<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Penicillin G oversecretion by <italic>Penicillium chrysogenum</italic> PQ-96 is associated with a strictly adjusted cellular organization of the mature and senescent mycelial cells. Abundant vacuolar phagy and extended cellular vacuolization combined with vacuolar budding resulting in the formation of vacuolar vesicles that fuse with the cell membrane are the most important characteristic features of those cells. We suggest as follows: if the peroxisomes are integrated into vacuoles, the penicillin G formed in peroxisomes might be transferred to vacuoles and later secreted out of the cells by an exocytosis process. The peroxisomal cells of the mycelium are privileged in penicillin G secretion.</p>
</abstract>

Penicillin G oversecretion by Penicillium chrysogenum PQ-96 is associated with a strictly adjusted cellular organization of the mature and senescent mycelial cells. Abundant vacuolar phagy and extended cellular vacuolization combined with vacuolar budding resulting in the formation of vacuolar vesicles that fuse with the cell membrane are the most important characteristic features of those cells. We suggest as follows: if the peroxisomes are integrated into vacuoles, the penicillin G formed in peroxisomes might be transferred to vacuoles and later secreted out of the cells by an exocytosis process. The peroxisomal cells of the mycelium are privileged in penicillin G secretion.

Pexophagy in Penicillin G Secretion by <italic>Penicillium chrysogenum</italic> PQ-96

Polish Journal of Microbiology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Pexophagy in Penicillin G Secretion by  PQ-96

Penicillin G oversecretion by Penicillium chrysogenum PQ-96 is associated with a strictly adjusted cellular organization of the mature and senescent mycelial...

Pexophagy in Penicillin G Secretion by Penicillium chrysogenum PQ-96

Published Online: Aug 26, 2016

Page range: 365 - 368

Received: Nov 27, 2015

Accepted: Feb 13, 2016

DOI: https://doi.org/10.5604/17331331.1215616

Keywords
penicillin G, secretion

© 2016 WIESŁAW KURZĄTKOWSKI et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Pexophagy in Penicillin G Secretion by Penicillium chrysogenum PQ-96

Published Online: Aug 26, 2016

Page range: 365 - 368

Received: Nov 27, 2015

Accepted: Feb 13, 2016

DOI: https://doi.org/10.5604/17331331.1215616

Keywordspenicillin G, secretion

© 2016 WIESŁAW KURZĄTKOWSKI et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
penicillin G, secretion