Equation scores | Mean ± SD | Number (%) | ||
---|---|---|---|---|
Low | Intermediate | High | ||
Without attributable risk of psoriasis | 5.8 ± 6.9 | 109 (75) | 30 (21) | 6 (4) |
With attributable risk of psoriasis | 7.9 ± 7.3 | 97 (67) | 38 (26) | 10 (7) |
5.5 ± 5.1 | 126 (87) | 17 (12) | 2 (1) |
Variables | RAMA-EGAT score | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|---|
<10% risk (n = 126) | ≥10% risk (n = 19) | OR (95% CI) | OR (95% CI) | ||||
Duration of disease in years, mean ± SD | 12.5 ± 9.0 | 18.1 ± 9 . 7 | 0.02 | 1.06 (1.01,1.12) | 0.02 | 1.08 (1.01, 1.14) | |
Severity Only 142 and 134 patients were available for the data regarding severity and obesity, respectively, OR = odds ratio, 95% CI = 95% confidence interval, SD = standard deviation | |||||||
PASI <10 | 76 (62) | 16 (84) | 0.07 | 1 | 0.12 | 0.33 (0.08, 1.34) | |
PASI ≥ 10 | 47 (38) | 3 (16) | 0.30 (0.08,1.10) | ||||
Psoriatic arthritis, n (%) | |||||||
No | 108 (86) | 14 (74) | 0.19 | 1 | 0.48 | 1.64 (0.42, 6.39) | |
Yes | 18 (14) | 5 (26) | 2.14 (0.69,6.68) | ||||
Treatment, n (%) | |||||||
Topical | 42 (33) | 10 (53) | 0.11 | 1 | 0.02 | ||
Systemic | 84 (67) | 9 (47) | 2.22 (0.84,5.88) | 3.95 (1.23, 12.68) | |||
Obesity Only 142 and 134 patients were available for the data regarding severity and obesity, respectively, OR = odds ratio, 95% CI = 95% confidence interval, SD = standard deviation | |||||||
No | 50 (43) | 5 (28) | 0.23 | 1 | 0.19 | 2.22 (0.67, 7.34) | |
Yes | 66 (57) | 13 (72) | 1.97 (0.66,5.89) |
Demographic data | Mean ± SD or n (%) |
---|---|
Age (years) | 48.1 ± 14.1 |
Age of onset (years) | 34.9 ± 14.0 |
Duration of psoriasis (years) | 13.2 ± 9.2 |
Sex | |
Male | 72 (50) |
Female | 73 (50) |
Type of psoriasis by age of onset | |
Type I (≤40 years) | 101 (70) |
Type II (>40 years) | 44 (30) |
Clinical type of psoriasis | |
Plaque-type psoriasis | 133 (92) |
Guttate psoriasis | 5 (3) |
Psoriasis erythroderma | 4 (3) |
Pustular psoriasis | 3 (2) |
Number of patients who had psoriatic arthritis | 23 (16) |
Disease severity (n = 142) | |
PASI <10 | 92 (65) |
PASI ≥10 | 50 (35) |
Family history of psoriasis | 26 (18) |
Treatment of psoriasis | |
Topical therapy alone | 52 (36) |
Systemic therapy | 93 (64) |
Underlying diseases | |
Obesity(BMI ≥25 kg/m2) | 79 (59) |
Hypertension | 58 (40) |
Dyslipidemia | 27 (19) |
Diabetes mellitus | 23 (16) |
Nonalcoholic fatty liver | 7 (5) |
HIV infection | 4 (3) |
BMI (kg/m2) | 26.6 ± 6.4 |
Waist circumference >90 cm | 82 (43) |
Fasting blood sugar level (mg/dL) | 105.8 ± 23.8 |
Total cholesterol level (mg/dL) | 198.3 ± 37.3 |
HDL cholesterol level (mg/dL) | 51.5 ± 14.0 |
Current smoking | 23 (16) |
Variables | FRS | Univariate analysis | Multivariate analysis | |||
---|---|---|---|---|---|---|
<10% risk (n = 109) | ≥10% risk (n = 36) | OR (95% CI) | OR (95% CI) | |||
Duration of disease in years, mean ± SD | 11.9 ± 8.3 | 17.1 ± 10.7 | <0.001 | 1.14 (1.02, 1.11) | 0.001 | 1.09 (1.04,1.14) |
Severity Only 142 and 134 patients were available for the data regarding severity and obesity, respectively, OR = odds ratio 95% CI = 95% confidence interval, SD = standard deviation, FRS = Framingham Risk Score, PASI = Psoriasis Area and Severity Index | ||||||
PASI <10 | 64 (59) | 28 (78) | 0.06 | 1 | ||
PASI ≥10 | 42 (39) | 8 (22) | 0.44 (0.18, 1.05) | |||
Psoriatic arthritis, n (%) | ||||||
No | 94 (86) | 28 (78) | 0.23 | 1 | ||
Yes | 15 (14) | 8 (22) | 1.79 (0.69, 4.66) | |||
Treatment, n (%) | 0.005 | 0.002 | ||||
Topical | 32 (29) | 20 (56) | 31.03 (1.39, 6.54) | 4.63 (1.78, 12.05) | ||
Systemic | 77 (71) | 16 (44) | 1 | |||
Obesity Only 142 and 134 patients were available for the data regarding severity and obesity, respectively, OR = odds ratio 95% CI = 95% confidence interval, SD = standard deviation, FRS = Framingham Risk Score, PASI = Psoriasis Area and Severity Index | ||||||
No | 55 (51) | 24 (67) | 0.07 | 1 | 0.04 | |
Yes | 46 (42) | 9 (25) | 2.23 (0.94, 5.27) | 2.88 (1.08, 7.68) | ||
Diabetes mellitus, n (%) | ||||||
No | 95 (87) | 27 (75) | 0.09 | 1 | 0.21 | 1.99 (0.68, 5.75) |
Yes | 14 (13) | 9 (25) | 2.26 (0.88, 5.79) |