Somatic development and some indices of lipid metabolism in 11-year-old children born with extremely low birth weight (<1000 G) (long-term cohort study)
, , and | Jan 02, 2018
About this article
Article Category: Original articles/Prace oryginalne
Published Online: Jan 02, 2018
Page range: 361 - 368
Received: May 31, 2017
Accepted: Aug 01, 2017
DOI: https://doi.org/10.34763/devperiodmed.20172104.361368
© 2017 Nina Mól, Magdalena Zasada, Małgorzata Klimek, Przemko Kwinta, published by Sciendo
This work is licensed under the Creative Commons Attribution 4.0 International License.
Fig. 1
Baseline characteristics of the study and control population (mean values and standard deviation). Tabela I. Wyjściowa charakterystyka grupy badanej i grupy kontrolnej (dane wyrażone jako średnia i odchylenie standardowe).
| Study group |
Control group |
p-value |
|
|---|---|---|---|
| Gestational age (wk.) |
27.3 (2.3) | 39.8 (1.4) | <0.0001* (1) |
| Birth weight (g) |
843.4(132.4) | 3589.4(538.8) | <0.0001* (1) |
| Gender(boys/girls) |
21/41 | 19/17 | n.s. |
| Cesarean section |
43 | 5 | <0.0001* (2) |
| Infant Small for Gestational Age |
19 | 2 | 0.0045* (2) |
| Newborn – from 1st pregnancy |
23 | 23 | 0,048* (2) |
| Age at 1st assessment (year) |
6.61 (0.36) | 6.98 (0.83) | 0.03* (1) |
| Age at 2nd assessment (year) |
11.06 (0.38) | 10.62 (0.82) | 0.0004* (1) |
Analysis of anthropometric parameters and their comparison between the study group and control group at 11 years old. (mean values and standard deviation). Tabela III. Analiza parametrów antropometrycznych ocenianych w wieku 11 lat w grupie badanej i kontrolnej (dane wyrażone jako średnia i odchylenie standardowe).
| Study group |
Control group |
p-value |
|
|---|---|---|---|
| Height (cm) |
141.7 (7.83) | 146.26 (8.81) | 0.0118* (1) |
| Height z-score |
-0.368 (1.135) | 0.65 (1.081) | <0.0001* (1) |
| Weight (kg) |
33.88 (8.315) | 40.45 (9.96) | 0.0013* (1) |
| Weight z-score |
-0.592 (1.4) | 0.6634 (1.2) | <0.0001* (1) |
| Head circumference (cm) |
51.37 (2.24) | 54.02 (1.42) | <0.0001* (1) |
| Head circumference z-score |
-2.05 (1.63) | -0.33 (0.86) | <0.0001* (1) |
| MUAC (cm) | 20.95 (2.96) | 22.85 (3.66) | 0.0097* (1) |
| Skinfold thickness at triceps (cm) |
1.172 (0.52) | 1.683 (0.7) | 0.0003* (1) |
| Skinfold thickness at triceps z-score |
-0.253 (1.15) | 0.786 (1.123) | <0.0001* (1) |
| Waist circumference (cm) |
61.7 (8.95) | 67.,84 (11.14) | 0.0063* (1) |
| Waist circumference z-score |
0.264 (1.5) | 1.064 (1.41) | 0.0126* (1) |
| BMI (kg/m2) | 16.74 (3.26) | 18.72 (3.4) | 0.0058* (1) |
| BMI z-score | -0.628 (1.6) | 0.364 (1.37) | 0.0023* (1) |
Comparison of changes in values of anthropometric parameters taken at first at 7, and then at 11 years old in the study and control groups (mean values and standard deviation). Tabela IV. Porównanie zmian parametrów antropometrycznych w okresie między 7 a 11 rokiem życia w grupie badanej i kontrolnej (dane wyrażone jako średnia i odchylenie standardowe).
