<abstract xmlns="http://www.w3.org/1999/xhtml"><p> We assume that the CRISPR Cas9 theory must be delimited by applicability, because the consequences of long term DNA manipulation remain unknown. Moreover, the irreversibility of this procedure should instigate researchers to reserved opinions.</p><p>Usefulness as well as benefits of CRISPR Cas9 made it one of the most popular and used genome editing technique. But with its huge potential, ethical and safety concerns emerge. Therefore, before continuing research in this direction we should have a well organized system that is able to make that differentiation between research and reproduction. However we truly believe in the future of genetic engineering and with the CRISPR-Cas9 system we expect that the opportunity of treating now so called incurable diseases arises. Time is all we need.</p></abstract>

We assume that the CRISPR Cas9 theory must be delimited by applicability, because the consequences of long term DNA manipulation remain unknown. Moreover, the irreversibility of this procedure should instigate researchers to reserved opinions.Usefulness as well as benefits of CRISPR Cas9 made it one of the most popular and used genome editing technique. But with its huge potential, ethical and safety concerns emerge. Therefore, before continuing research in this direction we should have a well organized system that is able to make that differentiation between research and reproduction. However we truly believe in the future of genetic engineering and with the CRISPR-Cas9 system we expect that the opportunity of treating now so called incurable diseases arises. Time is all we need.

Review. Development, Applications, Benefits, Challenges and Limitations of the New Genome Engineering Technique. An Update Study

University of Medicine and Pharmacy Tirgu Mures,

University of Medicine and Pharmacy Tirgu Mures, Romania

Center for Advanced Medical and Pharmaceutical Research, University of Medicine and Pharmacy Tirgu Mureș,

Acta Marisiensis - Seria Medica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

We assume that the CRISPR Cas9 theory must be delimited by applicability, because the consequences of long term DNA manipulation remain unknown. Moreover, the...

Review. Development, Applications, Benefits, Challenges and Limitations of the New Genome Engineering Technique. An Update Study

Online veröffentlicht: 20. Apr. 2017

Seitenbereich: 4 - 9

Eingereicht: 07. Nov. 2016

Akzeptiert: 03. Feb. 2017

DOI: https://doi.org/10.1515/amma-2017-0007

Schlüsselwörter
CRISPR-Cas9, Cpf1, Class 2 CRISPR effector, RNA guided

© by Florin Tripon

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Review. Development, Applications, Benefits, Challenges and Limitations of the New Genome Engineering Technique. An Update Study

Online veröffentlicht: 20. Apr. 2017

Seitenbereich: 4 - 9

Eingereicht: 07. Nov. 2016

Akzeptiert: 03. Feb. 2017

DOI: https://doi.org/10.1515/amma-2017-0007

SchlüsselwörterCRISPR-Cas9, Cpf1, Class 2 CRISPR effector, RNA guided

© by Florin Tripon

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Schlüsselwörter
CRISPR-Cas9, Cpf1, Class 2 CRISPR effector, RNA guided