<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Gardner syndrome is a rare autosomal-dominant genetic disorder, considered a variant of familial adenomatous polyposis. It is characterized by intestinal polyposis and various bone and soft-tissue tumors, including osteomas, epidermal and dermal cysts, lipomas and fibromas. Intestinal polyps have high potential to become malignant, and the screening of intestinal lesions is mandatory. Maxillofacial manifestations, such as jaw osteomas, odontomas, dental abnormalities and soft tissue tumors frequently precede the intestinal manifestations. Thus, maxillofacial surgeons and dental practitioners may have important role in early detection of Gardner syndrome. In this case report we present a 22 year old male patient who was reffered to maxillofacial surgeon due to osteoma of the mandible. After obtaining clinical and radiological examinations, as well as data from family history, Gardner syndrome was suspected, which was later confirmed after gastroenterological examination.</p></abstract>

Gardner syndrome is a rare autosomal-dominant genetic disorder, considered a variant of familial adenomatous polyposis. It is characterized by intestinal polyposis and various bone and soft-tissue tumors, including osteomas, epidermal and dermal cysts, lipomas and fibromas. Intestinal polyps have high potential to become malignant, and the screening of intestinal lesions is mandatory. Maxillofacial manifestations, such as jaw osteomas, odontomas, dental abnormalities and soft tissue tumors frequently precede the intestinal manifestations. Thus, maxillofacial surgeons and dental practitioners may have important role in early detection of Gardner syndrome. In this case report we present a 22 year old male patient who was reffered to maxillofacial surgeon due to osteoma of the mandible. After obtaining clinical and radiological examinations, as well as data from family history, Gardner syndrome was suspected, which was later confirmed after gastroenterological examination.

The Surgical Management of Gardner Syndrome Manifestation in the Maxillofacial Region: A Case Report

Clinic for Maxillofacial surgery, Military Medical Academy

Experimental and Applied Biomedical Research (EABR)

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Gardner syndrome is a rare autosomal-dominant genetic disorder, considered a variant of familial adenomatous polyposis. It is characterized by intestinal...

The Surgical Management of Gardner Syndrome Manifestation in the Maxillofacial Region: A Case Report

Online veröffentlicht: 16. Mai 2019

Seitenbereich: 89 - 91

Eingereicht: 20. Juni 2017

Akzeptiert: 13. Juli 2017

DOI: https://doi.org/10.1515/sjecr-2017-0038

Schlüsselwörter
gardner syndrome, extraintestinal manifestation, mandible osteoma, treatment

© 2019 Slobodan Loncarevic et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The Surgical Management of Gardner Syndrome Manifestation in the Maxillofacial Region: A Case Report

Online veröffentlicht: 16. Mai 2019

Seitenbereich: 89 - 91

Eingereicht: 20. Juni 2017

Akzeptiert: 13. Juli 2017

DOI: https://doi.org/10.1515/sjecr-2017-0038

Schlüsselwörtergardner syndrome, extraintestinal manifestation, mandible osteoma, treatment

© 2019 Slobodan Loncarevic et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Schlüsselwörter
gardner syndrome, extraintestinal manifestation, mandible osteoma, treatment