<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>Allergic asthma is the most frequent disease of the respiratory tract. The aim of the current experimental and clinical studies was to find new sources of drugs able to control asthmatic inflammation and airway hyperresponsiveness. Our experimental studies were focused on efficiency evaluation of substances able to influence activities of ion channels, phosphodiesterase (PDE) isoforms, substances from the group of polyphenols and NO metabolism modulators during experimentally induced allergic asthma.</p></abstract>

Allergic asthma is the most frequent disease of the respiratory tract. The aim of the current experimental and clinical studies was to find new sources of drugs able to control asthmatic inflammation and airway hyperresponsiveness. Our experimental studies were focused on efficiency evaluation of substances able to influence activities of ion channels, phosphodiesterase (PDE) isoforms, substances from the group of polyphenols and NO metabolism modulators during experimentally induced allergic asthma.

Pharmacologic modulation of experimentally induced allergic asthma

Department of Pharmacology, Jessenius Faculty of Medicine, Comenius University, Martin, Slovakia

Interdisciplinary Toxicology

{"article-title":"Pharmacologic modulation of experimentally induced allergic asthma"}

Allergic asthma is the most frequent disease of the respiratory tract. The aim of the current experimental and clinical studies was to find new sources of...

Pharmacologic modulation of experimentally induced allergic asthma

Published Online: Apr 18, 2011

Page range: 27 - 32

DOI: https://doi.org/10.2478/v10102-011-0006-x

Keywords
allergic asthma, nitric oxide, ion channels, PDE, polyphenols

This content is open access.

Pharmacologic modulation of experimentally induced allergic asthma

Published Online: Apr 18, 2011

Page range: 27 - 32

DOI: https://doi.org/10.2478/v10102-011-0006-x

Keywordsallergic asthma, nitric oxide, ion channels, PDE, polyphenols

This content is open access.

Keywords
allergic asthma, nitric oxide, ion channels, PDE, polyphenols