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In this article automatization of road transport is investigated. In the first chapter relevant international trends were identified. In this paper the research hypothesis is that in the case of automatized road vehicles there is a significant likelihood of endangering human life. Secondly, the history of road safety is shortly described, especially focusing on vehicle design and sweep of system’s theory. In the third chapter evolution of drivers’ assistance systems were elaborated, emphasizing especially autonomous vehicles. Finally, in conclusion the authors warn that new technological solutions could pose new threats.