<abstract xmlns="http://www.w3.org/1999/xhtml"><p> Breast cancer has high incidence and still significant mortality. Due to the widespread application and efficacy of surgery in breast cancer treatment, the surgeon has a crucial role in the treatment planning. Taking into account the tendency to personalized cancer care and the heterogeneity of breast cancer, the surgeon has to be aware about the prognostic and predictive characteristics of breast cancer. We discuss here the classaic pathology of breast cancer along with molecular subtypes, novel prognostic markers and molecular pathogenesis.</p></abstract>

Breast cancer has high incidence and still significant mortality. Due to the widespread application and efficacy of surgery in breast cancer treatment, the surgeon has a crucial role in the treatment planning. Taking into account the tendency to personalized cancer care and the heterogeneity of breast cancer, the surgeon has to be aware about the prognostic and predictive characteristics of breast cancer. We discuss here the classaic pathology of breast cancer along with molecular subtypes, novel prognostic markers and molecular pathogenesis.

Pathology of Breast Cancer: from Classic Concepts to Molecular Pathology and Pathogenesis

Department of Pathology, Riga Stradins University, Riga, Latvia

Institute of Oncology, Riga Stradins University, Riga, Latvia

Department of Surgery, Riga Stradins University, Riga, Latvia

Acta Chirurgica Latviensis

Breast cancer has high incidence and still significant mortality. Due to the widespread application and efficacy of surgery in breast cancer treatment, the...

Pathology of Breast Cancer: from Classic Concepts to Molecular Pathology and Pathogenesis

Published Online: May 11, 2013

Page range: 59 - 66

DOI: https://doi.org/10.2478/v10163-012-0012-x

This content is open access.