1. C. V. Pardeshi, P. V. Rajput, V. S. Belgamwar and A. R. Tekade, Formulation, optimization and evaluation of spray-dried mucoadhesive microspheres as intranasal carriers for valsartan, J. Microencapsul. 29 (2011) 103-114; DOI: 10.3109/02652048.2011.630106.10.3109/02652048.2011.630106Search in Google Scholar

2. W. Mehnert and K. Mader, Solid lipid nanoparticles: Production, characterization and applications, Adv. Drug. Del. Rev. 47 (2001) 165-196; DOI: 10.1016/S0169-409X(01)00105-3.10.1016/S0169-409X(01)00105-3Search in Google Scholar

3. S. Mukherjee, S. Ray and R. S. Thakur, Solid lipid nanoparticles: A modern formulation approach in drug delivery system, Ind. J. Pharm. Sci. 71 (2009) 349-358.Search in Google Scholar

4. R. H. Müller, K. Mäder and S. Gohla, Solid lipid nanoparticles (SLN) for controlled drug delivery - A review of the state of the art, Eur. J. Pharm. Biopharm. 50 (2000) 161-177.10.1016/S0939-6411(00)00087-4Search in Google Scholar

5. R. H. Müller, M. Radtke and S. A. Wissing, Nanostructured lipid matrices for improved microencapsulation of drugs, Int. J. Pharm. 242 (2002) 121-128; DOI: 10.1016/S0378-5173(02)00180-1.10.1016/S0378-5173(02)00180-1Search in Google Scholar

6. R. H. Müller, M. Radtke and S. A. Wissing, Solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) in cosmetic and dermatological preparations, Adv. Drug Del. Rev. 54 (Suppl. 1) (2002) S131-S155; DOI: 10.1016/S0169-409X(02)00118-7.10.1016/S0169-409X(02)00118-7Search in Google Scholar

7. R. H. Müller, R. D. Petersen, A. Hommoss and J. Pardeike, Nanostructured lipid carriers (NLC) for cosmetic dermal products, Adv. Drug Del. Rev. 59 (2007) 522-530; DOI: 10.1016/j.addr.2007.04.012.10.1016/j.addr.2007.04.01217602783Search in Google Scholar

8. J. Y. Fang, C. L. Fang, C. H. Liu and Y. H. Su, Lipid nanoparticles as vehicles for psoralen delivery: Solid lipid nanoparticles (SLN) versus nanostructured lipid carriers, Eur. J. Pharm. Biopharm. 70 (2008) 633-640; DOI: 10.1016/j.ejpb.2008.05.008.10.1016/j.ejpb.2008.05.00818577447Search in Google Scholar

9. E. B. Souto, S. A. Wissing, C. M. Barbosa and R. H. Müller, Development of a controlled release formulation based on SLN and NLC for topical clotrimazole delivery, Int. J. Pharm. 278 (2004) 71-77; DOI: 10.1016/j.ijpharm.2004.02.032.10.1016/j.ijpharm.2004.02.03215158950Search in Google Scholar

10. M. Joshi and V. Patravale, Nanostructured lipid carriers (NLC) based gel of celecoxib, Int. J. Pharm. 346 (2008) 124-132; DOI: 10.1016/j.ijpharm.2007.05.060.10.1016/j.ijpharm.2007.05.06017651933Search in Google Scholar

11. V. Teeranachaideekul, R. H. Müller and V. B. Junyaprasert, Encapsulation of ascorbyl palmitate in nanostructured lipid carriers (NLC) - Effect of formulation parameters on physicochemical stability, Int. J. Pharm. 340 (2007) 198-206; DOI: 10.1016/j.ijpharm.2007.03.022.10.1016/j.ijpharm.2007.03.02217482778Search in Google Scholar

12. S. Doktorovova, J. Araujo, M. L. Garcia, E. Rakovsky and E. B. Souto, Formulating fluticasone propionate in novel PEG-containing nanostructured lipid carriers (PEG-NLC), Colloid Surfacec B. 75 (2010) 538-542; DOI: 10.1016/j.colsurfb.2009.09.033.10.1016/j.colsurfb.2009.09.033Search in Google Scholar

13. C. Olbrich, A. Gessner, W. Schroder, O. Kayser and R. H. Müller, Lipid-drug conjugate of the hydrophilic drug diminazine-cytotoxicity testing and mouse serum adsorption, J. Control. Release 96 (2004) 425-435; DOI: 10.1016/j.jconrel.2004.02.024.10.1016/j.jconrel.2004.02.024Search in Google Scholar

14. H. L. Wong, A. M. Rauth, R. Bendayan and X. Y. Wu, In-vivo evaluation of a new polymer-lipid hybrid nanoparticle (PLN) formulation of doxorubicin in a murine solid tumor model, Eur. J. Pharm. Biopharm. 65 (2007) 300-308; DOI: 10.1016/j.ejpb.2006.10.022.10.1016/j.ejpb.2006.10.022Search in Google Scholar

15. H. L. Wong, A. M. Rauth, R. Bendayan and X. Y. Wu, Simultaneous delivery of doxorubicin and GG918 (Elacridar) by new polymer-lipid hybrid nanoparticles (PLN) for enhanced treatment for multidrug-resistant breast cancer, J. Control. Release 116 (2006) 275-284; DOI: 10.1016/j.jconrel.2006.09.007.10.1016/j.jconrel.2006.09.007Search in Google Scholar

16. L. Zhang, J. M. Chan, F. X. Gu, A. Z. Wang, A. F. Radovic-Moreno, F. Alexis, R. Langer and O. C. Farokhzad, Self-assembled lipid-polymer hybrid nanoparticles: A robust drug delivery platform, ACS Nano. 2 (2008) 1696-1702; DOI: 10.1021/nn800275r.10.1021/nn800275rSearch in Google Scholar

17. Y. Li, H. L. Wong, A. J. Shuhendler, A. M. Rauth and X. Y. Wu, Molecular interactions, internal structure and drug release kinetics of rationally developed polymer-lipid hybrid nanoparticles, J. Control. Release. 128 (2008) 60-70; DOI: 10.1016/j.jconrel.2008.02.014.10.1016/j.jconrel.2008.02.014Search in Google Scholar

18. C. Salvador-Morales, L. Zhang, R. Langer and O. C. Farokhzad, Immunocompatibility properties of polymer-lipid hybrid nanoparticles with heterogeneous surface functional groups, Biomaterials 30 (2009) 2231-2240; DOI: 10.1016/j.biomaterials.2009.01.005.10.1016/j.biomaterials.2009.01.005Search in Google Scholar

