<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Pure mucinous carcinoma is a rare special type of breast carcinoma with a 2% incidence and it is usualy asociated with a good prognosis. It must distingished from the mixed subtype of mucinos breast carcinoma, which has an invasive non-mucinous component in more than 10% of the tumor and change the favourable outcome of the first subtype. In this report we present a case of a premenopausal woman with a lump in right breast wich histopathologically proved to be a pure mucinous carcinoma associated with high grade ductal carcinoma in situ. Immunohistochemical and ancillary studies demonstrate a great heterogeneity of the neoplastic cells, with different molecular profile for each component of the tumor. The presence of ductal carcinoma in situ with a different imunophenotype from pure mucinous carcinoma rise the ipothesis of a different tumor cell biology which may change clincal evolution.</p></abstract>

Pure mucinous carcinoma is a rare special type of breast carcinoma with a 2% incidence and it is usualy asociated with a good prognosis. It must distingished from the mixed subtype of mucinos breast carcinoma, which has an invasive non-mucinous component in more than 10% of the tumor and change the favourable outcome of the first subtype. In this report we present a case of a premenopausal woman with a lump in right breast wich histopathologically proved to be a pure mucinous carcinoma associated with high grade ductal carcinoma in situ. Immunohistochemical and ancillary studies demonstrate a great heterogeneity of the neoplastic cells, with different molecular profile for each component of the tumor. The presence of ductal carcinoma in situ with a different imunophenotype from pure mucinous carcinoma rise the ipothesis of a different tumor cell biology which may change clincal evolution.

Morphopathological and immunohistochemical features of a pure mucinous breast carcinoma – Case report

Associated member of Academy of Romanian Scientists

Department of Pathology, Faculty of Medicine, “Ovidius” University, Constanta

Clinical Service of Pathology, Emergency County Hospital “Sf. Apostol Andrei” Constanta

ARS Medica Tomitana

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Pure mucinous carcinoma is a rare special type of breast carcinoma with a 2% incidence and it is usualy asociated with a good prognosis. It must distingished...

Morphopathological and immunohistochemical features of a pure mucinous breast carcinoma – Case report

Online veröffentlicht: 18. Jan. 2017

Seitenbereich: 174 - 180

DOI: https://doi.org/10.1515/arsm-2016-0029

Schlüsselwörter
Pure mucinous breast carcinoma, ductal carcinoma in situ, immunohistochemistry, CISH

© 2016 Aschie Mariana et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Morphopathological and immunohistochemical features of a pure mucinous breast carcinoma – Case report

Online veröffentlicht: 18. Jan. 2017

Seitenbereich: 174 - 180

DOI: https://doi.org/10.1515/arsm-2016-0029

SchlüsselwörterPure mucinous breast carcinoma, ductal carcinoma in situ, immunohistochemistry, CISH

© 2016 Aschie Mariana et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Schlüsselwörter
Pure mucinous breast carcinoma, ductal carcinoma in situ, immunohistochemistry, CISH