1. bookVolumen 60 (2016): Heft 3 (September 2016)
Zeitschriftendaten
License
Format
Zeitschrift
eISSN
2450-8608
Erstveröffentlichung
30 Mar 2016
Erscheinungsweise
4 Hefte pro Jahr
Sprachen
Englisch
Uneingeschränkter Zugang

Usefulness of immunohistochemical indicators for diagnosis and prognosis of poorly differentiated tumours

Online veröffentlicht: 23 Sep 2016
Volumen & Heft: Volumen 60 (2016) - Heft 3 (September 2016)
Seitenbereich: 323 - 330
Eingereicht: 11 Dec 2015
Akzeptiert: 25 Jul 2016
Zeitschriftendaten
License
Format
Zeitschrift
eISSN
2450-8608
Erstveröffentlichung
30 Mar 2016
Erscheinungsweise
4 Hefte pro Jahr
Sprachen
Englisch
Abstract

Immunohistochemical studies have become an indispensable element of establishing the correct histopathological diagnosis of poorly differentiated lesions, proving particularly suitable, and occasionally indispensable, for diagnosis of poorly differentiated neoplastic tumours. Knowledge of the mechanism of action and normal reaction of individual proteins is required in selection of the antibody pattern for a given tissue and in evaluation of the obtained results. This paper aims to promote the application of immunohistochemical techniques in routine diagnosis, especially in cases of poorly differentiated or undifferentiated tumours.

1. Aisner D.L., Maker A., Rosenberg S.A., Berman D.M.: Loss of S100 antigenicity in metastatic melanoma. Hum Pathol 2005, 36, 1016–1019.10.1016/j.humpath.2005.07.010265636516153466Search in Google Scholar

2. Azumi N., Battifora H.: The distribution of vimentin and keratin in epithelial and nonepithelial neoplasms. A comprehensive immunohistochemical study on formalin- and alcohol-fixed tumors. Am J Clin Pathol 1987, 88, 286–296.10.1093/ajcp/88.3.2862443000Search in Google Scholar

3. Barak V., Goike H., Panaretakis K.W., Einarsson R.: Clinical utility of cytokeratins as tumor markers. Clin Biochem 2004, 37, 529–540.10.1016/j.clinbiochem.2004.05.00915234234Search in Google Scholar

4. Burrai G.P., Tanca A., De Miglio M.R., Abbondio M., Pisanu S., Polinas M., Pirino S., Mohammed S.I., Uzzau S., Addis M.F., Antuofermo E.: Investigation of HER2 expression in canine mammary tumors by antibody–based, transcriptomic and mass spectrometry analysis: is the dog a suitable animal model for human breast cancer? Tumour Biol 2015, 36, 9083–9091.10.1007/s13277-015-3661-226088453Search in Google Scholar

5. Cai W., Chen K., Mohamedali K.A., Cao Q., Gambhir S.S., Rosenblum M.G., Chen X.: PET of vascular endothelial growth factor receptor expression. J Nucl Med 2006, 47, 2048–2056.Search in Google Scholar

6. Campos A.G., Campos J.A.D.B., Sanches D.S., Dagli M.L.Z., Matera J.M.: Immunohistochemical evaluation of vascular endothelial growth factor (VEGF) in splenic hemangiomas and hemangiosarcomas in dogs. Open J Vet Med 2012, 2, 191–195. doi:10.4236/ojvm.2012.24030.10.4236/ojvm.2012.24030Search in Google Scholar

7. Ermert L., Dierkes C., Ermert M.: Immunohistochemical expression of cyclooxygenase isoenzymes and downstream enzymes in human lung tumors. Clin Cancer Res 2003, 9, 1604–1610.Search in Google Scholar

8. Fetsch P.A., Abati A.: Overview of the clinical immunohistochemistry laboratory: Regulations and troubleshooting guidelines. Methods Mol Biol 1999, 115, 405–414.10.1385/1-59259-213-9:405Search in Google Scholar

9. Fuchs S.Y., Ougolkov A.V., Spiegelman V.S., Minamoto T.: Oncogenic beta-catenin signaling networks in colorectal cancer. Cell Cycle 2005, 4, 1522–1539.10.4161/cc.4.11.212916258275Search in Google Scholar

10. Galus R., Włodarski K.: Cytokeratin detection as a diagnostic tool in oncology. Pol Merk Lek 2007, 135, 209–211.Search in Google Scholar

11. Hara S., Kamei D., Sasaki Y., Tanemoto A., Nakatani Y., Murakami M.: Prostaglandin E synthases: understanding their pathophysiological roles through mouse genetic models. Biochimie 2010, 2, 651–649.10.1016/j.biochi.2010.02.00720159030Search in Google Scholar

