<abstract xmlns="http://www.w3.org/1999/xhtml">

<p> The aim of this study was to assess the effect of thymus factor X (TFX-Jelfa) treatment in hypoestrogenic female rats for the purpose of decreasing skin impairments. Ovariectomised rats were used as a model. The histopathological analysis of the skin after TFX-Jelfa treatment demonstrated that the epidermis was thicker and more desquamated, without deep wrinkles or hypersecretion in comparison to the skin of animals only castrated and not treated with TFX-Jelfa. Collagen and elastic fibres were arranged more uniformly in the dermis and there were numerous fibroblasts, hair follicles, and small vessels. Ultrastructural analysis showed keratinocytes without degenerative changes and the proliferation of lymphatic and dendritic cells in the skin. The results indicate that thymus extracts can have beneficial effects on skin aging, which is often accompanied by hormonal perturbances.</p>
</abstract>

The aim of this study was to assess the effect of thymus factor X (TFX-Jelfa) treatment in hypoestrogenic female rats for the purpose of decreasing skin impairments. Ovariectomised rats were used as a model. The histopathological analysis of the skin after TFX-Jelfa treatment demonstrated that the epidermis was thicker and more desquamated, without deep wrinkles or hypersecretion in comparison to the skin of animals only castrated and not treated with TFX-Jelfa. Collagen and elastic fibres were arranged more uniformly in the dermis and there were numerous fibroblasts, hair follicles, and small vessels. Ultrastructural analysis showed keratinocytes without degenerative changes and the proliferation of lymphatic and dendritic cells in the skin. The results indicate that thymus extracts can have beneficial effects on skin aging, which is often accompanied by hormonal perturbances.

Curative effect of TFX-Jelfa supplementation on the skin of ovariectomised rats – morphological study

Department of Internal Diseases of Farm Animals and Horses, Faculty of Veterinary Medicine

Journal of Veterinary Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The aim of this study was to assess the effect of thymus factor X (TFX-Jelfa) treatment in hypoestrogenic female rats for the purpose of decreasing skin...

Curative effect of TFX-Jelfa supplementation on the skin of ovariectomised rats – morphological study

Online veröffentlicht: 03. Juli 2015

Seitenbereich: 311 - 315

Eingereicht: 13. Okt. 2014

Akzeptiert: 08. Juni 2015

DOI: https://doi.org/10.1515/bvip-2015-0045

© 2015 National Veterinary Research Institute in Pulawy

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.