19. R. Lander, W. Manger, M. Scouloudis, A. Ku, C. Davis and A. Lee, Gaulin homogenization: a mechanistic study, Biotechnol. Prog. 16 (2000) 80-85; DOI: 10.1021/bp990135c.10.1021/bp990135cSearch in Google Scholar

20. R. H. Müller, S. Benita and B. Bohm, Emulsions and nanosuspensions for the formulation of poorly soluble drugs, Int. J. Pharm. 212 (2001) 143-144.10.1016/S0378-5173(00)00604-9Search in Google Scholar

21. B. Siekmann and K. Westesen, Solid lipid nanoparticles stabilized by tyloxapol, Eur. J. Pharm. Sci. 2 (1994) 117-194; DOI: 10.1016/0928-0987(94)90407-3.10.1016/0928-0987(94)90407-3Search in Google Scholar

22. H. Bunjes, B. Siekmann and K. Westesen, Emulsions of supercooled melts-a novel drug delivery system, in Submicron Emulsions in Drug Targeting and Delivery, Ed. S. Benita, Hardwood Academic Publishers, Amsterdam 1998, pp. 175-204.10.1201/9780367810528-7Search in Google Scholar

23. V. Venkateswarlu and K. Manjunath, Preparation, characterization and in-vitro release kinetics of clozapine solid lipid nanoparticles, J. Control. Release 95 (2004) 627-638; DOI: 10.1016/j.jconrel.2004.01.005.10.1016/j.jconrel.2004.01.005Search in Google Scholar

24. S. Gande, V. Vobalaboina, M. Kopparam, V. Venkateswarlu and S. Vemula, Preparation, characterization, and in vitro and in vivo evaluation of lovastatin solid lipid nanoparticles, AAPS PharmSciTech. 8 (2007) E1-E9.10.1208/pt0801024Search in Google Scholar

25. S. P. Vyas and R. K. Khar, Targeted and Controlled Drug Delivery: A Novel Carrier System, 1st ed., CBS Publishers and Distributors, New Delhi 2002, pp. 346-348.Search in Google Scholar

26. S. Xie, L. Zhu, Z. Dong, X. Wang, Y. Wang, X. Li and W. Zhou, Preparation, characterization and pharmacokinetics of enrofloxacin loaded solid lipid nanoparticles: Influences of fatty acids, Colloid Surface B 83 (2011) 382-387; DOI: 10.1016/j.colsurfb.2010.12.014; DOI: 10.1016/j.colsurfb.2010.12.014.Search in Google Scholar

27. A. V. Heydenreich, R. Westmeier, N. Pedersen, H. S. Poulsen and H. G. Kristensen, Preparation and purification of cationic solid lipid nanospheres-effects on particle size, physical stability and cell toxicity, Int. J. Pharm. 254 (2003) 83-87; DOI: 10.1016/S0378-5173(02)00688-9.10.1016/S0378-5173(02)00688-9Search in Google Scholar

28. N. K. Jain, Advances in Controlled and Novel Drug Delivery, 1st ed., CBS Publishers and Distributors, New Delhi 2001, pp. 418-424.Search in Google Scholar

29. H. Zhou, T. Gu, D. Yang, Z. Jiang and J. Zeng, Griseofulvin solid lipid nanoparticles based on microemulsion technique, Adv. Mater. Res. 197-198 (2011) 47-50; DOI: 10.4028/www.scientific.net/AMR.197-198.47.10.4028/www.scientific.net/AMR.197-198.47Search in Google Scholar

30. M. R. Gasco and L. P. Antonelli, Method for producing solid lipid nanospheres having a narrow size distribution, US Pat. 5,250,236, 05 Oct. 1993.Search in Google Scholar

31. S. Morel, M. R. Gasco and R. Cavalli, Incorporation in lipospheres of [D-Trp-6]LHRH, Int. J. Pharm. 105 (1994) RI-R3; DOI: 10.1016/0378-5173(94)90466-9.10.1016/0378-5173(94)90466-9Search in Google Scholar

32. S. Morel, E. Ugazio, R. Cavalli and M. R. Gasco, Thymopentin in solid lipid nanoparticles, Int. J. Pharm. 132 (1996) 259-261; DOI: 10.1016/0378-5173(95)04388-8.10.1016/0378-5173(95)04388-8Search in Google Scholar

33. T. Hammady, A. El-Gindy, E. Lejmi, R. S. Dhanikula, P. Moreau and P. Hildgen, Characteristics and properties of nanospheres co-loaded with lipophilic and hydrophilic drug models, Int. J. Pharm. 369 (2009) 185-195; DOI: 10.1016/j.ijpharm.2008.10.034.10.1016/j.ijpharm.2008.10.034Search in Google Scholar

34. M. Trotta, F. Debernardi and O. Caputo, Preparation of solid lipid nanoparticles by solvent emulsification-diffusion technique, Int. J. Pharm. 257 (2003) 153-160; DOI: 10.1016/S0378-5173(03)00135-2.10.1016/S0378-5173(03)00135-2Search in Google Scholar

35. L. Battaglia, M. Trotta, M. M. E. G. P. A. Solid lipid nanoparticles formed by solvent-in-eater emulsion-diffusion technique, J. Microencapsul. 5 (2009) 394-402.Search in Google Scholar

36. H. Yuan, L. F. Huang, Y. Z. Du, X. Y. Ying, J. You, F. Q. Hu and S. Zeng, Solid lipid nanoparticles prepared by solvent diffusion method in nanoreactor system, Colloid Surface B 61 (2008) 132-137; DOI: 10.1016/j.colsurfb.2007.07.015.10.1016/j.colsurfb.2007.07.01517888636Search in Google Scholar

37. J. Jaiswal, S. K. Gupta and J. Kreuter, Preparation of biodegradable cyclosporine nanoparticles by high-pressure emulsification-solvent evaporation process, J. Control Release 96 (2004) 169-178; DOI: 10.1016/j.jconrel.2004.01.017.10.1016/j.jconrel.2004.01.017Search in Google Scholar

38. B. Sjostrom and B. Bergenstahl, Preparation of submicron drug particles in lecithin stabilized o/w emulsions I. Model studies of the precipitation of cholesteryl acetate, Int. J. Pharm. 88 (1992) 53-62; DOI: 10.1016/0378-5173(92)90303-J.10.1016/0378-5173(92)90303-JSearch in Google Scholar

