<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>Patients who undergo radiofrequency ablation of the atrioventricular (AV) node rarely develop acute major complications. A 41-year-old Caucasian male smoker, was admitted to the Pulmology Teaching Hospital at Belgrade, Serbia, for sharp persistent chest pain, fever and fatigue following AV node radiofrequency ablation for arrhythmia. Chest X-ray showed obtuse right costo-phrenic angle and laminar atelectasis in the right lower lung lobe. The plasma D-dimer level was elevated. A perfusion lung scan showed multiple bilateral perfusion defects and multislice computed tomography showed thrombotic mass in the right pulmonary artery. Genetic analysis revealed that he was heterozygous for the prothrombin Factor V (FV) Leiden and MTHFR C677T mutations. Therapy started with intravenous heparin, followed by warfarin. He had no other episodes over a 2-year follow-up. Lifelong oral anticoagulant therapy was recommended.</p></abstract>

Patients who undergo radiofrequency ablation of the atrioventricular (AV) node rarely develop acute major complications. A 41-year-old Caucasian male smoker, was admitted to the Pulmology Teaching Hospital at Belgrade, Serbia, for sharp persistent chest pain, fever and fatigue following AV node radiofrequency ablation for arrhythmia. Chest X-ray showed obtuse right costo-phrenic angle and laminar atelectasis in the right lower lung lobe. The plasma D-dimer level was elevated. A perfusion lung scan showed multiple bilateral perfusion defects and multislice computed tomography showed thrombotic mass in the right pulmonary artery. Genetic analysis revealed that he was heterozygous for the prothrombin Factor V (FV) Leiden and MTHFR C677T mutations. Therapy started with intravenous heparin, followed by warfarin. He had no other episodes over a 2-year follow-up. Lifelong oral anticoagulant therapy was recommended.

Pulmonary Thromboembolism Following Radio-Frequency Ablation of the Atrioventricular Node in a Patient Heterozygous for the Factor V Leiden and the Mthfr C677T Mutations

Internal Medicine Department, School of Medicine, University of Belgrade, Belgrade, Serbia

Teaching Hospital of Lung Diseases, Research and Epidemiology Department, Clinical Centre of Serbia, Belgrade, Serbia

Clinical Centre of Serbia, Centre of Radiology and Magnetic Resonance, Belgrade, Serbia

Balkan Journal of Medical Genetics

Patients who undergo radiofrequency ablation of the atrioventricular (AV) node rarely develop acute major complications. A 41-year-old Caucasian male smoker,...

Pulmonary Thromboembolism Following Radio-Frequency Ablation of the Atrioventricular Node in a Patient Heterozygous for the Factor V Leiden and the Mthfr C677T Mutations

Published Online: Jul 25, 2011

Page range: 51 - 55

DOI: https://doi.org/10.2478/v10034-011-0018-z

Keywords
Thromboembolism, Radiofrequency ablation, Atrioventricular (AV) node, Factor V (FV) Leiden mutation, Risk factor

This content is open access.

Pulmonary Thromboembolism Following Radio-Frequency Ablation of the Atrioventricular Node in a Patient Heterozygous for the Factor V Leiden and the Mthfr C677T Mutations

Published Online: Jul 25, 2011

Page range: 51 - 55

DOI: https://doi.org/10.2478/v10034-011-0018-z

KeywordsThromboembolism, Radiofrequency ablation, Atrioventricular (AV) node, Factor V (FV) Leiden mutation, Risk factor

This content is open access.

Keywords
Thromboembolism, Radiofrequency ablation, Atrioventricular (AV) node, Factor V (FV) Leiden mutation, Risk factor