From kill to overkill: 100 years of (perhaps too much) progress

1Landsteiner, K. Zur Kenntnis der antifermentativen, lytischen und agglutinierenden Wirkungen des Blutserums und der Lymphe. Zbl fur Bakt, Parasit und Infekt 1900;27:357–62. (This paper was the first to mention discovery of the ABO groups. However, relatively brief details are given. A more complete account, including mention of the probable importance of the findings in transfusion therapy, appeared one year later in: Landsteiner K. Über Agglutinat- ionserscheinungen normalen menschl ichen Blutes. Wien klin Wschr 1901;14:1132–4. An English translation of the 1901 paper, by Professor A.L. Kappus, was published in Transfusion 1961; 1:5–8).Search in Google Scholar

2Walton HH. Remarks, statistical and general on transfusion of blood. The Medical Times 1849;114–7.Search in Google Scholar

3Ottenberg R. Transfusion and arterial anastomosis. Some experiments in arterial anastomosis and a study of transfusion with presentation of two clinical cases. Ann Surg 1908;47:486–505.10.1097/00000658-190804000-00002Search in Google Scholar

4Ottenberg R. Studies on isoagglutination. I. Transfusion and the question of intravascular agglutination. J Exp Med 1911;13:425–38.10.1084/jem.13.4.425Search in Google Scholar

5Ottenberg R, Kaliski DJ. Accidents in transfusion. Their prevention by preliminary blood examination: based on experience of one hundred and twentyeight transfusions. J Am Med Assoc 1913; 61: 2138–40.10.1001/jama.1913.04350250024007Search in Google Scholar

6Ottenberg R, Thalheimer W. Studies in experimental transfusion. J Med Res 1913;33:213–29.Search in Google Scholar

7Weil R. Sodium citrate in the transfusion of blood. J Am Med Assoc 1915;64:425–6.Search in Google Scholar

8Unger LJ. Precautions necessary in the selection of a donor for blood transfusion. J Am Med Assoc 1921;76:9–11.10.1001/jama.1921.02630010013003Search in Google Scholar

9Ottenberg R. Reminiscences of the history of blood transfusion. J Mt Sinai Hosp 1937;4:264–71.Search in Google Scholar

10Cameron JW, Diamond LK. Chemical, clinical and immunological studies on the products of human plasma fractionation. XXIX. Serum albumin as a diluent for Rh typing reagents. J Clin Invest 1945; 24:793–801.10.1172/JCI101665Search in Google Scholar

11Diamond LK, Denton RL. Rh agglutination in various media with particular reference to the value of albu- min. J Lab Clin Med 1945;30:821–30.Search in Google Scholar

12Diamond LK, Abelson NM. The demonstration of anti- Rh agglutinins, an accurate and rapid slide test. J Lab Clin Med 1945;30:204–12.Search in Google Scholar

13Diamond LK, Abelson NM. The detection of Rh sen- sitization:evaluations of tests for Rh antibodies. J Lab Clin Med 1945;30:668–74.Search in Google Scholar

14Coombs RRA, Mourant AE, Race RR. A new test for the detection of weak and “incomplete” Rh agglutinins. Br J Exp Pathol 1945;26:255–66.10.1007/978-94-011-6138-1_10Search in Google Scholar

15Moreschi C. Neue Ta tsachen über die Blutkörperchen Agglutination. Zbl Bakt 1908; 46:49–51.Search in Google Scholar

16Coombs RRA, Mourant AE, Race RR. In vivo isosensitization of red cells in babies with haemolytic disease. Lancet 1946;i:264–6.10.1016/S0140-6736(46)91925-3Search in Google Scholar

17Pickles MM. Effects of cholera filtrate on red cells as demonstrated by incomplete Rh antibodies. Nature 1946;158:880.10.1038/158880a020279056Search in Google Scholar

18Morton JA, Pickles MM. Use of trypsin in the detection of incomplete anti-Rh antibodies. Nature 1947;159:779–81.10.1038/159779b020342442Search in Google Scholar

19Löw B. A practical method using papain and incomplete Rh-antibodies in routine Rh blood-grouping. Vox Sang (O. S.) 1955;5:94–100.Search in Google Scholar

20Haber G, Rosenfield RE. Ficin treated red cells for hemagglutination studies. In: P. H. Andresen— Papers in dedication of his 60th birthday. Copen- hagen, Denmark:Munksgaard, 1957:45–65.Search in Google Scholar

21Pirofsky B, Mangum MEJ. Use of bromelain to demonstrate erythrocyte antibodies. Proc Soc Exp Biol Med 1959;101:49–52.10.3181/00379727-101-2482813658187Search in Google Scholar

22Dodd BE, Eeles DA. Rh antibodies detectable only by enzyme technique. Immunology 1961;4:337–45.Search in Google Scholar