39. K. Okuyama, M. Abdullah, I. W. Lenggoro and F. Iskandar, Preparation of functional nanostructured particles by spray drying, Adv. Powder Technol. 17 (2006) 587-611; DOI: 10.1163/156855206778917733.10.1163/156855206778917733Search in Google Scholar

40. K. Okuyama and I. W. Lenggoro, Preparation of nanoparticles via spray route, Chem. Eng. Sci. 58 (2003) 537-547; DOI: 10.1016/S0009-2509(02)00578-X.10.1016/S0009-2509(02)00578-XSearch in Google Scholar

41. P. Luo and T. G. Nieh, Synthesis of ultrafine hydroxyapatite particles by spray dry method, Mater. Sci. Eng. C 3 (1995) 75-78; DOI: 10.1016/0928-4931(95)00089-5.10.1016/0928-4931(95)00089-5Search in Google Scholar

42. C. Freitas and R. H. Müller, Spray-drying of solid lipid nanoparticles (SLNTM), Eur. J. Pharm. Biopharm. 46 (1998) 145-151; DOI: 10.1016/S0939-6411(97)00172-0.10.1016/S0939-6411(97)00172-0Search in Google Scholar

43. P. Tewa-Tange, S. Briancon and H. Fessi, Preparation of redispersible dry nanocapsules by means of spray-drying: Development and characterisation, Eur. J. Pharm. Sci. 30 (2007) 124-135; DOI: 10.1016/j.ejps.2006.10.006.10.1016/j.ejps.2006.10.006Search in Google Scholar

44. P. M. Gosselin, R. Thibert, M. Preda and J. N. McMullen, Polymorphic properties of micronized carbamazepine produced by RESS, Int. J. Pharm. 252 (2003) 225-233; DOI: 10.1016/S0378-5173(02)00649-X.10.1016/S0378-5173(02)00649-XSearch in Google Scholar

45. A. J. Thote and R. B. Gupta, Formation of nanoparticles of a hydrophilic drug using supercritical carbon dioxide and microencapsulation for sustained release, Nanomedicine 1 (2005) 85-90; DOI: 10.1016/j.nano.2004.12.001.10.1016/j.nano.2004.12.001Search in Google Scholar

46. J. Vandervoort and A. Ludwig, Preparation and evaluation of drug loaded gelatin nanoparticles for topical ophthalmic use, Eur. J. Pharm. Biopharm. 57 (2004) 251-261; DOI: 10.1016/S0939-6411(03)00187-5.10.1016/S0939-6411(03)00187-5Search in Google Scholar

47. R. Paliwal, S. Rai, B. Vaidya, K. Khatri, A. K. Goyal, N. Mishra, A. Mehta and S. P. Vyas, Effect of lipid core material on characteristics of solid lipid nanoparticles designed for oral lymphatic delivery, Nanomedicine 5 (2009) 184-191; DOI: 10.1016/j.nano.2008.08.003.10.1016/j.nano.2008.08.003Search in Google Scholar

48. C. Olbrich and R. H. Müller, Enzymatic degradation of SLN - Effect of surfactant and surfactant mixtures, Int. J. Pharm. 180 (1999) 31-39; DOI: 10.1016/S0378-5173(98)00404-9.10.1016/S0378-5173(98)00404-9Search in Google Scholar

49. C. C. Chen, T. H. Tsai, Z. R. Huang and J. Y. Fang, Effects of lipophilic emulsifiers on the oral administration of lovastatin from nanostructured lipid carriers: Physicochemical characterization and pharmacokinetics, Eur. J. Pharm. Biopharm. 74 (2010) 474-482; DOI: 10.1016/j.ejpb.2009.12.008.10.1016/j.ejpb.2009.12.008Search in Google Scholar

50. S. Y. Xie, S. L. Wang, B. K. Zhao, C. Han, M. Wang and W. Z. Zhou, Effect of PLGA as a polymeric emulsifier on preparation of hydrophilic protein-loaded solid lipid nanoparticles, Colloid Surface B 67 (2008) 199-204; DOI: 10.1016/j.colsurfb.2008.08.018.10.1016/j.colsurfb.2008.08.018Search in Google Scholar

51. R. Cavalli, O. Caputo, M. E. Carlotti, M. Trotta, C. Scarnecchia and M. R. Gasco, Sterilization and freeze-drying of drug-free and drug-loaded solid lipid nanoparticles, Int. J. Pharm. 148 (1997) 47-54; DOI: 10.1016/S0378-5173(96)04822-3.10.1016/S0378-5173(96)04822-3Search in Google Scholar

52. C. Schwarz, W. Mehnert, J. S. Lucks and R. H. Müller, Solid lipid nanoparticles (SLN) for controlled drug delivery. I. Production, characterisation and sterilization, J. Control Release 30 (1994) 83-96.10.1016/0168-3659(94)90047-7Search in Google Scholar

53. W. Abdelwahed, G. Degobert, S. Stainmesse and H. Fessi, Freeze-drying of nanoparticles: Formulation, process and storage considerations, Adv. Drug Del. Rev. 58 (2006) 1688-1713; DOI: 10.1016/j.addr.2006.09.017.10.1016/j.addr.2006.09.017Search in Google Scholar

54. S. D. Allison, Md. C. Molina and T. J. Anchordoquy, Stabilization of lipid/DNA complexes during the freezing step of the lyophilization process: the particle isolation hypothesis, Biochim. Biophys. Acta. 1468 (2000) 127-138; DOI: 10.1016/S0005-2736(00)00251-0.10.1016/S0005-2736(00)00251-0Search in Google Scholar

55. J. H. Crowe, J. F. Carpenter and L. M. Crowe, The role of vitrification in anhydrobiosis, Annu. Rev. Physiol. 60 (1998) 73-103; DOI: 10.1146/annurev.physiol.60.1.73.10.1146/annurev.physiol.60.1.73Search in Google Scholar

56. K. Westesen, B. Siekmann and M. H. J. Koch, Investigations on the physical state of lipid nanoparticles by synchrotron radiation X-ray diffraction, Int. J. Pharm. 93 (1993) 189-199; DOI: 10.1016/0378-5173(93)90177-H.10.1016/0378-5173(93)90177-HSearch in Google Scholar

