<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Objective</bold>: The aim of the study was to describe clinical and laboratory characteristics in HIV-infected patients with Kaposi sarcoma (KS).<bold>Methods</bold>: We retrospectively studied data on HIV-infected patients hospitalized in one tertiary care hospital in Bucharest, Romania, in whom Kaposi Sarcoma was diagnosed, between January 2008 and November 2013.<bold>Results</bold>: We identified 27 HIV-infected patients diagnosed with KS within 6 years. They had a median age of 42 years old and a median CD4 cell count of 101 cells per mm3 at the time of KS diagnosis. All patients received antiretroviral therapy (ART), with 18 patients (66%) already on ART at the time of KS diagnosis. Most patients (59%) were classified as ACTG poor-risk and 56% as Mitsuyasu stage I. The overall prognosis was poor, with 41% mortality, in a median time span of 6 months, significantly correlated with gastrointestinal involvement (p=0.019), poor-risk KS in ACTG classification (p&lt;0.001) and stage IV Mitsuyasu (p=0.006).<bold>Conclusion</bold>: KS remains an important cause of morbidity and mortality in patients with HIV infection, especially in late presenters.</abstract>

Objective: The aim of the study was to describe clinical and laboratory characteristics in HIV-infected patients with Kaposi sarcoma (KS).Methods: We retrospectively studied data on HIV-infected patients hospitalized in one tertiary care hospital in Bucharest, Romania, in whom Kaposi Sarcoma was diagnosed, between January 2008 and November 2013.Results: We identified 27 HIV-infected patients diagnosed with KS within 6 years. They had a median age of 42 years old and a median CD4 cell count of 101 cells per mm3 at the time of KS diagnosis. All patients received antiretroviral therapy (ART), with 18 patients (66%) already on ART at the time of KS diagnosis. Most patients (59%) were classified as ACTG poor-risk and 56% as Mitsuyasu stage I. The overall prognosis was poor, with 41% mortality, in a median time span of 6 months, significantly correlated with gastrointestinal involvement (p=0.019), poor-risk KS in ACTG classification (p<0.001) and stage IV Mitsuyasu (p=0.006).Conclusion: KS remains an important cause of morbidity and mortality in patients with HIV infection, especially in late presenters.

Kaposi Sarcoma in HIV Infected Patients

National Institute of Infectious Diseases “Prof. Dr. Matei Balș”, Bucharest, Romania; “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania

Acta Marisiensis - Seria Medica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Kaposi Sarcoma in HIV Infected Patients"}

Objective: The aim of the study was to describe clinical and laboratory characteristics in HIV-infected patients with Kaposi sarcoma (KS).Methods: We...

Kaposi Sarcoma in HIV Infected Patients

Online veröffentlicht: 20. Mai 2016

Seitenbereich: 285 - 288

Eingereicht: 19. Feb. 2016

Akzeptiert: 29. März 2016

DOI: https://doi.org/10.1515/amma-2016-0019

Schlüsselwörter
Kaposi disease, HIV, late presenters

© 2016 Jipa Raluca et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Kaposi Sarcoma in HIV Infected Patients

Online veröffentlicht: 20. Mai 2016

Seitenbereich: 285 - 288

Eingereicht: 19. Feb. 2016

Akzeptiert: 29. März 2016

DOI: https://doi.org/10.1515/amma-2016-0019

SchlüsselwörterKaposi disease, HIV, late presenters

© 2016 Jipa Raluca et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Schlüsselwörter
Kaposi disease, HIV, late presenters