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A confusion in antibody identification: anti-D production after anti-hrB

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01. Apr. 2020

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It is well known that certain combinations of alloantibodies are frequently found together. Patients with sickle cell disease (SCD) are mostly of African ancestry, and they may make anti-hrB. A transfusion of hrB–blood is often achieved by using e–(R2R2) RBCs; it is generally believed that hrB–patients readily make anti-E or a“broad-spectrum” anti-Rh34 (-HrB). We describe two multiply transfused D+ patients with SCD and a history of anti-hrB who subsequently produced anti-D. This raises the question whether anti-hrB together with anti-D is a more common antibody combination than anti-hrB with anti-E or anti-Rh34. Immunohematology2007;23:158–60.

Sprache:
Englisch
Zeitrahmen der Veröffentlichung:
4 Hefte pro Jahr
Fachgebiete der Zeitschrift:
Medizin, Klinische Medizin, Laboratoriumsmedizin