57. H. Bunjes, K. Westesen and M. H. J. Koch, Crystallization tendencies and polymorphic transitions in triglyceride nanoparticles, Int. J. Pharm. 129 (1996) 159-173; DOI: 10.1016/0378-5173(95)04286-5.10.1016/0378-5173(95)04286-5Search in Google Scholar

58. A. Z. Muhlen, C. Schwarz and W. Mehnert, Solid lipid nanoparticles (SLN) for controlled drug delivery - Drug release and release mechanism, Eur. J. Pharm. Biopharm. 45 (1998) 149-155.10.1016/S0939-6411(97)00150-1Search in Google Scholar

59. S. Chakraborty, D. Shukla, B. Mishra and S. Singh, Lipid - An emerging platform for oral delivery of drugs with poor bioavailability, Eur. J. Pharm. Biopharm. 73 (2009) 1-15; DOI: 10.1016/j.ejpb.2009.06.001.10.1016/j.ejpb.2009.06.001Search in Google Scholar

60. A. Radomska-Soukharev, Stability of lipid excipients in solid lipid nanoparticles, Adv. Drug Del. Rev. 59 (2007) 411-418; DOI: 10.1016/j.addr.2007.04.004.10.1016/j.addr.2007.04.004Search in Google Scholar

61. B. Heurtault, P. Saulnier, B. Pech, J.-E. Proust and J. P. Benoit, Physico-chemical stability of colloidal lipid particles, Biomaterials 24 (2003) 4283-4300; DOI: 10.1016/S0142-9612(03)00331-4.10.1016/S0142-9612(03)00331-4Search in Google Scholar

62. B. Siekmann and K. Westesen, Thermoanalysis of recrystallization process of melt homogenised glyceride nanoparticles, Colloid Surface B 3 (1994) 159-175.10.1016/0927-7765(94)80063-4Search in Google Scholar

63. C. Freitas and R. H. Müller, Effect of light and temperature on zeta potential and physical stability of solid lipid nanoparticle (SLNTM) dispersions, Int. J. Pharm. 168 (1998) 221-229.10.1016/S0378-5173(98)00092-1Search in Google Scholar

64. C. Freitas and R. H. Müller, Stability determination of solid lipid nanoparticles (SLN) in aqueous dispersion after addition of electrolyte, J. Microencapsul. 16 (1999) 59-71; DOI: 10.1080/026520499289310.10.1080/026520499289310Search in Google Scholar

65. C. Freitas and R. H. Müller, Correlation between long term stability of solid lipid nanoparticles (SLNTM) and crystallinity of lipid phase, Eur. J. Pharm. Biopharm. 47 (1999) 125-132.10.1016/S0939-6411(98)00074-5Search in Google Scholar

66. K. Westesen and B. Siekmann, Investigation of the gel formation of phospholipid-stabilized solid lipid nanoparticles, Int. J. Pharm. 151 (1997) 35-45; DOI: 10.1016/S0378-5173(97)04890-4.10.1016/S0378-5173(97)04890-4Search in Google Scholar

67. R. H. Müller and S. Heinemann, Fat emulsions for parenteral nutrition. III. Lipofundin MCT/LCT regimens for total parenteral nutrition (TPN) with low electrolyte load, Int. J. Pharm. 101 (1994) 175-189; DOI: 10.1016/0378-5173(94)90213-5.10.1016/0378-5173(94)90213-5Search in Google Scholar

68. C. Freitas, J. Lucks and R. H. Müller, Effect of storage conditions on long-term stability of »solid lipid nanoparticles« (SLN) in aqueous dispersion, Eur. J. Pharm. Sci. 2 (1994) 117-194; DOI: 10.1016/0928-0987(94)90411-1.10.1016/0928-0987(94)90411-1Search in Google Scholar

69. B. Borgstrom, Importance of phospholipids, pancreatic phospholipase A2, and fatty acid for the digestion of dietary fat: in vitro experiments with the porcine enzymes, Gastroenterology 78 (1980) 954-962.Search in Google Scholar

70. R. O. Scow and T. Olivecrona, Effect of albumin on products formed from chylomicron triacylglycerol by lipoprotein lipase in vitro, Biochim. Biophys. Acta. 487 (1977) 472-486; DOI: 10.1016/0005-2760(77)90217-X.10.1016/0005-2760(77)90217-XSearch in Google Scholar

71. R. Pandey, S. Sharma and G. K. Khuller, Oral solid lipid nanoparticle-based antitubercular chemotherapy, Tuberculosis 85 (2005) 415-420, DOI: 10.1016/j.tube.2005.08.009.10.1016/j.tube.2005.08.009Search in Google Scholar

72. N. Zhang, Q. Ping, G. Huang, W. Xua, Y. Cheng and X. Han, Lectin-modified solid lipid nanoparticles as carriers for oral administration of insulin, Int. J. Pharm. 327 (2006) 153-159; DOI: 10.1016/j.ijpharm.2006.07.026.10.1016/j.ijpharm.2006.07.026Search in Google Scholar

73. M. D. Joshi and R. H. Müller, Lipid nanoparticles for parenteral delivery of actives, Eur. J. Pharm. Biopharm. 71 (2009) 161-172; DOI: 10.1016/j.ejpb.2008.09.003.10.1016/j.ejpb.2008.09.003Search in Google Scholar

74. S. A. Wissing, O. Kayser and R. H. Müller, Solid lipid nanoparticles for parenteral drug delivery, Adv. Drug Del. Rev. 56 (2004) 1257-1272; DOI: 10.1016/j.addr.2003.12.002.10.1016/j.addr.2003.12.002Search in Google Scholar

75. A. Fundarò, O, R. Cavalli, A. Bargoni, D. Vighetto, G. P. Zara and M. R. Gasco, Non-stealth and stealth solid lipid nanoparticles (SLN) carrying doxorubicin: pharmacokinetics and tissue Distribution after i.v. administration to rats, Pharmacol. Res. 42 (2000) 337-343; DOI: 10.1006/phrs.2000.0695.10.1006/phrs.2000.0695Search in Google Scholar

76. S. C. Yang, L. F. Lu, Y. Cai, J. B. Zhu, B. W. Liang and C. Z. Yanga, Body distribution in mice of intravenously injected camptothecin solid lipid nanoparticles and targeting effect on brain, J. Control. Release 59 (1999) 299-307; DOI: 10.1016/S0168-3659(99)00007-3.10.1016/S0168-3659(99)00007-3Search in Google Scholar

