This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Greenberg MI, Waksman J, Curtis J. Silicosis: a review. Dis Mon 2007; 53 (8): 394-416.GreenbergMIWaksmanJCurtisJSilicosis: a reviewDis Mon200753839441610.1016/j.disamonth.2007.09.02017976433Search in Google Scholar
Hamilton RF Jr, Thakur SA, Holian A. Silica binding and toxicity in alveolar macrophages. Free Radic Biol Med 2008; 44 (7): 1246-58.HamiltonRFJrThakurSAHolianASilica binding and toxicity in alveolar macrophagesFree Radic Biol Med200844712465810.1016/j.freeradbiomed.2007.12.027268095518226603Search in Google Scholar
Harijith A, Ebenezer DL, Natarajan V. Reactive oxygen species at the crossroads of inflammasome and inflammation. Front Physiol 2014; 5: 352.HarijithAEbenezerDLNatarajanVReactive oxygen species at the crossroads of inflammasome and inflammationFront Physiol2014535210.3389/fphys.2014.00352417932325324778Search in Google Scholar
Pollard KM. Silica, Silicosis, and Autoimmunity. Front Immunol 2016; 7: 97.PollardKMSilica, Silicosis, and AutoimmunityFront Immunol201679710.3389/fimmu.2016.00097478655127014276Search in Google Scholar
Sayan M, Mossman BT. The NLRP3 inflammasome in pathogenic particle and fibre-associated lung inflammation and diseases. Part Fibre Toxicol 2016; 13 (1): 51.SayanMMossmanBTThe NLRP3 inflammasome in pathogenic particle and fibre-associated lung inflammation and diseasesPart Fibre Toxicol20161315110.1186/s12989-016-0162-4502901827650313Search in Google Scholar
Barnes H, Goh NSL, Leong TL, Hoy R. Silica associated lung disease: An old world exposure in modern industries. Respirology 2019; 24 (12): 1165-75.BarnesHGohNSLLeongTLHoyRSilica associated lung disease: An old world exposure in modern industriesRespirology2019241211657510.1111/resp.1369531517432Search in Google Scholar
Adamcakova J, Mokra D. New Insights into Pathomechanisms and Treatment Possibilities for Lung Silicosis. Int J Mol Sci 2021; 22 (8): 4162.AdamcakovaJMokraDNew Insights into Pathomechanisms and Treatment Possibilities for Lung SilicosisInt J Mol Sci2021228416210.3390/ijms22084162807289633920534Search in Google Scholar
Adamcakova J, Mokra D. Herbal compounds in the treatment of pulmonary silicosis. Physiol Res 2021; 70 (S3): S275-87.AdamcakovaJMokraDHerbal compounds in the treatment of pulmonary silicosisPhysiol Res202170S3S2758710.33549/physiolres.934817888439335099247Search in Google Scholar
Gharaee-Kermani M, Ullenbruch M, Phan SH. Animal models of pulmonary fibrosis. Methods Mol Med 2005; 117: 251-9.Gharaee-KermaniMUllenbruchMPhanSHAnimal models of pulmonary fibrosisMethods Mol Med2005117251910.1385/1-59259-940-0:25116118457Search in Google Scholar
Lakatos HF, Burgess HA, Thatcher TH, Redonnet MR, Hernady E, Williams JP, Sime PJ. Oropharyngeal aspiration of a silica suspension produces a superior model of silicosis in the mouse when compared to intratracheal instillation. Exp Lung Res 2006; 32 (5): 181-99.LakatosHFBurgessHAThatcherTHRedonnetMRHernadyEWilliamsJPSimePJOropharyngeal aspiration of a silica suspension produces a superior model of silicosis in the mouse when compared to intratracheal instillationExp Lung Res20063251819910.1080/0190214060081746516908446Search in Google Scholar
Zhang H, Yin G, Jiang H, Zhang C. High-dose N-acetylcysteine decreases silica-induced lung fibrosis in the rat. J Int Med Res 2013; 41 (4): 1179-86.ZhangHYinGJiangHZhangCHigh-dose N-acetylcysteine decreases silica-induced lung fibrosis in the ratJ Int Med Res201341411798610.1177/030006051348850323771710Search in Google Scholar
Luo C, Ji X, Fan J, Hou Z, Wang T, Wu B, Ni C. Annexin A5 promotes macrophage activation and contributes to pulmonary fibrosis induced by silica particles. Toxicol Ind Health 2016; 32 (9): 1628-38.LuoCJiXFanJHouZWangTWuBNiCAnnexin A5 promotes macrophage activation and contributes to pulmonary fibrosis induced by silica particlesToxicol Ind Health201632916283810.1177/074823371557274425757482Search in Google Scholar
