Uneingeschränkter Zugang

IL-17 and Th17 cells in systemic sclerosis: a comprehensive review


Zitieren

1. GRAEBER KE, OLSEN NJ. Th17 cell cytokine secretion profile in host defense and autoimmunity. Inflamm Res. 2012; 61 (2):87-96.10.1007/s00011-011-0419-1Open DOISearch in Google Scholar

2. HYMOWITZ SG, FILVAROFF EH, YIN JP, LEE J, CAI L, RISSER P, et al. IL-17s adopt a cystine knot fold: structure and activity of a novel cytokine, IL-17F, and implications for receptor binding. EMBO J. 2001; 20:5332–41.10.1093/emboj/20.19.5332Open DOISearch in Google Scholar

3. TANASESCU C, BĂLĂNESCU E, BĂLĂNESCU P, OLTEANU R, BADEA C, GRANCEA C, et al. IL-17 in cutaneous lupus erythematosus. Eur J Intern Med. 2010; 21 (3):202-7.10.1016/j.ejim.2010.03.004Open DOISearch in Google Scholar

4. BLAUVELT A. T-helper 17 cells in psoriatic plaques and additional genetic links between IL-23 and psoriasis. J Invest Dermatol. 2008; 128 (5):1064-7.10.1038/jid.2008.85Search in Google Scholar

5. CHEN DY, CHEN YM, LAN JL, LIN CC, CHEN HH, HSIEH CW. Potential role of Th17cells in the pathogenesis of adult-onset Still’s disease. Rheumatology (Oxford). 2010; 49 (12):2305-12.10.1093/rheumatology/keq284Search in Google Scholar

6. DE NITTO D, SARRA M, CUPI ML, PALLONE F, MONTELEONE G. Targeting IL-23 and Th17-cytokines in inflammatory bowel diseases. Curr Pharm Des. 2010; 16 (33):3656-60.10.2174/138161210794079164Search in Google Scholar

7. ZHANG L, LI YG, LI YH, QI L, LIU XG, YUAN CZ, et al. Increased frequencies of Th22 cells as well as Th17 cells in the peripheral blood of patients with ankylosing spondylitis and rheumatoid arthritis. PLoS One. 2012; 7 (4):e31000.10.1371/journal.pone.0031000Search in Google Scholar

8. RAYCHAUDHURI SP, RAYCHAUDHURI SK. IL-23/IL-17 axis in spondyloarthritis-bench to bedside. Clin Rheumatol. 2016; 35 (6):1437-41.10.1007/s10067-016-3263-4Search in Google Scholar

9. LUBRANO E, PERROTTA FM. Secukinumab for ankylosing spondylitis and psoriatic arthritis. Ther Clin Risk Manag. 2016; 12:1587-92.10.2147/TCRM.S100091Search in Google Scholar

10. KURASAWA K, HIROSE K, SANO H, ENDO H, SHINKAI H, NAWATA Y, et al. Increased interleukin-17 production in patients with systemic sclerosis. Arthritis Rheum. 2000; 43 (11):2455-63.10.1002/1529-0131(200011)43:11<2455::AID-ANR12>3.0.CO;2-KSearch in Google Scholar

11. MURATA M, FUJIMOTO M, MATSUSHITA T, HAMAGUCHI Y, HASEGAWA M, TAKEHARA K, et al. Clinical association of serum interleukin-17 levels in systemic sclerosis: is systemic sclerosis a Th17 disease? J Dermatol Sci. 2008; 50(3):240-2.10.1016/j.jdermsci.2008.01.00118329249Open DOISearch in Google Scholar

12. GOURH P, ARNETT FC, ASSASSI S, TAN FK, HUANG M, DIEKMAN L, et al. Plasma cytokine profiles in systemic sclerosis: associations with autoantibody subsets and clinical manifestations. Arthritis Res Ther, 2009; 11 (5):R147.10.1186/ar2821278725919799786Open DOISearch in Google Scholar

13. HIGGS BW, ZHU W, RICHMAN L, FIORENTINO DF, GREENBERG SA, JALLAL B, et al. Identification of activated cytokine pathways in the blood of systemic lupus erythematosus, myositis, rheumatoid arthritis, and scleroderma patients. Int J Rheum Dis. 2012; 15 (1):25-35.10.1111/j.1756-185X.2011.01654.x22324944Open DOISearch in Google Scholar

14. TOROK KS, KURZINSKI K, KELSEY C, YABES J, MAGEE K, VALLEJO AN, et al. Peripheral blood cytokine and chemokine profiles in juvenile localized scleroderma: T-helper cell-associated cytokine profiles. Semin Arthritis Rheum. 2015; 45 (3):284-93.10.1016/j.semarthrit.2015.06.006465612526254121Search in Google Scholar

