<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Bisphenol A (BPA) is an industrial chemical used as an additive in conventional point-of-sale thermal paper receipts, in the production of many polycarbonate plastics, and epoxy resins lignin for food. BPA is xenoestrogen, a foreign compound that is not naturally produced in living organisms, but which acts similarly to natural 17-ß estradiol (natural estrogen). Due to its weak estrogenic activities, BPA exposure may influence multiple endocrine-related pathway, and is associated with prostate and breast cancer, neurobehavioral deficits, heart disease, and obesity. Furthermore, BPA may act as a DNA methylation agent and cause altered gene expression in the brain. Human exposure to bisphenol A is a matter of controversy. This review shows a potential risks in workplace resulting from contact with bisphenol A. The work presents the contribution of BPA exposure levels via dermal contact and the relationship between BPA exposure level and oxidative DNA damage.</p></abstract>

Bisphenol A (BPA) is an industrial chemical used as an additive in conventional point-of-sale thermal paper receipts, in the production of many polycarbonate plastics, and epoxy resins lignin for food. BPA is xenoestrogen, a foreign compound that is not naturally produced in living organisms, but which acts similarly to natural 17-ß estradiol (natural estrogen). Due to its weak estrogenic activities, BPA exposure may influence multiple endocrine-related pathway, and is associated with prostate and breast cancer, neurobehavioral deficits, heart disease, and obesity. Furthermore, BPA may act as a DNA methylation agent and cause altered gene expression in the brain. Human exposure to bisphenol A is a matter of controversy. This review shows a potential risks in workplace resulting from contact with bisphenol A. The work presents the contribution of BPA exposure levels via dermal contact and the relationship between BPA exposure level and oxidative DNA damage.

Identification of health risks from harmful chemical agents – review concerning bisphenol A in workplace

Department of Production Engineering and Safety

Faculty of Natural Sciences and Technology

Production Engineering Archives

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Bisphenol A (BPA) is an industrial chemical used as an additive in conventional point-of-sale thermal paper receipts, in the production of many polycarbonate...

Identification of health risks from harmful chemical agents – review concerning bisphenol A in workplace

Published Online: Jun 25, 2020

Page range: 45 - 49

Received: Mar 10, 2020

Accepted: May 21, 2020

DOI: https://doi.org/10.30657/pea.2020.26.10

Keywords
bisphenol A, health risk, harmful chemical agents, human exposure, DNA oxidative damage

© 2020 Katarzyna Kapustka et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Identification of health risks from harmful chemical agents – review concerning bisphenol A in workplace

Published Online: Jun 25, 2020

Page range: 45 - 49

Received: Mar 10, 2020

Accepted: May 21, 2020

DOI: https://doi.org/10.30657/pea.2020.26.10

Keywordsbisphenol A, health risk, harmful chemical agents, human exposure, DNA oxidative damage

© 2020 Katarzyna Kapustka et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
bisphenol A, health risk, harmful chemical agents, human exposure, DNA oxidative damage