Malignant gliomas: old and new systemic treatment approaches
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23. Apr. 2016
Über diesen Artikel
Artikel-Kategorie: Review
Online veröffentlicht: 23. Apr. 2016
Seitenbereich: 129 - 138
Eingereicht: 30. Juni 2014
Akzeptiert: 29. Sept. 2014
DOI: https://doi.org/10.1515/raon-2015-0003
Schlüsselwörter
© 2016 Radiol Oncol
This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Background
Malignant (high-grade) gliomas are rapidly progressive brain tumours with very high morbidity and mortality. Until recently, treatment options for patients with malignant gliomas were limited and mainly the same for all subtypes of malignant gliomas. The treatment included surgery and radiotherapy. Chemotherapy used as an adjuvant treatment or at recurrence had a marginal role.
Conclusions
Nowadays, the treatment of malignant gliomas requires a multidisciplinary approach. The treatment includes surgery, radiotherapy and chemotherapy. The chosen approach is more complex and individually adjusted. By that, the effect on the survival and quality of life is notable higher.