15. OLEWICZ-GAWLIK A, DANCZAK-PAZDROWSKA A, KUZNAR-KAMINSKA B, GORNOWICZ-POROWSKA J, KATULSKA K, TRZYBULSKA D, et al. Interleukin-17 and interleukin-23: importance in the pathogenesis of lung impairment in patients with systemic sclerosis. Int J Rheum Dis. 2014; 17 (6):664-70.10.1111/1756-185X.1229024467649Open DOISearch in Google Scholar

16. BĂLĂNESCU P, LĂDARU A, BĂLĂNESCU E, NICOLAU A, BĂICUŞ C, DAN GA. IL-17, IL-6 and IFN-γ in Systemic Sclerosis Patients. Rom J Intern Med. 2015; 53 (1):44-9.10.1515/rjim-2015-000626076560Search in Google Scholar

17. OKAMOTO Y, HASEGAWA M, MATSUSHITA T, HAMAGUCHI Y, HUU DL, IWAKURA Y, et al. Potential roles of interleukin-17A in the development of skin fibrosis in mice. Arthritis Rheum. 2012; 64 (11):3726-35.10.1002/art.3464322833167Open DOISearch in Google Scholar

18. LEI L, HE ZY, ZHAO C, SUN XJ, ZHONG XN. Elevated frequencies of CD4(+) IL-21(+) T, CD4(+) IL-21R(+) T and IL-21 (+) Th17 cells, and increased levels of IL-21 in bleomycin-induced mice may be associated with dermal and pulmonary inflammation and fibrosis. Int J Rheum Dis. 2016; 19 (4):392-404.10.1111/1756-185X.1252225545680Search in Google Scholar

19. LEI L, ZHONG XN, HE ZY, ZHAO C, SUN XJ. IL-21 induction of CD4+ T cell differentiation into Th17 cells contributes to bleomycin-induced fibrosis in mice. Cell Biol Int. 2015; 39 (4):388-99.10.1002/cbin.1041025492803Search in Google Scholar

20. RADSTAKE TR, VAN BON L, BROEN J, HUSSIANI A, HESSELSTRAND R, WUTTGE DM, et al. The pronounced Th17 profile in systemic sclerosis (SSc) together with intracellular expression of TGFbeta and IFNgamma distinguishes SSc phenoltypes. PLoS One. 2009; 4 (6):e5903.10.1371/journal.pone.0005903269199119536281Search in Google Scholar

21. FENOGLIO D, BATTAGLIA F, PARODI A, STRINGARA S, NEGRINI S, PANICO N, RIZZI M, et al. Alteration of Th17 and Treg cell subpopulations co-exist in patients affected with systemic sclerosis. Clin Immunol. 2011; 139 (3):249-57.10.1016/j.clim.2011.01.01321419712Search in Google Scholar

22. PAPP G, HORVATH IF, BARATH S, GYIMESI E, SIPKA S, SZODORAY P, et al. Altered T-cell and regulatory cell repertoire in patients with diffuse cutaneous systemic sclerosis. Scand J Rheumatol. 2011; 40 (3):205-10.10.3109/03009742.2010.52802121366383Search in Google Scholar

23. TRUCHETET ME, BREMBILLA NC, MONTANARI E, ALLANORE Y, CHIZZOLINI C. Increased frequency of circulating Th22 in addition to Th17 and Th2 lymphocytes in systemic sclerosis: association with interstitial lung disease. Arthritis Res Ther. 2011; 13(5):R166.10.1186/ar3486330810021996293Open DOISearch in Google Scholar

24. ALMANZAR G, KLEIN M, SCHMALZING M, HILLIGARDT D, EL HAJJ N, KNEITZ H, et al. Disease manifestation and inflammatory activity as modulators of Th17/Treg balance and RORC/FoxP3 Methylation in Systemic Sclerosis. Int Arch Allergy Immunol. 2016; 171(2):141-54.10.1159/00045094927902985Search in Google Scholar

25. RODRÍGUEZ-REYNA TS, FURUZAWA-CARBALLEDA J, CABIEDES J, FAJARDO-HERMOSILLO LD, MARTÍNEZ-REYES C, DÍAZ-ZAMUDIO M, et al. Th17 peripheral cells are increased in diffuse cutaneous systemic sclerosis compared with limited illness: a cross-sectional study. Rheumatol Int. 2012; 32 (9):2653-60.10.1007/s00296-011-2056-y21789610Open DOISearch in Google Scholar

26. LIU X, GAO N, LI M, XU D, HOU Y, WANG Q, et al. Elevated levels of CD4(+)CD25(+)FoxP3(+) T cells in systemic sclerosis patients contribute to the secretion of IL-17 and immunosuppression dysfunction. PLoS One. 2013; 8 (6):e64531.10.1371/journal.pone.0064531367912823776439Search in Google Scholar