12. Hu W.Q., Peng C.W., Li Y.: The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance–associated protein in gastric cancer. J Exp Clin Cancer Res 2009, 28, 144.10.1186/1756-9966-28-144278853619930704Search in Google Scholar

13. Illera J.V., Perez-Alenza M.D., Nieto A., Jimenez M.A., Silvan G., Dunner S., Peña L.: Steroid and receptors in canine mammary cancer. Steroids 2006, 71, 541–548.10.1016/j.steroids.2005.11.00716631217Search in Google Scholar

14. Inoue M., Wada N.: Immunohistochemical detection of p53 and p21 proteins in canine testicular tumours. Vet Rec 2000, 146, 370–372.10.1136/vr.146.13.370Search in Google Scholar

15. Janneh O., Anwar T., Jungbauer C., Kopp S., Khoo S.H., Back D.J., Chiba P.: P-glycoprotein, multidrug resistance-associated proteins and human organic anion transporting polypeptide influence the intracellular accumulation of atazanavir. Antivir Therap 2009, 14, 965–974.10.3851/IMP1399Search in Google Scholar

16. Klopfleisch R., Gruber A.D.: Differential expression of cell cycle regulators p21, p27 and p53 in metastasizing canine mammary adenocarcinomas versus normal mammary glands. Res Vet Sci 2009, 87, 91–96.10.1016/j.rvsc.2008.12.010Search in Google Scholar

17. Lawrence D.: Quality control in molecular immunohistochemistry. Histochem Cell Biol 2008, 130, 473–480.10.1007/s00418-008-0481-0Search in Google Scholar

18. Lu H., Ouyang W., Huang C.: Inflammation, a key event in cancer development. Mol Cancer Res 2006, 4, 221–233.10.1158/1541-7786.MCR-05-0261Search in Google Scholar

19. Lukas W., Jones K.A.: Cortical neurons containing calretinin are selectively resistant to calcium overload and exitotoxicity in vitro. Neuroscience 1994, 61, 307–316.10.1016/0306-4522(94)90233-XSearch in Google Scholar

20. Mariotti F., Giacomo R., Subeide M.: Immunohistochemical evaluation of ovarian hormonal receptors in canine mammary tumors. Open J Vet Med 2013, 3, 104–110.10.4236/ojvm.2013.32017Search in Google Scholar

21. Masferrer J.L., Leahy K.M., Koki A.T., Zweifel B.S., Settle S.L., Woerner M., Edwards D.A., Flickinger A.G., Moore R.J., Seibert K.: Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors. Cancer Res 2000, 60, 1306–1311.Search in Google Scholar

22. Milagres D., Rueff-Barroso C.R., Bolognese A.M., Costa A.M.A., Porto L.C.: Immunohistochemical localization of tumor necrosis factor-alpha and interleukin-6 during orthodontic movement in rats. Braz J Morphol Sci 2009, 26, 42–48.Search in Google Scholar

23. Miyoshi N., Tojo E., Oishi A., Fujiki M., Misumi K., Sakamoto H., Kameyama K., Shimizu T., Yasuda N.: Immunohistochemical detection of P-glycoprotein (PGP) and multidrug-resistance-associated protein (MRP) in canine cutaneous mast cell tumors. J Med Vet Sci 2002, 64, 531–533.10.1292/jvms.64.53112130841Search in Google Scholar

24. Muller W.A., Greene T., Liao F.: AS9. CD31 workshop panel report. In: Leucocyte typing VI. White cell differentiation antigens. Edited by Kishimoto T., Kikutani H., von dem Borne A.E.G., Goyert S.M., Mason D.Y., Miyasaka M., Moretta L., Okumura K., Shaw S., Springer T.A., Sugamura K., Zola H. Proc 6th International Workshop and Conference. Garland Publishing Inc., Kobe, Japan. New York, London 1996, pp. 362–364.Search in Google Scholar

25. Nollen E.A., Morimoto R.I.: Chaperoning signaling pathways: molecular chaperones as stress-sensing 'heat shock' proteins. J Cell Sci 2002, 115, 2809–2816.10.1242/jcs.115.14.280912082142Search in Google Scholar

26. Noseda M., Karsan A.: Notch and minichromosome maintenance (MCM) proteins: integration of two ancestral pathways in cell cycle control. Cell Cycle 2006, 5, 2704–2709.10.4161/cc.5.23.351517172856Search in Google Scholar

27. Nowińska K., Dzięgiel P.: The role of MCM proteins in cell proliferation and tumorigenesis. Postepy Hig Med Dosw 2010, 64, 627–635.Search in Google Scholar

28. Olsson M., Zhivotovsky B.: Caspases and cancer. Cell Death Differ 2011, 18, 1441–1449.10.1038/cdd.2011.30Search in Google Scholar

