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Figure 1
Sperm quality parameters in rats in the group with streptozotocin-induced diabetes mellitus (gray bars) compared with those in vehicle treated rats in the control group (unfilled bars). (A) Percentage of sperm motility. (B) Percentage of normal sperm morphology. (C) Sperm concentration. Bars represent mean percentages or concentrations, and error bars represent standard error of the mean; t test ***P< 0.001
Figure 2
The diameter of seminiferous tubules in rats with streptozotocin-induced diabetes mellitus (gray bars) compared with that in vehicle treated rats in the control group (unfilled bars). Bars represent mean diameters, and error bars represent standard error of the mean; t test *P< 0.05
Figure 3
Seminiferous tubule morphology. (A) Normal morphology in vehicle-treated rats. Changes in morphology in rats with streptozotocin- induced diabetes mellitus (B) separation of the germinal epithelium (arrows), (C) vacuolization (arrows), (D) luminal sloughing of germ cells (arrows), (E) irregular tube (dashed circle), and (F) atrophy (dashed circle). Scale bars represent 50 μm (magnification 200×)
Figure 4
Morphological changes of seminiferous tubules in rats with streptozotocin-induced diabetes mellitus (gray bars) compared with those in vehicle-treated rats in the control group (unfilled bars). Bars represent mean percentages of abnormalities, and error bars represent standard error of the mean. t test #P< 0.1; *P< 0.05; **P< 0.01; ***P< 0.001
Figure 5
Proportion of seminiferous tubules at various stages of development in rats with streptozotocin-induced diabetes mellitus (gray bars) compared with that in vehicle-treated rats in the control group (unfilled bars). Bars represent mean percentages at the various stages, and error bars represent standard error of the mean. t test ***P< 0.001
Body weight, testicular weight, and the testicular weight percentage of body weight in rats in rats in the group with streptozotocin-induced diabetes mellitus and in the vehicle treated control group