[1. Kannel WB, McGee D, Gordon T. A general cardiovascular risk profile: the Framingham Study. Am J Cardiol. 1976; 38(1):46-51. DOI: 10.1016/0002-9149(76)90061-8.10.1016/0002-9149(76)90061-8]Search in Google Scholar
[2. Rodriguez-Fernandez R, Rahajeng E, Viliani F, Kushadiwijaya H, Amiya RM, Bangs MJ. Noncommunicable disease risk factor patterns among mining industry workers in Papua, Indonesia: longitudinal findings from the Cardiovascular Outcomes in a Papuan Population and Estimation of Risk (COPPER) Study. Occup Environ Med. 2015;72(10):728-35. DOI: 10.1136/oemed-2014-102664.10.1136/oemed-2014-102664]Search in Google Scholar
[3. Ross R. Atherosclerosis—an inflammatory disease. N Engl J Med. 1999;340(2): 115-26. DOI: 10.1056/NEJM199901143400207.10.1056/NEJM199901143400207]Search in Google Scholar
[4. Zand Parsa A, Ashoori S, Abdollahi A. The Effect of Two Different Doses of Atorvastatin on Lipoprotein-a on Patients with Acute Coronary Syndrome. Iranian Journal of Pathology. 2012;7:101–6.]Search in Google Scholar
[5. LaRosa JC, Grundy SM, Waters DD, Shear C, Barter P, Fruchart JC, et al. Treating to New Targets (TNT) Investigators. Intensive lipid lowering with atorvastatin in patients with stable coronary disease. N Engl J Med. 2005; 352(14):1425-35. DOI: 10.1056/NEJMoa050461.10.1056/NEJMoa050461]Search in Google Scholar
[6. Brown MS, Goldstein JL. Multivalent feedback regulation of HMG CoA reductase, a control mechanism coordinating isoprenoid synthesis and cell growth. J Lipid Res. 1980;21(5):505-17.10.1016/S0022-2275(20)42221-7]Search in Google Scholar
[7. Carbonell T, Freire E. Binding thermodynamics of statins to HMG-CoA reductase. Biochemistry. 2005; 44(35):11741-8. DOI: 10.1021/bi050905v.10.1021/bi050905v16128575]Search in Google Scholar
[8. Friesen JA, Rodwell VW. The 3-hydroxy-3-methylglutaryl coenzyme-A (HMG-CoA) reductases. Genome Biol. 2004; 5(11):248. DOI: 10.1186/gb-2004-5-11-248.10.1186/gb-2004-5-11-24854577215535874]Search in Google Scholar
[9. Maron DJ, Fazio S, Linton MF. Current perspectives on statins. Circulation. 2000;101(2):207-13. DOI: 10.1161/01.CIR.101.2.207.10.1161/01.CIR.101.2.207]Search in Google Scholar
[10. Varghese GK, Bose LV, Habtemariam S. Antidiabetic components of Cassia alata leaves: identification through α-glucosidase inhibition studies. Pharm Biol. 2013;51(3):345-9. DOI: 10.3109/13880209.2012.729066.10.3109/13880209.2012.72906623137344]Search in Google Scholar
[11. Jaydeokar AV, Bandawane DD, Bibave KH, Patil TV. Hepatoprotective potential of Cassia auriculata roots on ethanol and antitubercular drug-induced hepatotoxicity in experimental models. Pharm Biol. 2014;52(3):344-55. DOI: 10.3109/13880209.2013.837075.10.3109/13880209.2013.83707524472085]Search in Google Scholar
[12. Mondal A, Karan SK, Singha T, Rajalingam D, Maity TK. Evaluation of Hepatoprotective Effect of Leaves of Cassia sophera Linn. Evid Based Complement Alternat Med. 2012; 2012:436139. DOI: 10.1155/2012/436139.10.1155/2012/436139336833522690244]Search in Google Scholar
[13. Cho IJ, Lee C, Ha TY. Hypolipidemic effect of soluble fiber isolated from seeds of Cassia tora Linn. in rats fed a high-cholesterol diet. J Agric Food Chem. 2007;55(4):1592-6. DOI: 10.1021/jf0622127.10.1021/jf062212717300158]Search in Google Scholar