27. FURUZAWA-CARBALLEDA J, ORTÍZ-ÁVALOS M, LIMA G, JURADO-SANTA CRUZ F, LLORENTE L. Subcutaneous administration of polymerized type I collagen downregulates interleukin (IL)-17A, IL-22 and transforming growth factor-β1 expression, and increases FoxP3-expressing cells in localized scleroderma. Clin Exp Dermatol. 2012; 37 (6):599-609.10.1111/j.1365-2230.2012.04385.x22731679Search in Google Scholar

28. NAKASHIMA T, JINNIN M, YAMANE K, HONDA N, KAJIHARA I, MAKINO T, MASUGUCHI S, et al. Impaired IL-17 signaling pathway contributes to the increased collagen expression in scleroderma fibroblasts. J Immunol. 2012; 188 (8):3573-83.10.4049/jimmunol.110059122403442Search in Google Scholar

29. LONATI PA, BREMBILLA NC, MONTANARI E, FONTAO L, GABRIELLI A, VETTORI S, et al. High IL-17E and low IL-17C dermal expression identifies a fibrosis-specific motif common to morphea and systemic sclerosis. PLoS One. 2014; 9 (8):e105008.10.1371/journal.pone.0105008413815225136988Search in Google Scholar

30. BREMBILLA NC, MONTANARI E, TRUCHETET ME, RASCHI E, MERONI P, CHIZZOLINI C. Th17 cells favor inflammatory responses while inhibiting type I collagen deposition by dermal fibroblasts: differential effects in healthy and systemic sclerosis fibroblasts. Arthritis Res Ther. 2013; 15 (5):R151.10.1186/ar4334397912324289089Open DOISearch in Google Scholar

31. FRECH TM, REVELO MP, DRAKOS SG, MURTAUGH MA, MARKEWITZ BA, SAWITZKE AD, LI DY. Vascular leak is a central feature in the pathogenesis of systemic sclerosis. J Rheumatol 2012; 39:1385-91.10.3899/jrheum.111380364027222660809Search in Google Scholar

32. LIU M, YANG J, XING X, CUI X, LI M. Interleukin-17A promotes functional activation of systemic sclerosis patient-derived dermal vascular smooth muscle cells by extracellular-regulated protein kinases signalling pathway. Arthritis Res Ther. 2014; 16 (6):4223.10.1186/s13075-014-0512-2431676525551434Open DOISearch in Google Scholar

33. XING X, YANG J, YANG X, WEI Y, ZHU L, GAO D, et al. IL-17A induces endothelial inflammation in systemic sclerosis via the ERK signaling pathway. PLoS One. 2013; 8 (12):e85032.10.1371/journal.pone.0085032387163324376862Search in Google Scholar

34. YANG X, YANG J, XING X, WAN L, LI M. Increased frequency of Th17 cells in systemic sclerosis is related to disease activity and collagen overproduction. Arthritis Res Ther. 2014; 16 (1):R4.10.1186/ar4430397914224398084Search in Google Scholar

35. ZHOU Y, HOU W, XU K, HAN D, JIANG C, MOU K, et al. The elevated expression of Th17-related cytokines and receptors is associated with skin lesion severity in early systemic sclerosis. Hum Immunol. 2015; 76 (1):22-9.10.1016/j.humimm.2014.12.00825500255Search in Google Scholar

36. MELONI F, SOLARI N, CAVAGNA L, MOROSINI M, MONTECUCCO CM, FIETTA AM. Frequency of Th1, Th2 and Th17 producing T lymphocytes in bronchoalveolar lavage of patients with systemic sclerosis. Clin Exp Rheumatol. 2009; 27 (5):765-72.Search in Google Scholar

37. ROLLA G, FUSARO E, NICOLA S, BUCCA C, PERONI C, PARISI S, et al. Th-17 cytokines and interstitial lung involvement in systemic sclerosis. J Breath Res. 2016; 10 (4):046013.10.1088/1752-7155/10/4/04601327869103Search in Google Scholar

38. HSU E, SHI H, JORDAN RM, LYONS-WEILER J, PILEWSKI JM, FEGHALI-BOSTWICK CA. Lung tissues in patients with systemic sclerosis have gene expression patterns unique to pulmonary fibrosis and pulmonary hypertension. Arthritis Rheum. 2011; 63 (3):783-94.10.1002/art.30159313981821360508Open DOISearch in Google Scholar

39. FAVA A, CIMBRO R, WIGLEY FM, LIU QR, ROSEN A, BOIN F. Frequency of circulating topoisomerase-I-specific CD4 T cells predicts presence and progression of interstitial lung disease in scleroderma. Arthritis Res Ther. 2016; 18 (1):9.10.1186/s13075-016-0993-2485729327145754Open DOISearch in Google Scholar

eISSN:
2501-062X
Sprache:
Englisch
Zeitrahmen der Veröffentlichung:
4 Hefte pro Jahr
Fachgebiete der Zeitschrift:
Medizin, Klinische Medizin, Allgemeinmedizin, Innere Medizin, andere, Kardiologie, Gastroenterologie, Rheumatologie