1. bookVolume 66 (2017): Issue 1 (March 2017)
Journal Details
License
Format
Journal
eISSN
2544-4646
First Published
04 Mar 1952
Publication timeframe
4 times per year
Languages
English
access type Open Access

From Latent Tuberculosis Infection to Tuberculosis. News in Diagnostics (QuantiFERON-Plus)

Published Online: 30 Mar 2017
Volume & Issue: Volume 66 (2017) - Issue 1 (March 2017)
Page range: 5 - 8
Received: 19 Aug 2016
Accepted: 27 Jan 2017
Journal Details
License
Format
Journal
eISSN
2544-4646
First Published
04 Mar 1952
Publication timeframe
4 times per year
Languages
English
Abstract

It is estimated that one third of the world’s population have latent tuberculosis infection and that this is a significant reservoir for future tuberculosis cases. Most cases occur within two years following initial infection. The identification of individuals with latent tuberculosis infection is difficult due to the lack of an ideal diagnostic assay and incomplete understanding of latent infection. Currently, there are three tests: the oldest tuberculin skin test, T-SPOT.TB and the latest QuantiFERON-Plus for the detection of Mycobacterium tuberculosis infection. The interpretation of the test results must be used in the conjunction with a patient’s epidemiological history, risk assessment, current clinical status, radiography and microbiological methods to ensure accurate diagnosis.

Key words

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