[14. Zhang JD, Hu YJ, Zhang W, Huang XA, Zhang HL. Chemical Constituents of Cassia mimosoides Linn. Journal of Tropical and Subtropical Botany. 2009;17:80-2.]Search in Google Scholar
[15. Jung KA, Song TC, Han D, Kim IH, Kim YE, Lee CH. Cardiovascular protective properties of kiwifruit extracts in vitro. Biol Pharm Bull. 2005; 28(9):1782-5. DOI: 10.1248/bpb.28.1782.10.1248/bpb.28.178216141561]Search in Google Scholar
[16. Schointuch MN, Gilliam TP, Stine JE, Han X, Zhou C, Gehrig PA, Kim K, Bae-Jump VL. Simvastatin, an HMG-CoA reductase inhibitor, exhibits anti-metastatic and anti-tumorigenic effects in endometrial cancer. Gynecol Oncol. 2014;134(2): 346-55. DOI: 10.1016/j.ygyno.2014.05.015.10.1016/j.ygyno.2014.05.015412553624880141]Search in Google Scholar
[17. Soares RA, Mendonça S, de Castro LÍ, Menezes AC, Arêas JA. Major peptides from amaranth (Amaranthus cruentus) protein inhibit HMG-CoA reductase activity. Int J Mol Sci. 2015;16(2): 4150-60. DOI: 10.3390/ijms16024150.10.3390/ijms16024150434694925690031]Search in Google Scholar
[18. Nagy G, Farkas A, Csernetics Á, Bencsik O, Szekeres A, Nyilasi I, Vágvölgyi C, Papp T. Transcription of the three HMG-CoA reductase genes of Mucor circinelloides. MC Microbiol. 2014;14:93. DOI: 10.1186/1471-2180-14-93.10.1186/1471-2180-14-93403742724731286]Search in Google Scholar
[19. Wang GY, Keasling JD. Amplification of HMG-CoA reductase production enhances carotenoid accumulation in Neurospora crassa. Metab Eng. 2002;4(3): 193-201. DOI: 10.1006/mben.2002.0225.10.1006/mben.2002.022512616689]Search in Google Scholar
[20. Burg JS, Espenshade PJ. Regulation of HMG-CoA reductase in mammals and yeast. Prog Lipid Res. 2011; 50(4): 403-10. DOI: 10.1016/j.plipres.2011.07.002.10.1016/j.plipres.2011.07.002318431321801748]Search in Google Scholar
[21. Wang X, Guan L, Zhao Y, Lei L, Liu Y, Ma KY, Wang L, Man SW, Wang J, Huang Y, Chen ZY. Plasma cholesterol-lowering activity of dietary dihydrocholesterol in hypercholesterolemia hamsters. Atherosclerosis. 2015; 242(1):77-86. DOI: 10.1016/j.atherosclerosis.2015.06.046.10.1016/j.atherosclerosis.2015.06.04626184696]Search in Google Scholar
[22. Wang W, He Y, Lin P, Li Y, Sun R, Gu W, Yu J, Zhao R. In vitro effects of active components of Polygonum Multiflorum Radix on enzymes involved in the lipid metabolism. J Ethnopharmacol. 2014;153(3):763-70. DOI: 10.1016/j.jep.2014.03.042.10.1016/j.jep.2014.03.04224680992]Search in Google Scholar
[23. Yan GL, Wen KR, Duan CQ. Enhancement of β-carotene production by over-expression of HMG-CoA reductase coupled with addition of ergosterol biosyn-thesis inhibitors in recombinant Saccharomyces cerevisiae. Curr Microbiol. 2012;64(2): 159-63. DOI: 10.1007/s00284-011-0044-9.10.1007/s00284-011-0044-922086347]Search in Google Scholar
[24. Han L, Lai P, Du JR. Deciphering molecular mechanism underlying hypolipidemic activity of echinocystic Acid. Evid Based Complement Alternat Med. 2014; 2014:823154. DOI: 10.1155/2014/823154.10.1155/2014/823154394228724669228]Search in Google Scholar
[25. Sá C, Oliveira AR, Machado C, Azevedo M, Pereira-Wilson C. Effects on Liver Lipid Metabolism of the Naturally Occurring Dietary Flavone Luteolin-7-glucoside. Evid Based Complement Alternat Med. 2015;2015:647832. DOI: 10.1155/2015/647832.10.1155/2015/647832446576926113868]Search in Google Scholar