<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec><h3>Background</h3>
<p>Eosinophilia is a common, hematologic abnormality detected in periodic health checkups with diverse etiologies. There are a few clinical practice guidelines for the management of eosinophilia.</p>
</sec>
<sec><h3>Objectives</h3>
<p>To determine the prevalence of eosinophilia among patients undergoing periodic health examinations, evaluate its management and outcomes, and identify its associated factors.</p>
</sec>
<sec><h3>Methods</h3>
<p>We conducted a retrospective study that included patients with eosinophilia diagnosed during the 2018 periodic health examinations at Songklanagarind Hospital.</p>
</sec>
<sec><h3>Results</h3>
<p>The prevalence rate of eosinophilia was 9.6% (988/10,299), and most patients (52.6%) were male with a median age of 53.0 (42.0–61.0) years. Only 174 patients (17.6%) were diagnosed and further examined to identify the cause of eosinophilia; including an examination of medical history (18.4%), physical examination (93.1%), laboratory analysis (9.2%), and consultation with internists (14.9%). Empirical anthelmintic therapy was administered in 130 patients (74.7%), and 49.2% achieved resolution. The possible causes of eosinophilia were identified in 20.7% (204/988), the most common cause being atopic disease (51.5%). Patients with moderate-to-severe eosinophilia were significantly more likely to be diagnosed, undergo further laboratory tests, and proceed with consultations with internists (adjusted OR [95% CI] = 3.52 [1.97–6.32], 17.13 [5.74–51.11], and 6.38 [1.95–20.93], respectively).</p>
</sec>
<sec><h3>Conclusions</h3>
<p>Eosinophilia is commonly identified in periodic health examinations, and most primary physicians lack knowledge regarding the diagnostic work-up required to determine the cause of eosinophilia. Empirical anthelmintic therapy showed satisfactory efficacy for the management of eosinophilia in areas where parasite infection is endemic.</p>
</sec>
</abstract>

Background
Eosinophilia is a common, hematologic abnormality detected in periodic health checkups with diverse etiologies. There are a few clinical practice guidelines for the management of eosinophilia.

Objectives
To determine the prevalence of eosinophilia among patients undergoing periodic health examinations, evaluate its management and outcomes, and identify its associated factors.

Methods
We conducted a retrospective study that included patients with eosinophilia diagnosed during the 2018 periodic health examinations at Songklanagarind Hospital.

Results
The prevalence rate of eosinophilia was 9.6% (988/10,299), and most patients (52.6%) were male with a median age of 53.0 (42.0–61.0) years. Only 174 patients (17.6%) were diagnosed and further examined to identify the cause of eosinophilia; including an examination of medical history (18.4%), physical examination (93.1%), laboratory analysis (9.2%), and consultation with internists (14.9%). Empirical anthelmintic therapy was administered in 130 patients (74.7%), and 49.2% achieved resolution. The possible causes of eosinophilia were identified in 20.7% (204/988), the most common cause being atopic disease (51.5%). Patients with moderate-to-severe eosinophilia were significantly more likely to be diagnosed, undergo further laboratory tests, and proceed with consultations with internists (adjusted OR [95% CI] = 3.52 [1.97–6.32], 17.13 [5.74–51.11], and 6.38 [1.95–20.93], respectively).

Conclusions
Eosinophilia is commonly identified in periodic health examinations, and most primary physicians lack knowledge regarding the diagnostic work-up required to determine the cause of eosinophilia. Empirical anthelmintic therapy showed satisfactory efficacy for the management of eosinophilia in areas where parasite infection is endemic.

Prevalence and management of eosinophilia based on periodic health examinations in primary care clinics

Division of Family and Preventive Medicine, Faculty of Medicine

Division of Internal Medicine, Faculty of Medicine

Asian Biomedicine

This work is licensed under the Creative Commons Attribution 4.0 International License.

Background
Eosinophilia is a common, hematologic abnormality detected in periodic health checkups with diverse etiologies. There are a few clinical practice...

Prevalence and management of eosinophilia based on periodic health examinations in primary care clinics

Article Category: Original article

Online veröffentlicht: 16. Juni 2023

Seitenbereich: 273 - 282

DOI: https://doi.org/10.2478/abm-2022-0030

Schlüsselwörter
anthelmintic, eosinophilia, prevalence, therapeutics, periodic health examinations

© 2022 Thareerat Ananchaisarp et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Prevalence and management of eosinophilia based on periodic health examinations in primary care clinics

Article Category: Original article

Online veröffentlicht: 16. Juni 2023

Seitenbereich: 273 - 282

DOI: https://doi.org/10.2478/abm-2022-0030

Schlüsselwörteranthelmintic, eosinophilia, prevalence, therapeutics, periodic health examinations

© 2022 Thareerat Ananchaisarp et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Schlüsselwörter
anthelmintic, eosinophilia, prevalence, therapeutics, periodic health examinations