<abstract xmlns="http://www.w3.org/1999/xhtml"><sec id="j_sjph-2016-0016_s_355_w2aab3b8b6b1b7b1aab1c15b1Aa"><h3>Background</h3><p>Colorectal polyps (CP) are common among individuals older than 50 years. Some polyp types can precede colorectal cancer (CRC). This study aimed at describing histopathological characteristics of colorectal polyps in relation to age and gender among symptomatic patients referred for a colonoscopy examination during 2011-2014 in Tirana, Albania.</p></sec><sec id="j_sjph-2016-0016_s_356_w2aab3b8b6b1b7b1aab1c15b2Aa"><h3>Methods</h3><p>Study population included 267 individuals aged ≥ 20 years and diagnosed with ≥ 1 polyp during a colonoscopy examination. A total of 346 polyps were identified, excised and measured, and underwent histopathological examination.</p></sec><sec id="j_sjph-2016-0016_s_358_w2aab3b8b6b1b7b1aab1c15b3Aa"><h3>Results</h3><p>Adenomas accounted for 79.8% of all polyps and tubular type was the most frequent one (74.4%). The majority of polyps (42.5%) were small (&lt;1 cm), 38.7% of a medium size (1-2 cm) and 18.8% large (>2 cm). Adenomas were larger than non-adenomatous polyps (p&lt;0.01)</p><p>There was no gender difference with regard to patient age (p=0.22) or polyp size (p=0.84) Adenomas were more frequent among men compared to women (p=0.02). Age was strongly related to polyp characteristics. The proportion of adenomas increased significantly with age (p&lt;0.01). Within adenomas, the proportion of villous types - a precursor of colorectal cancer - increased remarkably with age (p=0.01). Older age was positively associated with potentially malignant adenomas (defined as adenomas > 1 cm and showing high-grade dysplasia) (p&lt;0.01).</p></sec><sec id="j_sjph-2016-0016_s_359_w2aab3b8b6b1b7b1aab1c15b4Aa"><h3>Conclusion</h3><p>Adenomas accounted for the majority of polyps. Their morphology, size and malignant potential were related to patient age.</p></sec></abstract>

BackgroundColorectal polyps (CP) are common among individuals older than 50 years. Some polyp types can precede colorectal cancer (CRC). This study aimed at describing histopathological characteristics of colorectal polyps in relation to age and gender among symptomatic patients referred for a colonoscopy examination during 2011-2014 in Tirana, Albania.MethodsStudy population included 267 individuals aged ≥ 20 years and diagnosed with ≥ 1 polyp during a colonoscopy examination. A total of 346 polyps were identified, excised and measured, and underwent histopathological examination.ResultsAdenomas accounted for 79.8% of all polyps and tubular type was the most frequent one (74.4%). The majority of polyps (42.5%) were small (<1 cm), 38.7% of a medium size (1-2 cm) and 18.8% large (>2 cm). Adenomas were larger than non-adenomatous polyps (p<0.01)There was no gender difference with regard to patient age (p=0.22) or polyp size (p=0.84) Adenomas were more frequent among men compared to women (p=0.02). Age was strongly related to polyp characteristics. The proportion of adenomas increased significantly with age (p<0.01). Within adenomas, the proportion of villous types - a precursor of colorectal cancer - increased remarkably with age (p=0.01). Older age was positively associated with potentially malignant adenomas (defined as adenomas > 1 cm and showing high-grade dysplasia) (p<0.01).ConclusionAdenomas accounted for the majority of polyps. Their morphology, size and malignant potential were related to patient age.

Demographic And Histopathological Characteristics Of Colorectal Polyps: A Descriptive Study Based On Samples Obtained From Symptomatic Patients

University Hospital Center “Mother Teresa”, Department of Pathology, Rruga e Dibrës 372, Tirana,

Endoscopic Clinic “La Vita”, Rruga ‘Xhanfize Keko’ 13, Tirana,

University Hospital Center “Mother Teresa”, Department of Surgery, Rruga e Dibrës 372, Tirana,

University of Bergen, Faculty of Medicine and Dentistry, Department of Global Public Health and Primary Care, Kalfarveien 31, Bergen, 5018,

Slovenian Journal of Public Health

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

DEMOGRAFSKE IN HISTOPATOLOŠKE ZNAČILNOSTI KOLOREKTALNIH POLIPOV: DESKRIPTIVNA RAZISKAVA NA OSNOVI VZORCEV, PRIDOBLJENIH OD SIMPTOMATSKIH PACIENTOV

BackgroundColorectal polyps (CP) are common among individuals older than 50 years. Some polyp types can precede colorectal cancer (CRC). This study aimed at describing histopathological characteristics of colorectal polyps in relation to age and gender among symptomatic patients referred for a colonoscopy examination during 2011-2014 in Tirana, Albania.MethodsStudy population included 267 individuals aged ≥ 20 years and diagnosed with ≥ 1 polyp during a colonoscopy examination. A total of 346 polyps were identified, excised and measured, and underwent histopathological examination.ResultsAdenomas accounted for 79.8% of all polyps and tubular type was the most frequent one (74.4%). The majority of polyps (42.5%) were small (2 cm). Adenomas were larger than non-adenomatous polyps (p 1 cm and showing high-grade dysplasia) (p<0.01).ConclusionAdenomas accounted for the majority of polyps. Their morphology, size and malignant potential were related to patient age.

BackgroundColorectal polyps (CP) are common among individuals older than 50 years. Some polyp types can precede colorectal cancer (CRC). This study aimed at...

Demographic And Histopathological Characteristics Of Colorectal Polyps: A Descriptive Study Based On Samples Obtained From Symptomatic Patients

Article Category: Original scientific article

Online veröffentlicht: 11. Feb. 2016

Seitenbereich: 118 - 123

Eingereicht: 12. Aug. 2015

Akzeptiert: 26. Dez. 2015

DOI: https://doi.org/10.1515/sjph-2016-0016

Schlüsselwörter
colorectal polyp, epidemiology, colonoscopy examination, Albania

© National Institute of Public Health, Slovenia

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Demographic And Histopathological Characteristics Of Colorectal Polyps: A Descriptive Study Based On Samples Obtained From Symptomatic Patients

Article Category: Original scientific article

Online veröffentlicht: 11. Feb. 2016

Seitenbereich: 118 - 123

Eingereicht: 12. Aug. 2015

Akzeptiert: 26. Dez. 2015

DOI: https://doi.org/10.1515/sjph-2016-0016

Schlüsselwörtercolorectal polyp, epidemiology, colonoscopy examination, Albania

© National Institute of Public Health, Slovenia

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Schlüsselwörter
colorectal polyp, epidemiology, colonoscopy examination, Albania