77. L. H. Reddy, R. K. Sharma, K. Chuttani, A. K. Mishra and R. S. R. Murthy, Influence of administration route on tumor uptake and biodistribution of etoposide loaded solid lipid nanoparticles in Dalton’s lymphoma tumor bearing mice, J. Control. Release 105 (2005) 185-198; DOI: 10.1016/j.jconrel.2005.02.028.10.1016/j.jconrel.2005.02.02815921775Search in Google Scholar

78. M. Schafer-Korting, W. Mehnert and H. C. Korting, Lipid nanoparticles for improved topical application of drugs for skin diseases, Adv. Drug Del. Rev. 59 (2007) 427-443; DOI: 10.1016/j.addr.2007.04.006.10.1016/j.addr.2007.04.006Search in Google Scholar

79. V. Jenning, M. Schafer-Korting and S. Gohla, Vitamin A-loaded solid lipid nanoparticles for topical use: drug release properties, J. Control. Release 66 (2000) 115-126; DOI: 10.1016/S0168-3659(99)00007-3.10.1016/S0168-3659(99)00007-3Search in Google Scholar

80. P. V. Pople and K. K. Singh, Development and evaluation of topical formulation containing solid lipid nanoparticles of vitamin A, AAPS PharmSciTech. 4 (2006) E1-E7; DOI: 10.1208/pt070491.10.1208/pt070491275032817285742Search in Google Scholar

81. S. K. Jain, M. K. Chourasia, R. Masuriha, V. Soni, A. Jain, Nitin K. Jain and Y. Gupta, Solid lipid nanoparticles bearing flurbiprofen for transdermal delivery, Drug Del. 12 (2005) 207-215; DOI: 10.1080/10717540590952591.10.1080/1071754059095259116036715Search in Google Scholar

82. A. J. Almeida and E. Souto, Solid lipid nanoparticles as a drug delivery system for peptides and proteins, Ad.v Drug Del. Rev. 59 (2007) 478-490; DOI: 10.1016/j.addr.2007.04.007.10.1016/j.addr.2007.04.00717543416Search in Google Scholar

83. J. Liu, T. Gong, H. Fu, C. Wang, X. Wang, Q. Chena, Q. Zhang, Q. Hea and Z. Zhang, Solid lipid nanoparticles for pulmonary delivery of insulin, Int. J. Pharm. 356 (2008) 333-344; DOI: 10.1016/j.ijpharm.2008.01.008.10.1016/j.ijpharm.2008.01.00818281169Search in Google Scholar

84. J. Araujo, E. Gonzalez, M. A. Egea, M. L. Garcia and E. B. Souto, Nanomedicines for ocular NSAIDs: safety on drug delivery, Nanomedicine 5 (2009) 394-401; DOI: 10.1016/j.nano.2009.02.003.10.1016/j.nano.2009.02.00319341814Search in Google Scholar

85. M. I. Alam, S. Beg, A. Samad, S. Baboota, K. Kohli, J. Ali, A. Ahuja and M. Akbar, Strategy for effective brain drug delivery, Eur. J. Pharm. Sci. 40 (2010) 385-403; DOI: 10.1016/j.ejps.2010.05.003.10.1016/j.ejps.2010.05.00320497904Search in Google Scholar

86. I. P. Kaur, R. Bhandari, S. Bhandari and V. Kakkar, Potential of solid lipid nanoparticles in brain targeting, J. Control. Release 127 (2008) 97-100; DOI: 10.1016/j.jconrel.2007.12.018.10.1016/j.jconrel.2007.12.01818313785Search in Google Scholar

87. A. Mistry, S. Stolnik and L. Illum, Nanoparticles for direct nose-to-brain delivery of drugs, Int. J. Pharm. 379 (2009) 146-157; DOI: 10.1016/j.ijpharm.2009.06.019.10.1016/j.ijpharm.2009.06.01919555750Search in Google Scholar

88. I. Brasnjevic, H. W. M. Steinbusch, C. Schmitz and P. Martinez-Martinez, Delivery of peptide and protein drugs over the blood-brain barrier, Prog. Neurobiol. 87 (2009) 212-251; DOI: 10.1016/j.pneurobio.2008.12.002.10.1016/j.pneurobio.2008.12.002Search in Google Scholar

89. F. Chellat, Y. Merhi, A. Moreau and L. H. Yahia, Therapeutic potential of nanoparticulate systems for macrophage targeting, Biomaterials 26 (2005) 7260-7275; DOI: 10.1016/j.biomaterials.2005.05.044.10.1016/j.biomaterials.2005.05.044Search in Google Scholar

90. H. Chen, X. Chang, D. Du, W. Liu, J. Liu, T. Weng, Y. Yang, H. Xu and X. Yang, Podophyllotoxin-loaded solid lipid nanoparticles for epidermal targeting, J. Control. Release 110 (2006) 296-306; DOI: 10.1016/j.jconrel.2005.09.052.10.1016/j.jconrel.2005.09.052Search in Google Scholar

91. R. H. Müller, S. Maaben, H. Weyhers, F. Specht and J. S. Lucks, Cytotoxicity of magnetite-loaded polylactide, polylactide/glycolide particles and solid lipid nanoparticles, Int. J. Pharm. 138 (1996) 85-94; DOI: 10.1016/0378-5173(96)04539-5.10.1016/0378-5173(96)04539-5Search in Google Scholar

92. D. M. Radolfi, P. D. Marcato, R. A. Silva, G. Z. Justo and N. Duran, In vitro cytotoxicity assay of solid lipid nanoparticles in epithelial and dermal cells, J. Phys. Conf. Ser. 304 (2011) 1-4; DOI: 10.1088/1742-6596/304/1/012032.10.1088/1742-6596/304/1/012032Search in Google Scholar

93. H. Yuan, J. Miao, Y. Z. Du, J. You, F. Q. Hu and S. Zeng, Cellular uptake of solid lipid nanoparticles and cytotoxicity of encapsulated paclitaxel in A549 cancer cells, Int. J. Pharm. 348 (2008) 137-145; DOI: 10.1016/j.ijpharm.2007.07.012.10.1016/j.ijpharm.2007.07.01217714896Search in Google Scholar

94. J. C. Olivier, Drug transport to brain with targeted nanoparticles, NeuroRx. 1 ( 2005) 108-119; DOI: 10.1602/neurorx.2.1.108.10.1602/neurorx.2.1.10853932915717062Search in Google Scholar

