<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>The contact of a biomaterial with the biological environment in in vitro and in vivo tests leads to the production of a particular ecosystem in which the active roles perform both, the material surface and the extracellular matrix protein forming a biofilm. Proteins affect cell and bacteria adhesion processes, biological activity of cells and activation of inflammatory response.</p><p>The knowledge of the reaction mechanisms active on the surface of the material and the contacting tissues enables definite modification of the material surface layer eliminating their disadvantages, giving new, desired properties, affecting the biology of cells. Testing the biocompatibility of titanium materials emphasises their reactivity with proteins and cells and the possibility of modifying the biological reactivity of the surface by changing its properties by biochemical and surface engineering methods. This article presents results of previous studies on this problem.</p></abstract>

The contact of a biomaterial with the biological environment in in vitro and in vivo tests leads to the production of a particular ecosystem in which the active roles perform both, the material surface and the extracellular matrix protein forming a biofilm. Proteins affect cell and bacteria adhesion processes, biological activity of cells and activation of inflammatory response.The knowledge of the reaction mechanisms active on the surface of the material and the contacting tissues enables definite modification of the material surface layer eliminating their disadvantages, giving new, desired properties, affecting the biology of cells. Testing the biocompatibility of titanium materials emphasises their reactivity with proteins and cells and the possibility of modifying the biological reactivity of the surface by changing its properties by biochemical and surface engineering methods. This article presents results of previous studies on this problem.

Reactions on the Surface of the Implant Under the Influence of Biofilm

Faculty of Mechanical Engineering, Technical University of Gdansk, Narutowicza 11/12, 80-233 Gdansk, Poland

Advances in Materials Science

{"article-title":"Reactions on the Surface of the Implant Under the Influence of Biofilm"}

The contact of a biomaterial with the biological environment in in vitro and in vivo tests leads to the production of a particular ecosystem in which the...

Reactions on the Surface of the Implant Under the Influence of Biofilm

Published Online: Jan 28, 2011

Page range: 5 - 11

DOI: https://doi.org/10.2478/v10077-010-0011-3

Keywords
biofilm, implants

This content is open access.

Reactions on the Surface of the Implant Under the Influence of Biofilm

Published Online: Jan 28, 2011

Page range: 5 - 11

DOI: https://doi.org/10.2478/v10077-010-0011-3

Keywordsbiofilm, implants

This content is open access.

Keywords
biofilm, implants