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Journals
Interdisciplinary Toxicology
Volume 1 (2008): Issue 2 (September 2008)
Open Access
Ellipticine and benzo(a)pyrene increase their own metabolic activation via modulation of expression and enzymatic activity of cytochromes P450 1A1 and 1A2
Dagmar Aimová
Dagmar Aimová
,
Jitka Poljaková
Jitka Poljaková
,
Věra Kotrbová
Věra Kotrbová
,
Michaela Moserová
Michaela Moserová
,
Eva Frei
Eva Frei
,
Volker Arlt
Volker Arlt
and
Marie Stiborová
Marie Stiborová
| Nov 01, 2010
Interdisciplinary Toxicology
Volume 1 (2008): Issue 2 (September 2008)
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Published Online:
Nov 01, 2010
Page range:
160 - 168
DOI:
https://doi.org/10.2478/v10102-010-0033-z
Keywords
benzo(a)pyrene
,
ellipticine
,
induction
,
cytochromes P450
,
NADPH:cytochrome P450 reductase
,
HRN™
,
mice
This content is open access.
Dagmar Aimová
Department of Biochemistry, Faculty of Science, Charles University, Prague, Albertov 2030, 128 40 Prague 2, Czech Republic
Jitka Poljaková
Department of Biochemistry, Faculty of Science, Charles University, Prague, Albertov 2030, 128 40 Prague 2, Czech Republic
Věra Kotrbová
Department of Biochemistry, Faculty of Science, Charles University, Prague, Albertov 2030, 128 40 Prague 2, Czech Republic
Michaela Moserová
Department of Biochemistry, Faculty of Science, Charles University, Prague, Albertov 2030, 128 40 Prague 2, Czech Republic
Eva Frei
Division of Molecular Toxicology, German Cancer Research Center, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
Volker Arlt
Section of Molecular Carcinogenesis, Institute of Cancer Research, Brookes Lawley Building, Sutton, Surrey SM2 5NG, United Kingdom
Marie Stiborová
Department of Biochemistry, Faculty of Science, Charles University, Prague, Albertov 2030, 128 40 Prague 2, Czech Republic