<abstract xmlns="http://www.w3.org/1999/xhtml"><p>In vitro dose-response relationships are used to describe the relation between dicentric chromosomes and radiation dose for human peripheral blood lymphocytes. The dicentric yield depends on both the dose and the radiation quality. Thus, for reliable dose estimation in vitro dose responses must be determined for different radiation qualities. This paper reports the work for setting up the relationship for the dicentric production in the lymphocytes exposed in vitro to 192Ir g-rays at Central Laboratory for Radiological Protection (CLOR). In a case of a radiation accident in industrial radiography using 192Ir sealed sources, this will be the basis for the indirect evaluation of the g-ray dose to which an accidental victim was exposed.</p></abstract>

In vitro dose-response relationships are used to describe the relation between dicentric chromosomes and radiation dose for human peripheral blood lymphocytes. The dicentric yield depends on both the dose and the radiation quality. Thus, for reliable dose estimation in vitro dose responses must be determined for different radiation qualities. This paper reports the work for setting up the relationship for the dicentric production in the lymphocytes exposed in vitro to 192Ir g-rays at Central Laboratory for Radiological Protection (CLOR). In a case of a radiation accident in industrial radiography using 192Ir sealed sources, this will be the basis for the indirect evaluation of the g-ray dose to which an accidental victim was exposed.

Establishment of in vitro 192Ir γ-ray dose-response relationship for dose assessment by the lymphocyte dicentric assay

Central Laboratory for Radiological Protection Konwaliowa 7, 02-194 Warsaw, Poland

Polish Journal of Medical Physics and Engineering

In vitro dose-response relationships are used to describe the relation between dicentric chromosomes and radiation dose for human peripheral blood lymphocytes....

Establishment of in vitro 192Ir γ-ray dose-response relationship for dose assessment by the lymphocyte dicentric assay

Published Online: Feb 26, 2013

Page range: 11 - 21

DOI: https://doi.org/10.2478/v10013-012-0003-1

Keywords
biodosimetry, cytogenetic analysis, radiation exposure

This content is open access.

Establishment of in vitro 192Ir γ-ray dose-response relationship for dose assessment by the lymphocyte dicentric assay

Published Online: Feb 26, 2013

Page range: 11 - 21

DOI: https://doi.org/10.2478/v10013-012-0003-1

Keywordsbiodosimetry, cytogenetic analysis, radiation exposure

This content is open access.

Keywords
biodosimetry, cytogenetic analysis, radiation exposure