Organotin (IV) based Rabeprazole and Pregabalin Complexes Formation and Biocidal Investigation

New organotin (IV) complexes with NaL¹ (sodium salt of 2-[[4-(3-methoxy-propoxy) 3-methylpyridin-2-yl]methylsulfinyl]benzimidazol-1-ide) and NaL² (sodium salt of 3- aminomethyl-5-methylhexanoic acid) were synthesized by the reaction of diorganotin (IV) and triorganotin (IV) salt (Bu₃SnCl, Ph₃SnCl, Bu₂SnCl₂, Me₂SnCl₂) using the solvent (dry toluene) by constant stirring and refluxing. All the organotin (IV) complexes were characterized by different diagnostic techniques such as FT-IR (Infra-red) and UV-visible spectroscopy. The results exhibited that ligand NaL¹ (sodium salt) is attached to tin metal by a nitrogen atom of benzimidazole ring and the oxygen atom of the sulfonyl group. While ligand NaL² (sodium salt) coordinate with tin(IV) moiety through oxygen atom of the carboxylate group. The newly synthesized complexes 1 & 2 of ligand NaL¹ (sodium salt) showed trigonal bipyramidal geometry while complexes 3 & 4 octahedral geometry around tin(IV) centre. The organotin(IV) complexes 5-7 of ligand NaL² (sodium salt) have the tetrahedral geometry around tin(IV) centre. The synthesized complexes (1-7) were tested for antifungal and antibacterial microbial activities. All the complexes showed significant antibacterial and anti-fungal activities against tested bacterial and fungal strains.