95. T. R. Pisanic II, J. D. Blackwell, V. I. Shubayev, R. R. Fiñones and S. Jin, Nanotoxicity of iron oxide nanoparticle internalization in growing neurons, Biomaterials 28 (2007) 2572-2581; DOI: 10.1016/j.biomaterials.2007.01.043.10.1016/j.biomaterials.2007.01.04317320946Search in Google Scholar

96. H. C. Fischer, W. C. Chan, Nanotoxicity: the growing need for in vivo study, Curr. Opin. Biotechnol. 18 (2007) 565-571; DOI: 10.1016/j.copbio.2007.11.008.10.1016/j.copbio.2007.11.00818160274Search in Google Scholar

97. Y. L. Hu and J. Q. Gao, Potential neurotoxicity of nanoparticles, Int. J. Pharm. 394 (2010) 115-121; DOI: 10.1016/j.ijpharm.2010.04.026.10.1016/j.ijpharm.2010.04.02620433914Search in Google Scholar

98. K. Jores, W. Mehnert, M. Drechsler, H. Bunjes, C. Johann and K. Mäder, Investigations on the structure of solid lipid nanoparticles (SLN) and oil-loaded solid lipid nanoparticles by photon correlation spectroscopy, field-flow fractionation and transmission electron microscopy, J. Control. Release 95 (2004) 217-227; DOI: 10.1016/j.jconrel.2003.11.012.10.1016/j.jconrel.2003.11.012Search in Google Scholar

99. S. Chakraborty, B. Sahoo, I. Teraoka and R. A. Gross, Solution properties of starch nanoparticles in water and DMSO as studied by dynamic light scattering, Carbohydr Polym. 60 (2005) 475-481; DOI: 10.1016/j.carbpol.2005.03.011.10.1016/j.carbpol.2005.03.011Search in Google Scholar

100. B. G. Zanetti-Ramos, M. B. Fritzen-Garcia, C. S. de Oliveira, A. A. Pasa, V. Soldi, R. Borsali and T. B. Creczynski-Pasa, Dynamic light scattering and atomic force microscopy techniques for size determination of polyurethane nanoparticles, Mater. Sci. Eng. C. Mater. Biol. App. 29 (2009) 638-640; DOI: 10.1016/j.msec.2008.10.040.10.1016/j.msec.2008.10.040Search in Google Scholar

101. L. Dulog and T. Schauer, Field flow fractionation for particle size determination, Prog. Org. Coat. 28 (1996) 25-31; DOI: 10.1016/0300-9440(95)00584-6.10.1016/0300-9440(95)00584-6Search in Google Scholar

102. A. S. Dukhin, P. J. Goetz, X. Fang and P. Somasundaran, Monitoring nanoparticles in the presence of larger particles in liquids using acoustics and electron microscopy, J. Colloid Inter. Sci. 342 (2010) 18-25; DOI: 10.1016/j.jcis.2009.07.001.10.1016/j.jcis.2009.07.001Search in Google Scholar

103. V. Jenning, K. Mäder and S. H. Gohla, Solid lipid nanoparticles (SLN™) based on binary mixtures of liquid and solid lipids: 1H-NMR study, Int. J. Pharm. 205 (2000) 15-21; DOI: 10.1016/S0378-5173(00)00462-2.10.1016/S0378-5173(00)00462-2Search in Google Scholar

104. A. Dubes, H. Parrot-Lopez, W. Abdelwahed, G. Degobert, H. Fessi, P. Shahgaldian and A. W. Coleman, Scanning electron microscopy and atomic force microscopy imaging of solid lipid nanoparticles derived from amphiphilic cyclodextrins, Eur. J. Pharm. Biopharm. 55 (2003) 279-282; DOI: 10.1016/S0939-6411(03)00020-1.10.1016/S0939-6411(03)00020-1Search in Google Scholar

105. M. Albrecht, V. Janke, S. Sievers, U. Siegner, D. Schulerb and U. Heyen, Scanning force microscopy study of biogenic nanoparticles for medical applications, J. Magn. Magn. Mater. 290-291 (2005) 269-271; DOI: 10.1016/j.jmmm.2004.11.206.10.1016/j.jmmm.2004.11.206Search in Google Scholar

106. N. Škalko, J. Bouwstra, F. Spies, M. Stuart, P. M. Frederik and G. Gregoriadis, Morphological observations on liposomes bearing covalently bound protein: Studies with freeze-fracture and cryo electron microscopy and small angle X-ray scattering techniques, Biochim. Biophys. Acta 1370 (1998) 151-160; DOI: 10.1016/S0005-2736(97)00256-3.10.1016/S0005-2736(97)00256-3Search in Google Scholar

107. K. Fowler, L. A. Bottomley and H. Schreier, Surface topography of phospholipid bilayer and vesicles (liposomes) by scanning tunnelling microscopy (STM), J. Control. Release 22 (1992) 283-292; DOI: 10.1016/0168-3659(92)90103-X.10.1016/0168-3659(92)90103-XSearch in Google Scholar

108. O. Robach, C. Quiros, S. M. Valvidares, C. J. Walker and S. Ferrer, Structure and Pt magnetism of FePt nanoparticles investigated with X-ray diffraction, J. Magn. Magn. Mater. 264 (2003) 202-208; DOI: 10.1016/S0304-8853(03)00205-1.10.1016/S0304-8853(03)00205-1Search in Google Scholar

109. M. A. Schubert, B. C. Schicke and C. C. Muller-Goymann, Thermal analysis of the crystallization and melting behaviour of lipid matrices and lipid nanoparticles containing high amounts of lecithin, Int. J. Pharm. 298 (2005) 242-254; DOI: 10.1016/j.ijpharm.2005.04.014.10.1016/j.ijpharm.2005.04.014Search in Google Scholar

110. S. A. Wissing and R. H. Müller, Solid lipid nanoparticles as carrier for sunscreens: in vitro release and in vivo skin penetration, J. Control. Release 81 (2002) 225-233; DOI: 10.1016/S0168-3659(02)00056-1.10.1016/S0168-3659(02)00056-1Search in Google Scholar

111. C. Song and S. Liu, A new healthy sunscreen system for human: Solid lipid nannoparticles as carrier for 3,4,5-trimethoxybenzoylchitin and the improvement by adding vitamin E, Int. J. Biol. Macromol. 36 (2005) 116-119; DOI: 10.1016/j.ijbiomac.2005.05.003.10.1016/j.ijbiomac.2005.05.003Search in Google Scholar