Porter DW, Ye J, Ma J, Barger M, Robinson VA, Ramsey D, McLaurin J, Khan A, Landsittel D, Teass A, Castranova V. Time course of pulmonary response of rats to inhalation of crystalline silica: NF-kappa B activation, inflammation, cytokine production, and damage. Inhal Toxicol 2002; 14 (4): 349-67.PorterDWYeJMaJBargerMRobinsonVARamseyDMcLaurinJKhanALandsittelDTeassACastranovaVTime course of pulmonary response of rats to inhalation of crystalline silica: NF-kappa B activation, inflammation, cytokine production, and damageInhal Toxicol20021443496710.1080/0895837025287099812028809Search in Google Scholar
Øvrevik J, Refsnes M, Låg M, Holme JA, Schwarze PE. Activation of Proinflammatory Responses in Cells of the Airway Mucosa by Particulate Matter: Oxidant- and Non-Oxidant-Mediated Triggering Mechanisms. Biomolecules 2015; 5 (3): 1399-440.ØvrevikJRefsnesMLågMHolmeJASchwarzePEActivation of Proinflammatory Responses in Cells of the Airway Mucosa by Particulate Matter: Oxidant- and Non-Oxidant-Mediated Triggering MechanismsBiomolecules201553139944010.3390/biom5031399459875726147224Search in Google Scholar
Bowden DH, Hedgecock C, Adamson IY. Silica-induced pulmonary fibrosis involves the reaction of particles with interstitial rather than alveolar macrophages. J Pathol 1989; 158 (1): 73-80.BowdenDHHedgecockCAdamsonIYSilica-induced pulmonary fibrosis involves the reaction of particles with interstitial rather than alveolar macrophagesJ Pathol19891581738010.1002/path.17115801142547046Search in Google Scholar
Peeters PM, Eurlings IM, Perkins TN, Wouters EF, Schins RP, Borm PJ, Drommer W, Reynaert NL, Albrecht C. Silica-induced NLRP3 inflammasome activation in vitro and in rat lungs. Part Fibre Toxicol 2014; 11: 58.PeetersPMEurlingsIMPerkinsTNWoutersEFSchinsRPBormPJDrommerWReynaertNLAlbrechtCSilica-induced NLRP3 inflammasome activation in vitro and in rat lungsPart Fibre Toxicol2014115810.1186/s12989-014-0058-0424327825406505Search in Google Scholar
Abdelaziz RR, Elkashef WF, Said E. Tadalafil reduces airway hyperactivity and protects against lung and respiratory airways dysfunction in a rat model of silicosis. Int Immunopharmacol 2016; 40: 530-41.AbdelazizRRElkashefWFSaidETadalafil reduces airway hyperactivity and protects against lung and respiratory airways dysfunction in a rat model of silicosisInt Immunopharmacol2016405304110.1016/j.intimp.2016.10.00727769022Search in Google Scholar
El-Kashef DH. Nicorandil ameliorates pulmonary inflammation and fibrosis in a rat model of silicosis. Int Immunopharmacol 2018; 64: 289-97.El-KashefDH.Nicorandil ameliorates pulmonary inflammation and fibrosis in a rat model of silicosisInt Immunopharmacol2018642899710.1016/j.intimp.2018.09.01730223191Search in Google Scholar
Rabolli V, Lo Re S, Uwambayinema F, Yakoub Y, Lison D, Huaux F. Lung fibrosis induced by crystalline silica particles is uncoupled from lung inflammation in NMRI mice. Toxicol Lett 2011; 203 (2): 127-34.RabolliVLoRe SUwambayinemaFYakoubYLisonDHuauxFLung fibrosis induced by crystalline silica particles is uncoupled from lung inflammation in NMRI miceToxicol Lett201120321273410.1016/j.toxlet.2011.03.00921414392Search in Google Scholar
Luo C, Ji X, Fan J, Hou Z, Wang T, Wu B, Ni C. Annexin A5 promotes macrophage activation and contributes to pulmonary fibrosis induced by silica particles. Toxicol Ind Health 2016; 32 (9): 1628-1638.LuoCJiXFanJHouZWangTWuBNiCAnnexin A5 promotes macrophage activation and contributes to pulmonary fibrosis induced by silica particlesToxicol Ind Health20163291628163810.1177/074823371557274425757482Search in Google Scholar
