Prevalence of impaired lower airway function in Thai patients with allergic rhinitis
, , , , and | Jan 31, 2017
About this article
Article Category: Brief communication (Original)
Published Online: Jan 31, 2017
Page range: 67 - 74
DOI: https://doi.org/10.5372/1905-7415.1001.467
Keywords
© 2016 Pongsakorn Tantilipikorn, Jitraporn Juntabenjapat, Torpong Thongngarm, Paraya Assanasen, Chaweewan Bunnag, Bandit Thinkhamrop, published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Figure 1
Prevalence of abnormal pulmonary function (Force expiratory volume in 1 s <80%), duration of allergy, severity of allergic symptoms, and sensitization to allergens
| Number | Prevalence (%) | |
|---|---|---|
| Overall prevalence | 153 | 23 (15) |
| Duration of allergy | ||
| ≤ 5 years | 62 | 10 (16) |
| 5-10 years | 52 | 7 (14) |
| ≥ 10 years | 39 | 6 (15) |
| Severity of allergic symptoms | ||
| Mild intermittent | 38 | 4 (11) |
| Moderate/severe intermittent | 37 | 5 (14) |
| Mild persistent | 19 | 2 (11) |
| Moderate/severe persistent | 59 | 12 (20) |
| Sensitization to indoor allergens | 25 | 1 (4) |
| Sensitization to outdoor allergens | 16 | 1 (6) |
| Sensitization to both indoor and outdoor allergens | 112 | 21 (19) |
Clinical characteristics and their relation to percent changes of FEV1
| Characteristics | Total | Subject with percent change FEV1≥ 12% | OR | 95%CI | |
|---|---|---|---|---|---|
| Duration of allergy (y) | |||||
| ≤ 5 | 62 | 0 (0%) | - | - | |
| 5-10 | 52 | 3 (5.8%) | - | - | 0.06 |
| ≥ 10 | 39 | 1 (2.6%) | - | - | 0.21 |
| Severity of allergic symptoms | |||||
| Mild intermittent | 38 | 1 (2.63%) | 1 | - | |
| Moderate/severe intermittent | 37 | 1 (2.7%) | 1.03 | 0.07-15.82 | 0.99 |
| Mild persistent | 19 | 0 (0%) | 0 | - | 0.48 |
| Moderate/severe persistent | 59 | 2 (3.39%) | 1.28 | 0.12-13.71 | 0.83 |
| Sensitization to indoor allergens | 25 | 2 (8%) | 5.12 | 0.75-34.66 | 0.06 |
| Sensitization to outdoor allergens | 16 | 0 (0%) | 0 | 0 | 0.48 |
| Sensitization to indoor and outdoor allergens | 112 | 2 (1.79%) | 0.36 | 0.05-2.51 | 0.28 |
Clinical characteristics and their relation to FEV1
| Characteristics | Total | Subject with FEV1 < 80% | OR | 95%CI | |
|---|---|---|---|---|---|
| Duration of allergy (y) | |||||
| ≤ 5 | 62 | 10 (16%) | 1 | - | |
| 5-10 | 52 | 7 (14%) | 0.83 | 0.34-2.04 | 0.691 |
| ≥ 10 | 39 | 6 (15%) | 0.95 | 0.38-2.42 | 0.921 |
| Severity of allergic symptoms | - | ||||
| Mild intermittent | 38 | 4 (11%) | 1 | - | |
| Moderate/severe intermittent | 37 | 5 (14%) | 1.28 | 0.37-4.41 | 0.691 |
| Mild persistent | 19 | 2 (11%) | 1 | 0.20-4.98 | 1.000 |
| Moderate/severe persistent | 59 | 12 (20%) | 1.93 | 0.67-5.55 | 0.203 |
| Sensitization to indoor allergens | 59 | 1 (4%) | 0.23 | 0.08-1.65 | 0.09 |
| Sensitization to outdoor allergens | 16 | 1 (6%) | 0.39 | 0.06-2.69 | 0.29 |
| Sensitization to indoor and outdoor allergens | 112 | 21 (19%) | 7.79 | 1.08-55.91 |
Clinical characteristics and their relation to FEF25–75
| Characteristics | Total | Participant with FEF2–75<80% | OR | 95%CI | |
|---|---|---|---|---|---|
| Duration of allergy (y) | |||||
| ≤ 5 | 62 | 10 (16%) | 1 | - | |
| 5-10 | 52 | 14 (27%) | 1.67 | 0.81-3.04 | 0.16 |
| ≥ 10 | 39 | 13 (33%) | 2.07 | 1.01-4.25 | |
| Severity of allergic symptoms | |||||
| Mild intermittent | 38 | 10 (26%) | 1 | - | |
| Moderate/severe intermittent | 37 | 9 (24%) | 0.92 | 0.42-2.01 | 0.04 |
| Mild persistent | 19 | 4 (21%) | 0.80 | 0.28-2.21 | 0.66 |
| Moderate/severe persistent | 59 | 14 (24%) | 0.90 | 0.44-1.81 | 0.77 |
| Sensitization to indoor allergens | 25 | 8 (32%) | 1.41 | 0.73-2.71 | 0.31 |
| Sensitization to outdoor allergens | 16 | 6 (38%) | 1.66 | 0.82-3.35 | 0.19 |
| Sensitization to both indoor and outdoor allergens | 112 | 23 (21%) | 0.60 | 0.34-1.05 | 0.08 |
Prevalence of abnormal pulmonary function test results
| Number (percent) | |
|---|---|
| Abnormal FEV1 | 23 (15%) |
| Abnormal % change of FEV1 | 4 (3%) |
| Abnormal FEF25–75 | 37 (24%) |
Patient characteristics
| Characteristics | Number (percent) |
|---|---|
| Age (years) | |
| Mean ± standard deviation | 34.4 ±10.5 (range 20-59) |
| Sex | |
| Male/Female | 46 (30%)/107 (70%) |
| Duration of symptoms | |
| ≤ 5 years | 62 (41%) |
| 5-10 years | 52 (34%) |
| ≥ 10 years | 39 (26%) |
| Severity of allergic rhinitis | |
| Mild intermittent | 38 (25%) |
| Moderate/severe intermittent | 37 (24%) |
| Mild persistent | 19 (12%) |
| Moderate/severe persistent | 59 (39%) |
| Allergic to indoor allergens | 25 (16%) |
| Allergic to outdoors allergens | 16 (11%) |
| Allergic to both indoor and outdoor allergens | 112 (73%) |