23Dybkjaer E. Irregular blood group antibodies. A screening test including a two-stage papain technique. Dan Med Bull 1966;13:188–92.Search in Google Scholar

24Casey FM, Dodd BE, Lincoln PJ. A study of the characteristics of certain Rh antibodies preferentially detectable by enzyme technique. Vox Sang 1972;23:493–507.10.1111/j.1423-0410.1972.tb03843.x4632942Search in Google Scholar

25Friedman BA, Oberman HA, Chadwick AR, Kindgon KI. The maximum surgical blood order schedule and surgical blood use in the United States. Transfusion 1976;16:380–7.10.1046/j.1537-2995.1976.16476247063.x951737Search in Google Scholar

26Mintz PD, Nordine RB, Henry JB, Webb WR. Expected hemotherapy in elective surgery. NY State J Med 1976;76:532–7.Search in Google Scholar

27Boral LI, Henry JB. The type and screen: a safe alternative and supplement in selected surgical procedures. Transfusion 1977;17:163–8.10.1046/j.1537-2995.1977.17277151923.x403642Search in Google Scholar

28Oberman HA, Barnes BA, Friedman BA. The risk of abbreviating the major crossmatch in urgent or massive transfusion. Transfusion 1978;18:137–41.10.1046/j.1537-2995.1978.18278160574.x417431Search in Google Scholar

29Rouault CL, Gruenhagen J. Reorganization of blood ordering practices. Transfusion 1978;18:448–53.10.1046/j.1537-2995.1978.18478251239.x684796Search in Google Scholar

30Boral LI, Hill SS, Apollon CJ, Folland A. The type and antibody screen revisited. Am J Clin Pathol 1979;71:578–81.10.1093/ajcp/71.5.578110134Search in Google Scholar

31Mintz PD, Haines AL, Sullivan MF. Incompatible crossmatch following nonreactive antibody detection test. Frequency and cause. Transfusion 1982; 22: 107–10.Search in Google Scholar

32Rouault CL. Appropriate pretransfusion testing. In: Treacy M, ed. Pretransfusion testing for the ‘80s. Washington, D. C.:AABB, 1980:125–32.Search in Google Scholar

33Spivak M. The importance of compatibility testing. In:Treacy M, ed. Pretransfusion testing for the ‘80s. Washington, D. C.:AABB, 1980:133–9.Search in Google Scholar

34Garratty G. The role of compatibility tests. Report of a meeting sponsored by the Bureau of Biologics for the Blood Products Advisory Committee. Transfusion 1982;22:169–72.10.1046/j.1537-2995.1982.22282177132.x6803410Search in Google Scholar

35Issitt PD, Anstee DJ. Applied blood group serol ogy. 4th ed. Durham, N. C.: Montgomery Scientific Publications, 1998:893–7;876.Search in Google Scholar

36Mollison PL. Blood transfusion in clinical medicine. 7th ed. Oxford, England: Blackwell Scientific Publications, 1983:541.Search in Google Scholar

37Judd WJ. Commentary: testing for unexpected red cell antibodies—two or three reagent red cell samples? Immunohematology 1997;13:90–2.10.21307/immunohematology-2019-714Search in Google Scholar

38Löw B, Messeter L. Antiglobulin test in low ionic strength salt solution for rapid antibody screening and cross-matching. Vox Sang 1974;26:53–61.10.1111/j.1423-0410.1974.tb02666.x4420622Search in Google Scholar

39Leikola J, Perkins HA. Red cell antibodies and low ionic strength: a study with enzyme-linked antiglobulin test. Transfusion 1980;20:224–8.10.1046/j.1537-2995.1980.20280169966.x6768174Search in Google Scholar

40Pinkerton PH, Zuber ED, Barr RM, et al. Sensitivity of routine blood bank methods for the detection of anti-D as determined during proficiency testing. Am J Clin Pathol 1984;82:326–9.10.1093/ajcp/82.3.3266431798Search in Google Scholar

41Pinkerton PH, Ward J, Chan R, Coovadia AS. An evaluation of a gel technique for antibody screening compared with a conventional tube method. Transfus Med 1993;3:201–5.10.1111/j.1365-3148.1993.tb00116.xSearch in Google Scholar

42Pinkerton PH, Chan R, Ward J, Coovadia AS. Sensitivity of column agglutination technology in detecting unexpected red cell antibodies. Transfus Med 1993;3:275–9.10.1111/j.1365-3148.1993.tb00061.xSearch in Google Scholar

43Lalezari P, Jiang AF. The manual Polybrene^® test; a simple and rapid procedure for the detection of red cell antibodies. Transfusion 1980;20:206–11.10.1046/j.1537-2995.1980.20280169962.x6768173Search in Google Scholar

44Plapp FV, Sinor LT, Rachel JM, et al. A solid phase antibody screen. Am J Clin Pathol 1984;82:719–21.10.1093/ajcp/82.6.7196507384Search in Google Scholar