Arras M, Huaux F, Vink A, Delos M, Coutelier JP, Many MC, Barbarin V, Renauld JC, Lison D. Interleukin-9 reduces lung fibrosis and type 2 immune polarization induced by silica particles in a murine model. Am J Respir Cell Mol Biol 2001; 24 (4): 368-375.ArrasMHuauxFVinkADelosMCoutelierJPManyMCBarbarinVRenauldJCLisonDInterleukin-9 reduces lung fibrosis and type 2 immune polarization induced by silica particles in a murine modelAm J Respir Cell Mol Biol200124436837510.1165/ajrcmb.24.4.424911306428Search in Google Scholar
Zhu Z, Yang G, Wang Y, Yang J, Gao A, Niu P, Tian L. Suppression of thioredoxin system contributes to silica-induced oxidative stress and pulmonary fibrogenesis in rats. Toxicol Lett 2013; 222 (3): 289-294.ZhuZYangGWangYYangJGaoANiuPTianLSuppression of thioredoxin system contributes to silica-induced oxidative stress and pulmonary fibrogenesis in ratsToxicol Lett2013222328929410.1016/j.toxlet.2013.08.00423973437Search in Google Scholar
Czock D, Keller F, Rasche FM, Häussler U. Pharmacokinetics and pharmacodynamics of systemically administered glucocorticoids. Clin Pharmacokinet 2005; 44 (1): 61-98.CzockDKellerFRascheFMHäusslerUPharmacokinetics and pharmacodynamics of systemically administered glucocorticoidsClin Pharmacokinet2005441619810.2165/00003088-200544010-0000315634032Search in Google Scholar
Stahn C, Buttgereit F. Genomic and nongenomic effects of glucocorticoids. Nat Clin Pract Rheumatol 2008; 4 (10): 525-33.StahnCButtgereitFGenomic and nongenomic effects of glucocorticoidsNat Clin Pract Rheumatol20084105253310.1038/ncprheum089818762788Search in Google Scholar
Song CZ, Tian X, Gelehrter TD. Glucocorticoid receptor inhibits transforming growth factor-beta signaling by directly targeting the transcriptional activation function of Smad3. Proc Natl Acad Sci U S A 1999; 96 (21): 11776-81.SongCZTianXGelehrterTDGlucocorticoid receptor inhibits transforming growth factor-beta signaling by directly targeting the transcriptional activation function of Smad3Proc Natl Acad Sci U S A19999621117768110.1073/pnas.96.21.117761836210518526Search in Google Scholar
Rhen T, Cidlowski JA. Antiinflammatory action of glucocorticoids--new mechanisms for old drugs. N Engl J Med 2005; 353 (16): 1711-23.RhenTCidlowskiJAAntiinflammatory action of glucocorticoids--new mechanisms for old drugsN Engl J Med20053531617112310.1056/NEJMra05054116236742Search in Google Scholar
Rogatsky I, Ivashkiv LB. Glucocorticoid modulation of cytokine signaling. Tissue Antigens 2006; 68 (1): 1-12.RogatskyIIvashkivLBGlucocorticoid modulation of cytokine signalingTissue Antigens200668111210.1111/j.1399-0039.2006.00599.x16774534Search in Google Scholar
Mokra D, Mikolka P, Kosutova P, Mokry J. Corticosteroids in Acute Lung Injury: The Dilemma Continues. Int J Mol Sci 2019; 20 (19): 4765.MokraDMikolkaPKosutovaPMokryJCorticosteroids in Acute Lung Injury: The Dilemma ContinuesInt J Mol Sci20192019476510.3390/ijms20194765680169431557974Search in Google Scholar
Trentin PG, Ferreira TP, Arantes AC, Ciambarella BT, Cordeiro RS, Flower RJ, Perretti M, Martins MA, Silva PM. Annexin A1 mimetic peptide controls the inflammatory and fibrotic effects of silica particles in mice. Br J Pharmacol 2015; 172 (12): 3058-71.TrentinPGFerreiraTPArantesACCiambarellaBTCordeiroRSFlowerRJPerrettiMMartinsMASilvaPMAnnexin A1 mimetic peptide controls the inflammatory and fibrotic effects of silica particles in miceBr J Pharmacol20151721230587110.1111/bph.13109445902325659822Search in Google Scholar
Dik WA, McAnulty RJ, Versnel MA, Naber BA, Zimmermann LJ, Laurent GJ, Mutsaers SE. Short course dexamethasone treatment following injury inhibits bleomycin induced fibrosis in rats. Thorax 2003; 58 (9): 765-71.DikWAMcAnultyRJVersnelMANaberBAZimmermannLJLaurentGJMutsaersSEShort course dexamethasone treatment following injury inhibits bleomycin induced fibrosis in ratsThorax20035897657110.1136/thorax.58.9.765174681212947134Search in Google Scholar
