<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Canine babesiosis is a tick-borne disease caused by protozoal haemoparasites of different <italic>Babesia</italic> species. Babesiosis is one of the most important globally extended and quickly spreading tick-borne infections of dogs. This comprehensive review gives an in-depth overview of <italic>Babesia</italic> species currently identified in dogs together with relevant vector tick species and their geographical distribution, life cycle and transmission of parasite. The main mechanisms in the pathogenesis of babesiosis are described and elucidated by recent literature overview. As <italic>Babesia</italic> infection causes a disease with very variable clinical manifestations, special attention is given to clinical signs, laboratory features and clinicopathological findings. The diagnosis of canine babesiosis by microscopy, serological and molecular methods is reviewed, together with recent advances in mass spectrometry based assays. Accurate detection and species recognition are important for the selection of the appropriate therapy, monitoring and prediction of the outcome of the disease. Finally, guidelines for the treatment and prevention of canine babesiosis are given.</p></abstract>

Canine babesiosis is a tick-borne disease caused by protozoal haemoparasites of different Babesia species. Babesiosis is one of the most important globally extended and quickly spreading tick-borne infections of dogs. This comprehensive review gives an in-depth overview of Babesia species currently identified in dogs together with relevant vector tick species and their geographical distribution, life cycle and transmission of parasite. The main mechanisms in the pathogenesis of babesiosis are described and elucidated by recent literature overview. As Babesia infection causes a disease with very variable clinical manifestations, special attention is given to clinical signs, laboratory features and clinicopathological findings. The diagnosis of canine babesiosis by microscopy, serological and molecular methods is reviewed, together with recent advances in mass spectrometry based assays. Accurate detection and species recognition are important for the selection of the appropriate therapy, monitoring and prediction of the outcome of the disease. Finally, guidelines for the treatment and prevention of canine babesiosis are given.

Canine Babesiosis: Where Do We Stand?

Clinic for Internal Diseases, Faculty of Veterinary Medicine

VetMedZg, Clinic for Internal Diseases, Faculty of Veterinary Medicine

Department of Chemistry and Biochemistry, Faculty of Veterinary Medicine

Acta Veterinaria

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Canine Babesiosis: Where Do We Stand?"}

Canine babesiosis is a tick-borne disease caused by protozoal haemoparasites of different Babesia species. Babesiosis is one of the most important globally...

Canine Babesiosis: Where Do We Stand?

Online veröffentlicht: 04. Juli 2018

Seitenbereich: 127 - 160

Eingereicht: 08. Mai 2018

Akzeptiert: 29. Mai 2018

DOI: https://doi.org/10.2478/acve-2018-0011

Schlüsselwörter
babesiosis, dog, pathogenesis, tick-borne disease

© 2018 Bilić Petra et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Canine Babesiosis: Where Do We Stand?

Online veröffentlicht: 04. Juli 2018

Seitenbereich: 127 - 160

Eingereicht: 08. Mai 2018

Akzeptiert: 29. Mai 2018

DOI: https://doi.org/10.2478/acve-2018-0011

Schlüsselwörterbabesiosis, dog, pathogenesis, tick-borne disease

© 2018 Bilić Petra et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Schlüsselwörter
babesiosis, dog, pathogenesis, tick-borne disease