Molecules. 2021;26:2313. doi.org/10.3390/molecules26082313.XiaoTLuoZGuoZMultiple roles of black raspberry anthocyanins protecting against alcoholic liver Disease2021262313doi.org/10.3390/molecules26082313.Search in Google Scholar
Xu J, Cai Y, Wang H, et al. Fat-specific protein 27/CIDEC promotes development of alcoholic steatohepatitis in mice and humans. Gastroenterol. 2015;149:1030–1041. doi.org/10.1053/j.gastro.2015.06.009.XuJCaiYWangHFat-specific protein 27/CIDEC promotes development of alcoholic steatohepatitis in mice and humans201514910301041doi.org/10.1053/j.gastro.2015.06.009.Search in Google Scholar
Zavodnik IB, Buko V, Lukivskaya O, et al. Cranberry (Vaccinium macrocarpon) peel polyphenol-rich extract attenuates rat liver mitochondria impairments in alcoholic steatohepatitis in vivo and after oxidative treatment in vitro. J Funct Foods. 2019;57:83–94. doi.org/10.1016/j.jff.2019.04.001.ZavodnikIBBukoVLukivskayaOCranberry (Vaccinium macrocarpon) peel polyphenol-rich extract attenuates rat liver mitochondria impairments in alcoholic steatohepatitis in vivo and after oxidative treatment in vitro2019578394doi.org/10.1016/j.jff.2019.04.001.Search in Google Scholar
Zuo A, Wang S, Liu L, Yao Y, Guo J. Understanding the effect of anthocyanin extracted from Lonicera caerulea L. on alcoholic hepatosteatosis. Biomed Pharmacother. 2019;117:109087. doi.org/10.1016/j.biopha.2019.109087.ZuoAWangSLiuLYaoYGuoJUnderstanding the effect of anthocyanin extracted from Lonicera caerulea L. on alcoholic hepatosteatosis2019117109087doi.org/10.1016/j.biopha.2019.109087.Search in Google Scholar