Barbarin V, Nihoul A, Misson P, Arras M, Delos M, Leclercq I, Lison D, Huaux F. The role of proand anti-inflammatory responses in silica-induced lung fibrosis. Respir Res 2005; 6 (1): 112.BarbarinVNihoulAMissonPArrasMDelosMLeclercqILisonDHuauxFThe role of proand anti-inflammatory responses in silica-induced lung fibrosisRespir Res20056111210.1186/1465-9921-6-112127434616212659Search in Google Scholar
Van Dyke K, Antonini JM, Wu L, Ye Z, Reasor MJ. The inhibition of silica-induced lung inflammation by dexamethasone as measured by bronchoalveolar lavage fluid parameters and peroxynitrite-dependent chemiluminescence. Agents Actions 1994; 41 (1-2): 44-9.VanDyke KAntoniniJMWuLYeZReasorMJThe inhibition of silica-induced lung inflammation by dexamethasone as measured by bronchoalveolar lavage fluid parameters and peroxynitrite-dependent chemiluminescenceAgents Actions1994411-244910.1007/BF019863928079820Search in Google Scholar
Sacks M, Gordon J, Bylander J, Porter D, Shi XL, Castranova V, Kaczmarczyk W, Van Dyke K, Reasor MJ. Silica-induced pulmonary inflammation in rats: activation of NF-kappa B and its suppression by dexamethasone. Biochem Biophys Res Commun 1998; 253 (1): 181-4.SacksMGordonJBylanderJPorterDShiXLCastranovaVKaczmarczykWVanDyke KReasorMJSilica-induced pulmonary inflammation in rats: activation of NF-kappa B and its suppression by dexamethasoneBiochem Biophys Res Commun19982531181410.1006/bbrc.1998.97639875241Search in Google Scholar
Mokra D, Mokry J, Drgova A, Bulikova J, Petraskova M, Calkovska A. Single-dose versus two-dose dexamethasone effects on lung inflammation and airway reactivity in meconium-instilled rabbits. J Physiol Pharmacol 2007; 58 (Suppl 5): 379-87.MokraDMokryJDrgovaABulikovaJPetraskovaMCalkovskaASingle-dose versus two-dose dexamethasone effects on lung inflammation and airway reactivity in meconium-instilled rabbitsJ Physiol Pharmacol200758Suppl 537987Search in Google Scholar
Mikolka P, Kosutova P, Kolomaznik M, Topercerova J, Kopincova J, Calkovska A, Mokra D. Effect of different dosages of dexamethasone therapy on lung function and inflammation in an early phase of acute respiratory distress syndrome model. Physiol Res 2019; 68 (Suppl 3): S253-63.MikolkaPKosutovaPKolomaznikMTopercerovaJKopincovaJCalkovskaAMokraDEffect of different dosages of dexamethasone therapy on lung function and inflammation in an early phase of acute respiratory distress syndrome modelPhysiol Res201968Suppl 3S2536310.33549/physiolres.93436431928043Search in Google Scholar
Soukka H, Halkola L, Aho H, Rautanen M, Kero P, Kääpä P. Methylprednisolone attenuates the pulmonary hypertensive response in porcine meconium aspiration. Pediatr Res 1997; 42 (2): 145-50.SoukkaHHalkolaLAhoHRautanenMKeroPKääpäPMethylprednisolone attenuates the pulmonary hypertensive response in porcine meconium aspirationPediatr Res19974221455010.1203/00006450-199708000-000039262214Search in Google Scholar
Holopainen R, Laine J, Halkola L, Aho H, Kääpä P. Dexamethasone treatment attenuates pulmonary injury in piglet meconium aspiration. Pediatr Res 2001; 49 (2): 162-8.HolopainenRLaineJHalkolaLAhoHKääpäPDexamethasone treatment attenuates pulmonary injury in piglet meconium aspirationPediatr Res2001492162810.1203/00006450-200102000-0000611158508Search in Google Scholar
Dubois EF, Derks MG, Schweitzer DH, Zwinderman AH, Dekhuijzen PN, van Boxtel CJ. Pharmacokinetic/pharmacodynamic modelling of effects of dexamethasone and prednisolone in combination with endogenous cortisol on lymphocyte counts and systemic markers of bone turn over and inflammation in healthy and asthmatic men. Eur J Clin Pharmacol 2004; 60 (5): 315-28.DuboisEFDerksMGSchweitzerDHZwindermanAHDekhuijzenPNvanBoxtel CJPharmacokinetic/pharmacodynamic modelling of effects of dexamethasone and prednisolone in combination with endogenous cortisol on lymphocyte counts and systemic markers of bone turn over and inflammation in healthy and asthmatic menEur J Clin Pharmacol20046053152810.1007/s00228-004-0738-z15150679Search in Google Scholar
