Optimization, Validation and Application of UV-Vis Spectrophotometric-Colorimetric Methods for Determination of Trimethoprim in Different Medicinal Products

1. Fresta, M., Furneri, P.M., Mezzasalma, E., Nicolosi, V.M., Pugeisi, G. (1996). Correlation of trimethoprim and brodimoprim physicochemical and lipid membrane interaction properties with their accumulation in human neutrophils, Antimicrob. Agents Chemother. 40(12): 2865 - 2873. PMid:9124856 PMCid:PMC16363710.1128/AAC.40.12.2865Search in Google Scholar

2. Saha, N., Kar, S.K., (1977). Metal complexes of pyrimidine-derived ligands - I: Nickel (II) complexes of 2-hydrazino-4,6-dimethyl pyrimidine, J. Inorg. Nucl. Chem. 39, 195-200. http://dx.doi.org/10.1016/0022-1902(77)80465-X10.1016/0022-1902(77)80465-XSearch in Google Scholar

3. Shamsa, F., Amani, L. (2006). Determination of sulfamethoxazole and trimethoprim in pharmaceuticals by visible and UV spectrometry, Iran. J. Pharm. Res. 1, 31-36.Search in Google Scholar

4. Reisberg, B., Herzog, J., Weinstein, L. (1967). In vitro antibacterial activity of trimethoprim alone and in combination with sulfonamides. Antimicrob. Agents Chemother., 424-426.Search in Google Scholar

5. El-Ansary, A.L., Issa, Y.M., Selim, W. (1999). Spectrophotometric determination of trimethoprim in pure form and in pharmaceutical preparations using Bromthymol blue, Bromocresol green and Alizarin red S. Anal. Lett. 32(5): 655-969. http://dx.doi.org/10.1080/0003271990854286910.1080/00032719908542869Search in Google Scholar

6. Gemperline, P.J., Cho, J. H., Baker, B., Batchelor, B., Walker, D.S. (1997). Determination of multicomponent dissolution profiles of pharmaceutical products by in situ fiber-optic UV measurements. Anal. Chim. Acta. 345, 155-159. http://dx.doi.org/10.1016/S0003-2670(97)00095-010.1016/S0003-2670(97)00095-0Search in Google Scholar

7. Ni, Y., Q. Zj., Kokot, S. (2006). Simultaneous ultraviolet-spectrophotometric determination of sulfonamides by multivariate calibration approaches. Chemometr. Intell. Lab. 82, 241-247. http://dx.doi.org/10.1016/j.chemolab.2005.07.00610.1016/j.chemolab.2005.07.006Search in Google Scholar

8. Adekoge, O.A., Babalola, C.P., Kotila, O.A., Obuebhor, O. (2014). Simultaneous spectrophotometric determination of trimethoprim and sulphamethoxazole following charge-transfer complexation with chloranilic acid. Arabian Journal of Chemistry, in pressSearch in Google Scholar

9. Othman S. (1989). Multicomponent derivative spectroscopic analysis of sulfamethoxazole and trimethoprim. Int. J. Pharm. 63, 173-176. http://dx.doi.org/10.1016/0378-5173(90)90168-410.1016/0378-5173(90)90168-4Search in Google Scholar

10. Zimmer, Ł., Czarnecki, W. (2010). Derivative spectrophotometric method for simultaneous determination of sulfadimidine and trimethoprim. Annales Universitatis Mariae Curie-Skłodowska, Lublin - Polonia, Sectio DDD, 23(1-3): 27-36.Search in Google Scholar

11. Medina, J.R., Miranda, M., Hurtado, M., Dominguez-Ramirez, A. M., Ruiz-Segura, J.C. (2013). Simultaneous determination of trimethoprim and sulfamethoxazole in immediate-release oral dosage forms by first-order derivative spectroscopy: Application to dissolution studies. Int. J. Pharm. Pharm. Sci. 5 (Suppl.4), 505-510.Search in Google Scholar

12. Rezaee, A., Nejad, Q.B., Kebriaeezadeh, A. (2000). Simultaneous analysis of thrimethoprim and sulphamethoxazole drug combinations in dosage forms by High Performance Liquid Chromatography. Iran. Biomed. J. 4 (2&3): 75-78.Search in Google Scholar

13. Akay, C., Özkan, S.A. (2002). Simultaneous LC determination of thrimethoprim and sulfamethoxazole in pharmaceutical formulations. J. Pharm. Biomed. Anal. 30, 1207-1213. http://dx.doi.org/10.1016/S0731-7085(02)00460-010.1016/S0731-7085(02)00460-0Search in Google Scholar

14. Lemus Gallego, J.M., Perez Arroyo, J. (2002). Simultaneous determination of dexamethazone and trimethoprim by liquid chromatography. J. Pharm. Biomed. Anal. 30, 1255-1261. http://dx.doi.org/10.1016/S0731-7085(02)00468-510.1016/S0731-7085(02)00468-5Search in Google Scholar

15. Al-Sabha, T.N., Hamody, I.A. (2011). Spectrophotometric determination of trimethoprim using 2,4-dinitro-1-fluorobenzene reagent. J. Edu. & Sci. 24(2): 1-12.Search in Google Scholar

16. Chati, S., Wadookar, S.G., Kasture, A.V. (1979). Nonaqueous titrimetric method for timethoprim determination in combination. Indian J. Pahrm. Sci. 41(6): 231.Search in Google Scholar

17. Carapuca, H.M., Cabral, D.J., Rocha, L.S. (2005). Adsorptive stripping voltammetry of trimethoprim: mechanistic studies and application to the fast determination in pharmaceutical suspensions. J. Pharm. Biomed. Anal. 38(2): 364-369. http://dx.doi.org/10.1016/j.jpba.2005.01.005 PMid:1592523310.1016/j.jpba.2005.01.00515925233Search in Google Scholar

18. Chatten, L.G., Stanley-Pons, B., McLeod, P. (1982). Electrochemical determination of trimethoprim. Analyst 107, 1026-103. http://dx.doi.org/10.1039/an9820701026 PMid:714926610.1039/an98207010267149266Search in Google Scholar

19. British Pharmacopoeia 2009, Volume I & II, p. 6201-6207.Search in Google Scholar

20. ICH Harmonized tripartite guideline. Validation of analytical procedures: Text and methodology. Q2 (R1). (2005). International conference on harmonization of technical requirements for registration of pharmaceuticals for human use.Search in Google Scholar

21. Miler, J.C., Miler, J.N. (1994). Statistics for analytical chemistry. 3^rd Edition, Ellis Horwood Ltd. Chichester, West Sussex PMid:7819605Search in Google Scholar

22. Profiles of drug substances, excipients and related methodology. In: Klaus Florey (Ed.), Analytical profiles of drug substances. Volume 7. (pp. 459). 1978, San Diego, California: Academic Press, USA.Search in Google Scholar

23. Horwitz, W. (1982). Evaluation of analytical methods used for regulation of foods and drugs, Anal. Chem. 54 (1): 67A-76A. http://dx.doi.org/10.1021/ac00238a76510.1021/ac00238a765Search in Google Scholar

24. Ayad, M.R.R., Huda, M.A., Halah H. (2012). Spectrophotometric determination of trimethoprim in pure form and pharmaceutical formulations with metol and potassium hexacyanoferrate (III). Tikrit Journal of Pharmaceutical Sciences 8(2): 209-220.Search in Google Scholar