<abstract xmlns="http://www.w3.org/1999/xhtml"><p>The solubilisation of natural compound, (+)-usnic acid, in micellar solutions of gemini (<italic>N</italic>,<italic>N’</italic>-didecyl-<italic>N</italic>,<italic>N</italic>,<italic>N’</italic>,<italic>N’</italic>-tetramethylethane-1,2-diyldiammonium dibromide) and heterogemini (decyl 2-[decyl(dimethyl)ammonio]ethylphosphate) surfactants and their equimolar mixture has been studied. The highest solubility was found for gemini surfactant. The relationship between synergism in surface properties of mixture of surfactants and their solubilisation properties is also discussed.</p></abstract>

The solubilisation of natural compound, (+)-usnic acid, in micellar solutions of gemini (N,N’-didecyl-N,N,N’,N’-tetramethylethane-1,2-diyldiammonium dibromide) and heterogemini (decyl 2-[decyl(dimethyl)ammonio]ethylphosphate) surfactants and their equimolar mixture has been studied. The highest solubility was found for gemini surfactant. The relationship between synergism in surface properties of mixture of surfactants and their solubilisation properties is also discussed.

Solubilisation of (+)-Usnic Acid in Aqueous Micellar Solutions of Gemini and Heterogemini Surfactants and their Equimolar Mixture

Comenius University in Bratislava, Faculty of Pharmacy, Department of Chemical Theory of Drugs, Kalinčiakova 8, 832 32, Bratislava, Slovak Republic

Comenius University in Bratislava, Faculty of Pharmacy, Department of Chemical Theory of Drugs

European Pharmaceutical Journal

The solubilisation of natural compound, (+)-usnic acid, in micellar solutions of gemini (N,N’-didecyl-N,N,N’,N’-tetramethylethane-1,2-diyldiammonium dibromide)...

Solubilisation of (+)-Usnic Acid in Aqueous Micellar Solutions of Gemini and Heterogemini Surfactants and their Equimolar Mixture

Published Online: Dec 28, 2012

Page range: 36 - 43

DOI: https://doi.org/10.2478/v10219-012-0022-8

This content is open access.