<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Peripheral artery diseases include all arterial diseases with the exception of coronary and aortic involvement, more specifically diseases of the extracranial carotids, upper limb arteries, mesenteric and renal vessels, and last but not least, lower limb arteries. Mononuclear stem cells, harvested from various sites (bone marrow, peripheral blood, mesenchymal cells, adipose-derived stem cells) have been studied as a treatment option for alleviating symptoms in peripheral artery disease, as potential stimulators for therapeutic angiogenesis, thus improving vascularization of the ischemic tissue. The aim of this manuscript was to review current medical literature on a novel treatment method — cell therapy, in patients with various peripheral vascular diseases, including carotid, renal, mesenteric artery disease, thromboangiitis obliterans, as well as upper and lower limb artery disease.</p></abstract>

Peripheral artery diseases include all arterial diseases with the exception of coronary and aortic involvement, more specifically diseases of the extracranial carotids, upper limb arteries, mesenteric and renal vessels, and last but not least, lower limb arteries. Mononuclear stem cells, harvested from various sites (bone marrow, peripheral blood, mesenchymal cells, adipose-derived stem cells) have been studied as a treatment option for alleviating symptoms in peripheral artery disease, as potential stimulators for therapeutic angiogenesis, thus improving vascularization of the ischemic tissue. The aim of this manuscript was to review current medical literature on a novel treatment method — cell therapy, in patients with various peripheral vascular diseases, including carotid, renal, mesenteric artery disease, thromboangiitis obliterans, as well as upper and lower limb artery disease.

Stem Cell Therapies in Peripheral Vascular Diseases — Current Status

Center of Advanced Research in Multimodality Cardiac Imaging, Cardio Med Medical Center

Clinic of Hematology and Bone Marrow Transplantation Unit

Journal of Interdisciplinary Medicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Stem Cell Therapies in Peripheral Vascular Diseases \u2014 Current Status"}

Peripheral artery diseases include all arterial diseases with the exception of coronary and aortic involvement, more specifically diseases of the extracranial...

Stem Cell Therapies in Peripheral Vascular Diseases — Current Status

Online veröffentlicht: 12. März 2018

Seitenbereich: 12 - 19

Eingereicht: 01. Okt. 2017

Akzeptiert: 30. Okt. 2017

DOI: https://doi.org/10.1515/jim-2017-0093

Schlüsselwörter
stem cells, peripheral vascular diseases, endothelial precursor cells, therapeutic angiogenesis

© 2017 Diana Opincariu et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Stem Cell Therapies in Peripheral Vascular Diseases — Current Status

Online veröffentlicht: 12. März 2018

Seitenbereich: 12 - 19

Eingereicht: 01. Okt. 2017

Akzeptiert: 30. Okt. 2017

DOI: https://doi.org/10.1515/jim-2017-0093

Schlüsselwörterstem cells, peripheral vascular diseases, endothelial precursor cells, therapeutic angiogenesis

© 2017 Diana Opincariu et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Schlüsselwörter
stem cells, peripheral vascular diseases, endothelial precursor cells, therapeutic angiogenesis