45Nance SJ, Garratty G. Polyethylene glycol. A new potentiator of red blood cell antigen–antibody reactions. Am J Clin Pathol 1987;87:633–5.10.1093/ajcp/87.5.6333578138Search in Google Scholar

46Lapierre Y, Rigal D, Adam J, et al. The gel test:a new way to detect red cell antigen–antibody reactions. Transfusion 1990;30:109–13.10.1046/j.1537-2995.1990.30290162894.x2305438Search in Google Scholar

47Judd WJ, Steiner EA, Oberman HA, Nance SJ. Can the reading for serologic reactivity following 37°C incubation be omitted? Transfusion 1992;32:304–8.10.1046/j.1537-2995.1992.32492263441.x1585433Search in Google Scholar

48Judd WJ, Fullen DR, Steiner EA, et al. Revisiting the issue: can the reading for serologic reactivity following 37°C incubation be omitted? Transfusion 1999;39:295–9.10.1046/j.1537-2995.1999.39399219287.x10204593Search in Google Scholar

49Issitt PD. Antibody screening: elimination of another piece of the test (editorial). Transfusion 1999; 39:229–30.10.1046/j.1537-2995.1999.39399219277.x10204583Search in Google Scholar

50Issitt PD, Combs MR, Bredehoeft SJ, et al. Lack of clinical significance of”enzyme-only”red cell antibodies. Transfusion 1993;33:284–93.10.1046/j.1537-2995.1993.33493242634.x8480348Search in Google Scholar

51Shirey RS, Boyd JS, Ness PM. Polythylene glycol versus low-ionic-strength solution in pretransfusion testing: a blinded comparison study. Transfusion 1994;34:368–70.10.1046/j.1537-2995.1994.34594249044.x8191557Search in Google Scholar

52Lown J, Willis J. Monocyte monolayer assay (MMA) reactivity of alloantibodies reacting by the manual polybrene technique but not by an antiglobulin test. Transfus Med 1995;5:281–4.10.1111/j.1365-3148.1995.tb00215.x8646292Search in Google Scholar

53Issitt PD, Combs MR, Bradshaw T. Comparison of a solid phase and polyethylene glycol (PEG) IAT method in a large transfusion service (abstract). Transfusion 1997;37(Suppl 9S):28S.Search in Google Scholar

54Combs MR, Issitt PD. Use of a solid phase method as an adjunct procedure in antibody identification (abstract).Transfusion 1997;37(Suppl 9S):31S.Search in Google Scholar

55Issitt PD, Combs MR, Booth K. Comparison of the MTS-gel and polyethylene glycol (PEG) IAT methods (abstract).Transfusion 1997;37(Suppl 9S):64S.Search in Google Scholar

56Reilly B, DePalma H, Cosgrove P, Parsi M, Grima K. Comparison between routine tube tests (LISS), PEG tube test, gel technology and solid-phase red cell adherence assays (abstract). Transfusion 1997; 37(Suppl 9S):64S.Search in Google Scholar

57Alkhashan AA, Combs MR, Issitt PD. Detection of 37°C agglutinins by polyethylene glycol (PEG)-IAT (abstract).Transfusion 1997;37(Suppl 9S):28S.Search in Google Scholar

58Malone RH, Dunsford I. The Rhesus antibody anti-E in pregnancy and blood transfusion. I.The frequency of occurrence of pure anti-E: report of 12 cases. II.The demonstration by pure anti-E serum of dosage effect of the antigen E in the presence or absence of the antigen D. Blood 1951;6:1135–46.Search in Google Scholar

59Vogt E, Krystad E, Heisto H, Myhre K. A second example of a strong anti-E reacting in vitro almost exclusively with enzyme treated E positive red cells. Vox Sang 1958;3:118–23.Search in Google Scholar

60Kissmeyer-Nielson F. The serology of 123 anti-E and 55 anti-c antibodies. Sangre 1964;9:221–6.Search in Google Scholar

61Kissmeyer-Nielsen F. Irregular blood group antibodies in 200, 000 individuals. Scand J Haematol 1965;2:331–42.10.1111/j.1600-0609.1965.tb01309.x4956224Search in Google Scholar

62Dybkjaer E. Anti-E antibodies disclosed in the period 1960–1966.Vox Sang 1967;13:446–8.10.1111/j.1423-0410.1967.tb03790.x4963688Search in Google Scholar

63Harrison J. The “naturally-occurring”anti-E. Vox Sang 1970;19:123–31.10.1111/j.1423-0410.1970.tb01504.x4992289Search in Google Scholar

64International forum. What is the best technique for the detection of red cell alloantibodies? Vox Sang 1995;69:292–300.10.1111/j.1423-0410.1995.tb02613.xSearch in Google Scholar

65Judd WJ. Modern approaches to pretransfusion test- ing. Immunohematology 1999;15:41–52.10.21307/immunohematology-2019-610Search in Google Scholar