<abstract xmlns="http://www.w3.org/1999/xhtml"><p> Currently available approaches for treating patients with ischemic heart disease include medical therapy or coronary revascularization by surgical procedures, like coronary artery bypass grafting (CABG). Bypass grafting often provides dramatic relief from the symptoms of myocardial ischemia. However, a significant number of patients are not candidates for these kind of treatment or achieve incomplete revascularization. Hence, an alternative treatment strategy such as therapeutic angiogenesis has emerged as a new method for patients with inoperable coronary artery disease. Recently it has been demonstrated that angiogenic growth factors, like vascular endothelial growth factor or fibroblast growth factor, can improve myocardial perfusion and function.</p></abstract>

Currently available approaches for treating patients with ischemic heart disease include medical therapy or coronary revascularization by surgical procedures, like coronary artery bypass grafting (CABG). Bypass grafting often provides dramatic relief from the symptoms of myocardial ischemia. However, a significant number of patients are not candidates for these kind of treatment or achieve incomplete revascularization. Hence, an alternative treatment strategy such as therapeutic angiogenesis has emerged as a new method for patients with inoperable coronary artery disease. Recently it has been demonstrated that angiogenic growth factors, like vascular endothelial growth factor or fibroblast growth factor, can improve myocardial perfusion and function.

The Most Important Angiogenic Growth Factors Influencing the Development and Function of Blood Vessels - in the Context of Coronary Artery Bypass Grafting (CABG)

Department of Histology and Embryology, Poznan University of Medical Sciences, Swiecicki Str. 660-781 Poznan, Poland

Department of Histology and Embryology, University of Medical Sciences, Poznan, Poland Regional Specialized Hospital in Wroclaw, Research and Development Center, Wroclaw, Poland

Department of Histology and Embryology, University of Medical Sciences, Poznan, Poland

Medical Journal of Cell Biology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Currently available approaches for treating patients with ischemic heart disease include medical therapy or coronary revascularization by surgical procedures,...

The Most Important Angiogenic Growth Factors Influencing the Development and Function of Blood Vessels - in the Context of Coronary Artery Bypass Grafting (CABG)

Published Online: Oct 15, 2014

Page range: 55 - 67

DOI: https://doi.org/10.2478/v10052-011-0004-3

Keywords
coronary artery disease (CAD), coronary artery bypass grafting (CABG), angiogenic growth factors

© by Karolina Sterzynska

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The Most Important Angiogenic Growth Factors Influencing the Development and Function of Blood Vessels - in the Context of Coronary Artery Bypass Grafting (CABG)

Published Online: Oct 15, 2014

Page range: 55 - 67

DOI: https://doi.org/10.2478/v10052-011-0004-3

Keywordscoronary artery disease (CAD), coronary artery bypass grafting (CABG), angiogenic growth factors

© by Karolina Sterzynska

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
coronary artery disease (CAD), coronary artery bypass grafting (CABG), angiogenic growth factors