Vrlik M, Dzurilla M, Bucova M, Kantarova D, Buc M. Asthma bronchiale phenotypes and their treat ment − a current view. Acta Med Mart 2009, 9 (3): 3-11.VrlikMDzurillaMBucovaMKantarovaDBucMAsthma bronchiale phenotypes and their treat ment − a current viewActa Med Mart200993311Search in Google Scholar
Paľová R, Adamčáková J, Mokrá D, Mokrý J. Bronchial asthma: current trends in treatment. Acta Med Mart 2020; 20 (1): 9-17.PaľováRAdamčákováJMokráDMokrýJBronchial asthma: current trends in treatmentActa Med Mart202020191710.2478/acm-2020-0002Search in Google Scholar
Osinová D, Sadloňová J, Rozborilová E. Exacerbations of Chronic Obstructive Pulmonary Disease and Implementation of Guidelines Gold 2011 in Practice. Acta Med Mart 2015; 15 (2): 13-20.OsinováDSadloňováJRozborilováEExacerbations of Chronic Obstructive Pulmonary Disease and Implementation of Guidelines Gold 2011 in PracticeActa Med Mart2015152132010.1515/acm-2015-0007Search in Google Scholar
Abdel Kawy HS. Montelukast versus Dexamethasone Treatment in a Guinea Pig Model of Chronic Pulmonary Neutrophilic Inflammation. COPD 2016; 13 (4): 455-63.Abdel Kawy HSMontelukast versus Dexamethasone Treatment in a Guinea Pig Model of Chronic Pulmonary Neutrophilic InflammationCOPD20161344556310.3109/15412555.2015.104604126751767Search in Google Scholar
Rodrigues SO, Cunha CMCD, Soares GMV, Silva PL, Silva AR, Gonçalves-de-Albuquerque CF. Mechanisms, Pathophysiology and Currently Proposed Treatments of Chronic Obstructive Pulmonary Disease. Pharmaceuticals (Basel) 2021; 14 (10): 979.RodriguesSOCunhaCMCDSoaresGMVSilvaPLSilvaARGonçalves-de-AlbuquerqueCFMechanisms, Pathophysiology and Currently Proposed Treatments of Chronic Obstructive Pulmonary DiseasePharmaceuticals (Basel)2021141097910.3390/ph14100979853995034681202Search in Google Scholar
Wittermans E, van de Garde EM, Voorn GP, Aldenkamp AF, Janssen R, Grutters JC, Bos WJW; Santeon-CAP study group. Neutrophil count, lymphocyte count and neutrophil-to-lymphocyte ratio in relation to response to adjunctive dexamethasone treatment in community-acquired pneumonia. Eur J Intern Med 2022; 96: 102-8.WittermansEvande Garde EMVoornGPAldenkampAFJanssenRGruttersJCBosWJW; Santeon-CAP study groupNeutrophil count, lymphocyte count and neutrophil-to-lymphocyte ratio in relation to response to adjunctive dexamethasone treatment in community-acquired pneumoniaEur J Intern Med202296102810.1016/j.ejim.2021.10.03034782191Search in Google Scholar
Mokra D, Mokry J, Calkovska A. Anti-inflammatory drugs in the treatment of meconium aspiration syndrome. Acta Med Mart 2011, 11 (Suppl 1): 15-23.MokraDMokryJCalkovskaAAnti-inflammatory drugs in the treatment of meconium aspiration syndromeActa Med Mart201111Suppl 1152310.2478/v10201-011-0007-7Search in Google Scholar
Gharaee-Kermani M, Hatano K, Nozaki Y, Phan SH. Gender-based differences in bleomycin-induced pulmonary fibrosis. Am J Pathol 2005; 166 (6): 1593-606.Gharaee-KermaniMHatanoKNozakiYPhanSHGender-based differences in bleomycin-induced pulmonary fibrosisAm J Pathol20051666159360610.1016/S0002-9440(10)62470-4160242915920145Search in Google Scholar
Ray JL, Holian A. Sex differences in the inflammatory immune response to multi-walled carbon nanotubes and crystalline silica. Inhal Toxicol 2019; 31 (7): 285-97.RayJLHolianASex differences in the inflammatory immune response to multi-walled carbon nanotubes and crystalline silicaInhal Toxicol20193172859710.1080/08958378.2019.1669743681377531556754Search in Google Scholar
