Uneingeschränkter Zugang

Doppler ultrasound-based evaluation of hemodynamic changes in the ophthalmic artery and central retinal artery in patients with type 1 diabetes mellitus without retinopathy and with mild non-proliferative retinopathy


Zitieren

Fig. 1.

Flow velocity spectrum in the ophthalmic artery
Flow velocity spectrum in the ophthalmic artery

Fig. 2.

Flow velocity spectrum in the central retinal artery
Flow velocity spectrum in the central retinal artery

Statistical relationships of blood flow parameters in the OA and CRA between the control and type 1 diabetes groups

Variable Study group Control group p
n median 25–75 P n median 25–75 P
OA PSV 80 33.9 from 28.950 to 39.950 80 34.4 from 29.05 to 40.10 0.985
OA EDV 79 7.3 from 5.900 to 10.675 79 8.6 from 6.65 to 10.10 0.1376
OA RI 79 0.78 from 0.712 to 0.810 80 0.75 from 0.73 to 0.77 0.0805
CRA PSV 80 10.5 from 8.700 to 11.900 80 11.1 from 10.30 to 12.00 0.0064
CRA EDV 80 3 from 2.400 to 3.700 80 3.8 from 3.30 to 4.35 <0.0001
CRA RI 80 0.7 from 0.650 to 0.740 80 0.65 from 0.62 to 0.68 <0.0001

Detailed descriptive statistics for blood flow parameters (PSV, EDV, RI in the OA and CRA) in the control group

Variable N Min. Max. Median 25–75 P
OA PSV 80 20.1 54.3 34.4 from 29.05 to 40.10
OA EDV 79 4.3 15.1 8.6 from 6.65 to 10.10
OA RI 80 0.6 0.83 0.75 from 0.73 to 0.77
CRA PSV 80 8.7 14.5 11.1 from 10.30 to 12.00
CRA EDV 80 1.9 5.7 3.8 from 3.30 to 4.35
CRA RI 80 0.52 0.75 0.65 from 0.62 to 0.68

Detailed descriptive statistics for blood flow parameters (PSV, EDV, RI in the CRA) in the group with type 1 diabetes mellitus

Variable N Min. Max. Median 25–75 P
CRA PSV 80 6 14.7 10.5 from 8.70 to 11.90
CRAEDV 80 1.5 5.3 3 from 2.40 to 3.70
CRA RI 80 0.55 0.82 0.7 from 0.65 to 0.74

Descriptive statistics for blood flow parameters in the OA in the group with type 1 diabetes mellitus

Variable N Min. Max. Median 25–75 P
OA PSV 80 17.9 73.9 33.9 from 28.95 to 39.95
OA EDV 79 3.2 27.7 7.3 from 5.90 to 10.67
OA RI 79 0.55 0.9 0.78 from 0.71 to 0.81

Statistical comparison of blood flow parameters in the OA and CRA in the group with type 1 diabetes mellitus depending on the degree of diabetes control (HbA1c)

Variable >7% <7% p
n median 25–75 P n median 25–75 P
OA PSV 46 31.3 from 26.50 to 36.30 34 37.8 from 32.90 to 43.40 0.0024
OA EDV 46 6.8 from 5.80 to 9.20 33 9 from 6.25 to 11.82 0.0514
OA RI 46 0.78 from 0.70 to 0.82 33 0.76 from 0.72 to 0.81 0.7959
CRA PSV 46 9.7 from 8.10 to 11.10 34 11.45 from 9.50 to 12.00 0.0382
CRA EDV 46 2.8 from 2.30 to 3.60 34 3.25 from 2.70 to 3.70 0.0679
CRA RI 46 0.695 from 0.64 to 0.74 34 0.7 from 0.65 to 0.73 0.9418

Statistical comparison of blood flow parameters in the OA and CRA in the group with type 1 diabetes mellitus depending on the presence of mild non-proliferative retinopathy

Variable No retinopathy Retinopathy p
n median 25–75 P n median 25–75 P
OA PSV 65 34.2 from 29.42 to 40.00 15 33.9 from 25.82 to 37.17 0.321
OA EDV 64 7.4 from 5.85 to 10.50 15 7.2 from 6.30 to 11.20 0.822
OA RI 64 0.78 from 0.72 to 0.82 15 0.75 from 0.69 to 0.79 0.220
CRA PSV 65 10.7 from 9.22 to 12.00 15 8 from 6.92 to 10.87 0.016
CRA EDV 65 3.2 from 2.50 to 3.72 15 2.7 from 2.20 to 2.97 0.024
CRA RI 65 0.7 from 0.64 to 0.74 15 0.7 from 0.65 to 0.72 0.917
eISSN:
2451-070X
Sprache:
Englisch
Zeitrahmen der Veröffentlichung:
4 Hefte pro Jahr
Fachgebiete der Zeitschrift:
Medizin, Vorklinische Medizin, Grundlagenmedizin, andere