<abstract xmlns="http://www.w3.org/1999/xhtml"> Background: Intraocular pressure (IOP) is the most important risk factor in glaucoma. Before each measurement, anesthetic eye drop must be applied. The effect of these eye drops may affect the central corneal thickness (CCT) and the IOP. Objective: We investigated the effect of 0.5% tetracaine hydrochloride on central CCT and IOP in glaucoma patients. Methods: Glaucoma subjects aged ≥18 years, with spherical refractive error &lt;±6 diopters(D) and astigmatism ≤3D were included. All underwent CCT and IOP measurement using Orbscan II and air-puff tonometer at baseline, and 1, 3, 5, 7, 9, 11, 13, and 15 minutes after application of 0.5% tetracaine hydrochloride. Results: There were 19 and 24 eyes eligible for CCT and IOP measurements. The mean±SD ages were 62.7±8.2 and 62.9±8.3 years. The mean±SD CCT at baseline was 527.8±32.2 μm. The mean±SD IOP at baseline was 13.2±5.6 mmHg. Although CCT did not change from baseline (p = 0.071), IOP significantly decreased from baseline at three, seven, and 11 minutes (p = 0.003, &lt;0.001, and 0.002). Conclusions: CCT and IOP change trends were different. Although IOP decreased from baseline, CCT was unchanged.</abstract>

Background: Intraocular pressure (IOP) is the most important risk factor in glaucoma. Before each measurement, anesthetic eye drop must be applied. The effect of these eye drops may affect the central corneal thickness (CCT) and the IOP. Objective: We investigated the effect of 0.5% tetracaine hydrochloride on central CCT and IOP in glaucoma patients. Methods: Glaucoma subjects aged ≥18 years, with spherical refractive error <±6 diopters(D) and astigmatism ≤3D were included. All underwent CCT and IOP measurement using Orbscan II and air-puff tonometer at baseline, and 1, 3, 5, 7, 9, 11, 13, and 15 minutes after application of 0.5% tetracaine hydrochloride. Results: There were 19 and 24 eyes eligible for CCT and IOP measurements. The mean±SD ages were 62.7±8.2 and 62.9±8.3 years. The mean±SD CCT at baseline was 527.8±32.2 μm. The mean±SD IOP at baseline was 13.2±5.6 mmHg. Although CCT did not change from baseline (p = 0.071), IOP significantly decreased from baseline at three, seven, and 11 minutes (p = 0.003, <0.001, and 0.002). Conclusions: CCT and IOP change trends were different. Although IOP decreased from baseline, CCT was unchanged.

Effects of 0.5% tetracaine hydrochloride on central corneal thickness and intraocular pressure

Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330,

Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200,

Asian Biomedicine

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Background: Intraocular pressure (IOP) is the most important risk factor in glaucoma. Before each measurement, anesthetic eye drop must be applied. The effect...

Effects of 0.5% tetracaine hydrochloride on central corneal thickness and intraocular pressure

Article Category: Brief communication (Original)

Published Online: Feb 04, 2017

Page range: 291 - 296

DOI: https://doi.org/10.5372/1905-7415.0602.056

Keywords
Anesthesia, central corneal thickness, glaucoma, intraocular pressure

© 2017

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Effects of 0.5% tetracaine hydrochloride on central corneal thickness and intraocular pressure

Article Category: Brief communication (Original)

Published Online: Feb 04, 2017

Page range: 291 - 296

DOI: https://doi.org/10.5372/1905-7415.0602.056

KeywordsAnesthesia, central corneal thickness, glaucoma, intraocular pressure

© 2017

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Keywords
Anesthesia, central corneal thickness, glaucoma, intraocular pressure