| Difference between 1st and 2nd examination - study group |
Difference between 1st and 2nd examination - control group |
p-value Wartość p | |
|---|---|---|---|
| Height (cm) |
27.95 (15.35) | 21.74 (3.52) | 0.0026 *(1) |
| Height z-score |
0.35 (0.68) | 0.12 (0.33) | 0.0265*(1) |
| Weight (kg) |
14.2 (6.26) | 15.2 (5.74) | 0.4195 (1) |
| Weight z-score |
0.5 (1.02) | 0.24 (0.58) | 0.1118(1) |
| Head circumference (cm) |
1.54 (1.38) | 1.51 (0.71) | 0.9 (1) |
| Head circumference z-score |
0.117 (1.09) | 0.158 (0.44) | 0.7934 (1) |
| MUAC (cm) | 3.39 (2.16) | 3.56 (2.73) | 0.7466 (1) |
| Skinfold thickness at triceps (cm) |
0.41 (0.05) | 0.77 (0.57) | 0.0017 *(1) |
| Skinfold thickness at triceps z-score |
0.56 (0.97) | 1.01 (1.03) | 0.0393* (1) |
| Waist circumference (cm) |
10.23 (5.84) | 12.39 (7.35) | 0.1748 (1) |
| Waist circumference z-score |
1.03 (1.13) | 0.91 (0.165) | 0.6421 (1) |
| BMI (kg/m2) | 2.14 (2.19) | 2.64 (1.71) | 0.215 (1) |
| BMI z-score | 0.34 (1.07) | 0.42 (0.77) | 0.71 (1) |
Analysis of the anthropometric parameters and their comparison between the study group and the control group at 7 years old (mean values and standard deviation). Tabela II. Analiza parametrów antropometrycznych ocenianych w wieku 7 lat w grupie badanej i kontrolnej (dane wyrażone jako średnia i odchylenie standardowe).
| Study group |
Control group |
p-value |
|
|---|---|---|---|
| Height (cm) |
113.749 (15.66) | 124.52 (7.39) | <0.0001* (1) |
| Height z-score |
-0.722 (1.215) | 0.532 (0.934) | <0.0001* (1) |
| Weight (kg) |
19.47 (3.85) | 25.23 (5.35) | <0.0001* (1) |
| Weight z-score |
-1.123 (1.38) | 0.39 (1. 186) | <0.0001* (1) |
| Head circumference (cm) |
49.81 (1.72) | 52.5 (1.33) | <0.0001* (1) |
| Head circumference z-score |
-2.19 (1.33) | -0.377 (0.912) | <0.0001* (1) |
| MUAC (cm) | 17.51 (1.97) | 19.29 (2.675) | 0.0009* (1) |
| Skinfold thickness at triceps (cm) |
0.76 (0.29) | 0.92 (0.3) | 0.0144* (1) |
| Skinfold thickness at triceps z-score |
-0.817 (0.98) | -0.191 (1.08) | 0.0065* (1) |
| Waist circumference (cm) |
50.14 (4.75) | 55.45 (6.56) | 0.0002* (1) |
| Waist circumference z-score |
-0.836 (1.314) | 0.34 (1.38) | 0.0006* (1) |
| BMI (kg/m2) | 14.5 (1.98) | 16.16 (2.34) | 0.0007* (1) |
| BMI z-score | -0.999 (1.465) | 0.12 (1.334) | 0.0002* (1) |
Analysis of changes in lipid profile in period of time between 7 and 11 years old. Tabela V. Analiza zmian profilu lipidowego w okresie między 7 a 11 rokiem życia w grupie badanej i kontrolnej.
| Difference between 1st and 2nd examination - study group |
Difference between 1st and 2nd examination - control group |
p-value | |
|---|---|---|---|
| LDL (mmol/l) | -0.25 | -0.24 | 0.9140 (1) |
| HDL (mmol/l) | 0.016 | 0.08 | 0.5500 (1) |
| TG (mmol/l) | -0.004 | 0.16 | 0.3000 (1) |
| Total Cholesterol (mmol/l) | -0.4 | -0.13 | 0.0530 (1) |