<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Circadian rhythms influence various aspects of the biology and physiology of the host, such as food intake and sleep/wake cycles. In recent years, an increasing amount of genetic and epidemiological data has shown that the light/dark cycle is the main cue that regulates circadian rhythms. Other factors, including sleep/wake cycles and food intake, have necessary effects on the composition and rhythms of the gut microbiota. Interestingly, the gut microbiota can affect the circadian rhythm of hosts in turn through contact-dependent and contact-independent mechanisms. Furthermore, the gut microbiota has been shown to regulate the sleep/wake cycles through gut-brain-microbiota interaction. In addition to diabetes, the gut microbiota can also intervene in the progression of neuro- degenerative diseases through the gut-brain-microbiota interaction, and also in other diseases such as hypertension and rheumatoid arthritis, where it is thought to have a spare therapeutic potential. Even though fecal microbiota transplantation has good potential for treating many diseases, the risk of spreading intestinal pathogens should not be ignored.
<fig id="j_pjm-2023-046_fig_002" position="float" fig-type="figure">
<graphic xmlns:xlink="http://www.w3.org/1999/xlink" xlink:href="graphic/j_pjm-2023-046_fig_002.jpg"></graphic>
</fig></p>
</abstract>

Circadian rhythms influence various aspects of the biology and physiology of the host, such as food intake and sleep/wake cycles. In recent years, an increasing amount of genetic and epidemiological data has shown that the light/dark cycle is the main cue that regulates circadian rhythms. Other factors, including sleep/wake cycles and food intake, have necessary effects on the composition and rhythms of the gut microbiota. Interestingly, the gut microbiota can affect the circadian rhythm of hosts in turn through contact-dependent and contact-independent mechanisms. Furthermore, the gut microbiota has been shown to regulate the sleep/wake cycles through gut-brain-microbiota interaction. In addition to diabetes, the gut microbiota can also intervene in the progression of neuro- degenerative diseases through the gut-brain-microbiota interaction, and also in other diseases such as hypertension and rheumatoid arthritis, where it is thought to have a spare therapeutic potential. Even though fecal microbiota transplantation has good potential for treating many diseases, the risk of spreading intestinal pathogens should not be ignored.

New Awareness of the Interplay Between the Gut Microbiota and Circadian Rhythms

Polish Journal of Microbiology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"New Awareness of the Interplay Between the Gut Microbiota and Circadian Rhythms"}

Circadian rhythms influence various aspects of the biology and physiology of the host, such as food intake and sleep/wake cycles. In recent years, an...

New Awareness of the Interplay Between the Gut Microbiota and Circadian Rhythms

Article Category: MINIREVIEW

Published Online: Dec 16, 2023

Page range: 355 - 363

Received: Aug 06, 2023

Accepted: Oct 27, 2023

DOI: https://doi.org/10.33073/pjm-2023-046

Keywords
circadian rhythm, the gut microbiota, metabolism, gut-brain-microbiota interaction, fecal microbiota transplantation

© 2023 Xiaoxiao Pang et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

New Awareness of the Interplay Between the Gut Microbiota and Circadian Rhythms

Article Category: MINIREVIEW

Published Online: Dec 16, 2023

Page range: 355 - 363

Received: Aug 06, 2023

Accepted: Oct 27, 2023

DOI: https://doi.org/10.33073/pjm-2023-046

Keywordscircadian rhythm, the gut microbiota, metabolism, gut-brain-microbiota interaction, fecal microbiota transplantation

© 2023 Xiaoxiao Pang et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
circadian rhythm, the gut microbiota, metabolism, gut-brain-microbiota interaction, fecal microbiota transplantation