112. J. Pardeike, A. Hommoss and R. H. Müller, Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products, Int. J. Pharm. 366 (2009) 170-184; DOI: 10.1016/j.ijpharm.2008.10.003.10.1016/j.ijpharm.2008.10.003Search in Google Scholar

113. S. A. Wissing and R. H. Müller, Cosmetic applications for solid lipid nanoparticles (SLN), Int. J. Pharm. 254 (2003) 65-68; DOI: 10.1016/S0378-5173(02)00684-1.10.1016/S0378-5173(02)00684-1Search in Google Scholar

114. K. A. Shah, A. A. Date, M. D. Joshi and V. B. Patravale, Solid lipid nanoparticles (SLN) of tretinoin: Potential in topical delivery, Int. J. Pharm. 345 (2007) 163-171; DOI: 10.1016/j.ijpharm.2007.05.061.10.1016/j.ijpharm.2007.05.06117644288Search in Google Scholar

115. J. Liu, W. Hu, H. Chen, Q. Ni, H. Xu and X. Yang, Isotretinoin-loaded solid lipid nanoparticles with skin targeting for topical delivery, Int. J. Pharm. 328 (2007) 191-195; DOI: 10.1016/j.ijpharm.2006.08.007.10.1016/j.ijpharm.2006.08.00716978810Search in Google Scholar

116. M. S. Korting, W. Mehnert and H. C. Korting, Lipid nanoparticles for improved topical application of drugs for skin diseases, Adv. Drug Del. Rev. 59 (2007) 427-443; DOI: 10.1016/j.addr.2007.04.006.10.1016/j.addr.2007.04.00617544165Search in Google Scholar

117. A. del Pozo-Rodrigueza, D. Delgadoa, M. A. Solinis, J. L. Pedraza, E. Echevarria, J. M. Rodriguez and A. R. Gascona, Solid lipid nanoparticles as potential tools for gene therapy: In vivo protein expression after intravenous administration, Int. J. Pharm. 385 (2010) 157-162; DOI: 10.1016/j.ijpharm.2009.10.020.10.1016/j.ijpharm.2009.10.02019835940Search in Google Scholar

118. S. H. Choi, S. E. Jin, M. K. Lee, S. J. Lim, J. S. Park, B. G. Kim, W. S. Ahn and C. K. Kim, Novel cationic solid lipid nanoparticles enhanced p53 gene transfer to lung cancer cells, Eur. J. Pharm. Biopharm. 68 (2008) 545-554; DOI: 10.1016/j.ejpb.2007.07.011.10.1016/j.ejpb.2007.07.011Search in Google Scholar

119. N. Pedersen, S. Hansen, A. V. Heydenreich, H. G. Kristensen and H. S. Poulsen, Solid lipid nanoparticles can effectively bind DNA, streptavidin and biotinylated ligands, Eur. J. Pharm. Biopharm. 62 (2006) 155-162; DOI: 10.1016/j.ejpb.2005.09.003.10.1016/j.ejpb.2005.09.003Search in Google Scholar

120. H. L. Wong, R. Bendayan, A. M. Rauth, Y. Li and X. Y. Wu, Chemotherapy with anticancer drugs encapsulated in solid lipid nanoparticles, Adv. Drug Del. Rev. 59 (2007) 491-504; DOI: 10.1016/j.addr.2007.04.008.10.1016/j.addr.2007.04.008Search in Google Scholar

121. H. L. Wong, R. Bendayan, A. M. Rauth and X. Y. Wu, Simultaneous delivery of doxorubicin and GG918 (Elacridar) by new Polymer-Lipid Hybrid Nanoparticles (PLN) for enhanced treatment of multidrug-resistant breast cancer, J. Control. Release 116 (2006) 275-284; DOI: 10.1016/j.jconrel.2006.09.007.10.1016/j.jconrel.2006.09.007Search in Google Scholar

122. R. K. Subedi, K. W. Kang and H. K. Choi, Preparation and characterization of solid lipid nanoparticles loaded with doxorubicin, Eur. J. Pharm. Sci. 37 (2009) 508-513; DOI: 10.1016/j.ejps.2009.04.008.10.1016/j.ejps.2009.04.008Search in Google Scholar

123. B. Lu, S. B. Xiong, H. Yang, X. D. Yin and R. B. Chao, Solid lipid nanoparticles of mitoxantrone for local injection against breast cancer and its lymph node metastases, Eur. J. Pharm. Sci. 28 (2006) 86-95; DOI: 10.1016/j.ejps.2006.01.001.10.1016/j.ejps.2006.01.001Search in Google Scholar

124. N. Csaba, M. Garcia-Fuentes and M. J. Alonso, Nanoparticles for nasal vaccination, Adv. Drug Del. Rev. 61 (2009) 140-157; DOI: 10.1016/j.addr.2008.09.005.10.1016/j.addr.2008.09.005Search in Google Scholar

125. S. M. Moghimi and J. Szebeni, Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties, Prog. Lipid Res. 42 (2003) 463-478; DOI: 10.1016/S0163-7827(03)00033-X.10.1016/S0163-7827(03)00033-XSearch in Google Scholar

126. Y. Wang and W. Wu, In situ evading of phagocytic uptake of stealth solid lipid nanoparticles by mouse peritoneal macrophages, Drug Deliv. 3 (2006) 189-192; DOI: 10.1080/10717540-500-315330.Search in Google Scholar

127. M. R. Gasco, Lipid nanoparticles: perspectives and challenges, Adv. Drug Del. Rev. 59 (2007) 377-378; DOI: 10.1016/j.addr.2007.05.004.10.1016/j.addr.2007.05.004Search in Google Scholar

128. A. J. Domb, Long acting injectable oxytetracycline-liposphere formulations, Int. J. Pharm. 124 (1995) 271-278; DOI: 10.1016/0378-5173(95)00098-4.10.1016/0378-5173(95)00098-4Search in Google Scholar

129. C. Schwarz and W. Mehnert, Freeze-drying of drug-free and drug-loaded solid lipid nanoparticles (SLN), Int. J. Pharm. 157 (1997) 171-179; DOI: 10.1016/S0378-5173(97)00222-6.10.1016/S0378-5173(97)00222-6Search in Google Scholar

130. K. Westesen, H. Bunjes and M. H. J. Koch, Physicochemical characterization of lipid nanoparticles and evaluation of their drug loading capacity and sustained release potential, J. Control. Release 48 (1997) 223-236; DOI: 10.1016/S0168-3659(97)00046-1.10.1016/S0168-3659(97)00046-1Search in Google Scholar

