Dental extraction in congenital factor Vll deficiency with inhibitor – a case report
Geeta Nayar
Orcid-Profil, Vijayakumar Narayana Pillai
Orcid-Profil, Sheena Mathew
Orcid-Profil und Gokul Das Menon
Orcid-Profil 
Artikel-Kategorie: Case Study
Online veröffentlicht: 30. Mai 2021
Seitenbereich: 52 - 55
DOI: https://doi.org/10.17225/jhp00177
Schlüsselwörter
© 2021 Geeta Nayar et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Background
Hereditary factor VII (FVII) deficiency is a rare bleeding disorder with autosomal recessive inheritance, and FVII deficiency with an inhibitor is extremely rare. There is sparse information in the literature on the management of tooth extraction in patients with FVII deficiency and an inhibitor.
Case description
We report the case of a five-year-old child with FVII deficiency and an inhibitor who underwent dental extraction. The child had had multiple bleeding episodes including intracranial haemorrhage and had a history of severe allergic reaction to the infusion of recombinant FVII. The tooth was extracted using lignocaine gel and the antifibrinolytic agent oral tranexamic acid.
Conclusion
The extraction of a deciduous tooth in a patient with FVII deficiency and an inhibitor was undertaken without bleeding complications. There are currently no guidelines regarding management of this type of case. Further studies and evidence are required so that management can be standardised.