29. Painter J.T., Clayton N.P., Herbert R.A.: Useful Immunohistochemical markers of tumor differentiation. Toxicol Pathol 2010, 38, 131–141.10.1177/0192623309356449Search in Google Scholar

30. Paulin D., Li Z.: Desmin: a major intermediate filament protein essential for the structural integrity and function of muscle. Exp Cell Res 2004, 301, 1–7.10.1016/j.yexcr.2004.08.004Search in Google Scholar

31. Peña L.L., Nieto A.I., Pérez-Alenza D., Cuesta P., Castaño M.: Immunohistochemical detection of Ki-67 and PCNA in canine mammary tumors: relationship to clinical and pathologic variables. J Vet Diagn Invest 1998, 10, 237–246.10.1177/104063879801000303Search in Google Scholar

32. Perl A.K., Wilgenbus P., Dahl U., Semb H., Christofori G.: A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 1998, 392; 190–193.10.1038/32433Search in Google Scholar

33. Pilozzi E., Pulford K., Jones M., Müller-Hermelink H.K., Falini B., Ralfkiaer E., Pileri S., Pezzella F., De Wolf-Peeters C., Arber D., Stein H., Mason D., Gatter K.: Co-expression of CD79a (JBC117) and CD3 by lymphoblastic lymphoma. J Pathol 1998, 186, 140–143.10.1002/(SICI)1096-9896(1998100)186:2<140::AID-PATH149>3.0.CO;2-YSearch in Google Scholar

34. Pusztaszeri M.P., Seelentag W., Bosman F.T.: Immunohistochemical expression of endothelial markers CD31, CD34, von Willebrand Factor, and Fli-1 in normal human tissues. J Histochem Cytochem 2006, 54, 385–395.10.1369/jhc.4A6514.2005Search in Google Scholar

35. Queiroga F.L., Perez-Alenza M.D., González-Gil A., Silván G., Peña L., Illera J.C.: Quantification of epidermal growth factor receptor (EGFR) in canine mammary tumours by ELISA: clinical and prognostic implications. Vet Comp Oncol 2015, doi: 10.1111/vco.12174.10.1111/vco.12174Search in Google Scholar

36. Radi Z.A., Miller D.L.: Immunohistochemical expression of calretinin in canine testicular tumours and normal canine testicular tissue. Res Vet Sci 2005, 79, 125–129.10.1016/j.rvsc.2004.11.016Search in Google Scholar

37. Restucci B., Maiolino P., Martano M., Esposito G., De Filippis D., Borzacchiello G., Lo Muzio L.: Expression of β-Catenin, E-cadherin and APC in canine mammary tumors. Anticancer Res 2007, 27, 3083–3090.Search in Google Scholar

38. Rickers R.R., Malinisk R.M.: Intralaboratory quality assurance of immunohistochemical procedures: recommended practices for daily application. Arch Pathol Lab Med 1989, 113, 673–679.Search in Google Scholar

39. Taylor C.R., Shi S.R., Barr N.J.: Techniques of Immunohistochemistry: Principles, Pitfalls, and Standardization. In: Diagnostic Immunohistochemistry, edited by D. Dabbs, Saunders Elsevier, Pittsburgh, USA, 2006, pp. 1–41.Search in Google Scholar

40. Toniti W., Buranasinsup S., Kongcharoen A., Charoonrut P., Puchadapirom P., Kasorndorkbua C.: Immunohistochemical determination of estrogen and progesterone receptors in canine mammary tumors. Asian Pac J Cancer Prev 2009, 10, 907–911.Search in Google Scholar

41. Vaseva A.V., Moll U.M.: The mitochondrial p53 pathway. Biochim Biophys Acta 2009, 1787, 414–420.10.1016/j.bbabio.2008.10.005Search in Google Scholar

42. Webster J.D., Yuzbasiyan-Gurkan V., Kaneene J.B., Miller R.A., Resau J.H., Kiupel M.: The role of c-KIT in tumorigenesis: evaluation in canine cutaneous mast cell tumors. Neoplasia 2006, 8, 104–111.10.1593/neo.05622157851616611403Search in Google Scholar

43. Weng Y.R., Cui Y., Fang J.Y.: Biological functions of cytokeratin 18 in cancer. Mol Cancer Res 2012, 10, 485–493.10.1158/1541-7786.MCR-11-022222452884Search in Google Scholar

44. Werner M., Chott A., Fabiano A., Battifora H.: Effect of formalin tissue fixation and processing on immunohistochemistry. Am J Surg Pathol 2000, 24, 1016–1019.10.1097/00000478-200007000-0001410895825Search in Google Scholar

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