131. K. Westesen, B. Siekmann and M. H. J. Koch, Investigations on the physical state of lipid nanoparticles by synchrotron radiation X-ray diffraction, Int. J. Pharm. 93 (1993) 189-199; DOI: 10.1016/0378-5173(93)90177-H.10.1016/0378-5173(93)90177-HSearch in Google Scholar

132. A. J. Almeida, S. Runge and R. H. Müller, Peptide-loaded solid lipid nanoparticles (SLN): influence of production parameters, Int. J. Pharm. 149 (1997) 255-265; DOI: 10.1016/S0378-5173(97)04885-0.10.1016/S0378-5173(97)04885-0Search in Google Scholar

133. R. Cavalli, E. Peira, O. Caputo and M. R. Gasco, Solid lipid nanoparticles as carriers of hydrocortisone and progesterone complexes with a-cyclodextrins, Int. J. Pharm. 182 (1999) 59-69.10.1016/S0378-5173(99)00066-6Search in Google Scholar

134. H. Ali, A. B. Shirode, P. W. Sylvester and S. Nazzal, Preparation and in vitro antiproliferative effect of tocotrienol loaded lipid nanoparticles, Colloid Surface A 353 (2010) 43-51; DOI: 10.1016/j.colsurfa.2009.10.020.10.1016/j.colsurfa.2009.10.020Search in Google Scholar

135. R. Cavalli, S. Morel, M. R. Gasco, P. Chetoni and M. F. Saettone, Preparation and evaluation in vitro of colloidal lipospheres containing pilocarpine as ion pair, Int. J. Pharm. 117 (1995) 243-246; DOI: 10.1016/0378-5173(94)00339-7.10.1016/0378-5173(94)00339-7Search in Google Scholar

136. S. Morel, E. Terreno, E. Ugazio, S. Aime and M. R. Gasco, NMR relaxometric investigations of solid lipid nanoparticles (SLN) containing gadolinium(III) complexes, Eur. J. Pharm. Biopharm. 45 (1998) 157-163; DOI: 10.1016/S0939-6411(97)00107-0.10.1016/S0939-6411(97)00107-0Search in Google Scholar

137. M. R. Gasco, R. Cavalli and M. E. Carlotti, Timolol in lipospheres, Pharmazie 47 (1992) 119-121.Search in Google Scholar

138. A. A. Attama and C. C. Müller-Goymann, Effect of beeswax modification on the lipid matrix and solid lipid nanoparticle crystallinity, Colloid Surface A 315 (2008) 189-195; DOI: 10.1016/j.colsurfa.2007.07.035.10.1016/j.colsurfa.2007.07.035Search in Google Scholar

139. S. Kheradmandia, E. Vasheghani-Farahani, M. Nosrati and F. Atyabi, Preparation and characterization of ketoprofen-loaded solid lipid nanoparticles made from beeswax and carnauba wax, Nanomedicine 6 (2010) 753-759; DOI: 10.1016/j.nano.2010.06.003.10.1016/j.nano.2010.06.00320599527Search in Google Scholar

140. B. D. Kim, K. Na and H. K. Choi, Preparation and characterization of solid lipid nanoparticles (SLN) made of cacao butter and curdlan, Eur. J. Pharm. Sci. 24 (2005) 199-205; DOI: 10.1016/j.ejps.2004.10.008.10.1016/j.ejps.2004.10.008Search in Google Scholar

141. C. Bocca, O. Caputo, R. Cavalli, L. Gabrial, A. Miglietta and M. R. Gasco, Phagocytic uptake of fluorescent stealth and non-stealth solid lipid nanoparticles, Int. J. Pharm. 175 (1998) 185-193; DOI: 10.1016/S0378-5173(98)00282-8.10.1016/S0378-5173(98)00282-8Search in Google Scholar

142. T. M. Goppert and R. H. Müller, Protein adsorption patterns on poloxamer- and poloxamine-stabilized solid lipid nanoparticles (SLN), Eur. J. Pharm. Biopharm. 60 (2005) 361-372; DOI: 10.1016/j.ejpb.2005.02.006.10.1016/j.ejpb.2005.02.006Search in Google Scholar

143. H. M. Redhead, S. S. Davis and L. Illum, Drug delivery in poly(lactide-co-glycolide) nanoparticles surface modified with poloxamer 407 and poloxamine 908: in vitro characterisation and in vivo evaluation, J. Control. Release 70 (2001) 353-363.Search in Google Scholar

144. C. Olbrich, O. Kayser and R. H. Müller, Lipase degradation of Dynasan 114 and 116 solid lipid nanoparticles (SLN) - effect of surfactants, storage time and crystallinity, Int. J. Pharm. 237 (2002) 119-128; DOI: 10.1016/S0378-5173(02)00035-2.10.1016/S0378-5173(02)00035-2Search in Google Scholar

145. C. C. Shen, W. L. Tseng and M. M. Hsieh, Selective enrichment of aminothiols using polysorbate 20-capped gold nanoparticles followed by capillary electrophoresis with laser-induced fluorescence, J. Chromatogr. A 1216 (2009) 288-293; DOI: 10.1016/j.chroma.2008.11.044.10.1016/j.chroma.2008.11.044Search in Google Scholar

146. L. D. Marzio, C. Marianecci, M. Petrone, F. Renaldi and M. Carafa, Novel pH-sensitive non-ionic surfactant vesicles: comparison between Tween 21 and Tween 20, Colloid Surface B 82 (2011) 18-24; DOI: 10.1016/j.colsurfb.2010.08.004.10.1016/j.colsurfb.2010.08.004Search in Google Scholar

147. L. H. Reddy, K. Vivek, N. Bakshi and R. S. R. Murthy, Tamoxifen citrate loaded solid lipid nanoparticles (SLN™): Preparation, characterization, in vitro drug release, and pharmacokinetic evaluation, Pharm. Dev. Technol. 11 (2006) 167-177; 2006, DOI: 10.1080/10837450600561265.10.1080/10837450600561265Search in Google Scholar

148. F. Q. Hu, H. Yuan, H. H. Zhang and M. Fang, Preparation of solid lipid nanoparticles with clobetasol propionate by a novel solvent diffusion method in aqueous system and physicochemical characterization, Int. J. Pharm. 239 (2002) 121-128; DOI: 10.1016/S0378-5173(02)00081-9. 10.1016/S0378-5173(02)00081-9Search in Google Scholar

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