Severe intravascular hemolysis due to autoantibodies stimulated by blood transfusion
, , , , und
10. Nov. 2020
Über diesen Artikel
Online veröffentlicht: 10. Nov. 2020
Seitenbereich: 80 - 83
DOI: https://doi.org/10.21307/immunohematology-2019-751
Schlüsselwörter
© 1996 D. Chan et al., published by Sciendo
Autoantibodies may cause severe hemolytic anemia, but only rarely are they the cause of a hemolytic transfusion reaction due to the destruction of transfused allogeneic blood. In two patients, autoantibody was detected shortly after blood transfusion. The first case was a D-negative patient who produced an autoanti-Ce and subsequently developed hemoglobinuria and hyperbilirubinemia. The second case was a patient who developed an autoanti-Wrb that caused severe hemolysis that resulted in death.