Maternal alloanti-hr’—an absence of HDN

A 24-year old female, gravida ΠI, para ΠI, delivered a full-term infant by cesarean section. A maternal blood sample at the time of admission showed antibody in her serum that had apparent anti-e specificity and that her RBCs were e+. Further studies determined that the antibody was anti-hr^s. Cord RBCs had a negative DAT and a normal Hb level. There was no clinical evidence for increased hemolysis in the infant. We describe an hr^s+ infant with no evidence of HDN due to anti-hr⁵.