Open Access

Simple RP-HPLC method for determination of triple drug combination of valsartan, amlodipine and hydrochlorothiazide in human plasma


Cite

N. Koseki, H. Kawashita, H. Hara, M. Niina, M. Tanaka, R. Kawai, Y. Nagae and N. Masuda, Development and validation of a method for quantitative determination of valsartan in human plasma by liquid chromatography-tandem mass spectrometry, J. Pharm. Biomed. Anal. 43 (2007) 1769-1774; DOI: 10.1016/j.jpba.2006.12.030.10.1016/j.jpba.2006.12.030Search in Google Scholar

M. Doménech and A. Coca, Role of triple fixed combination valsartan, amlodipine and hydrochlorothiazide in controlling blood pressure, Patient Pref. Adh. 4 (2010) 105-113.Search in Google Scholar

The Merck Index (Ed. S. Budavari), 13th ed. Merck & Co. Inc., Whitehouse Station (NJ) 2001.Search in Google Scholar

N. Daneshtalab, R. Z. Lewanczuk and F. Jamali, High-performance liquid chromatographic analysis of angiotensin II receptor antagonist valsartan using a liquid extraction method, J. Chromatogr. B. 766 (2002) 345-349; DOI: 10.1016/S0378-4347(01)00507-2.10.1016/S0378-4347(01)00507-2Search in Google Scholar

E. K. Schmidt, K. H. Antonin, G. Flesch and A. Racine-Poon, An interaction study with cimetidine and the new angiotensin II antagonist valsartan, Eur. J. Clin. Pharmacol. 53 (1998) 451-458; DOI: 10.1007/s002280050406.10.1007/s0022800504069551704Search in Google Scholar

F. Waldmeier, G. Flesch, P. Muller, T. Winkler, H. P. Kriemler, P. Buhlmayer and M. De Gasparo, Pharmacokinetics, disposition and biotransformation of [14C]-radiolabelled valsartan in healthy male volunteers after a single oral dose, Xenobiotica 27 (1997) 59-71; DOI: 10.1080/004982597240767.10.1080/0049825972407679041679Search in Google Scholar

P. Pickkers, A. D. Hughes, F. G. M. Russel, T. Thien and P. Smits, Thiazide-induced vasodilation in humans is mediated by potassium channel activation, Hypertension 32 (1998) 1071-1076.10.1161/01.HYP.32.6.10719856976Search in Google Scholar

S. G. Chrysant, Fixed low-dose drug combination for the treatment of hypertension, Arch. Fam. Med. 7 (1998) 370-376; DOI: 10.1001/archfami.7.4.370.10.1001/archfami.7.4.3709682692Search in Google Scholar

J. Macek, J. Klima and P. Ptácek, Rapid determination of valsartan in human plasma by protein precipitation and high-performance liquid chromatography, J. Chromatogr. B 832 (2006) 169-172; DOI: 10.1016/j.jchromb.2005.12.035.10.1016/j.jchromb.2005.12.03516426905Search in Google Scholar

B. Koçyiğit-Kaymakçoğlu, S. Unsalan and S. Rollas, Determination and validation of ketoprofen, pantoprazole and valsartan together in human plasma by high performance liquid chromatography, Pharmazie 61 (2006) 586-589.Search in Google Scholar

Zarghi, S. M. Foroutan, A. Shafaati and A. Khoddam, Validated HPLC method for determination of amlodipine in human plasma and its application to pharmacokinetic studies, Farmaco 60 (2005) 789-792; DOI: 10.1016/j.farmac.2005.06.012.10.1016/j.farmac.2005.06.01216038908Search in Google Scholar

R. V. S. Nirogi, V. N. Kandikere, K. Mudigonda, M. Shukla and S. Maurya, Sensitive and rapid liquid chromatography/tandem mass spectrometry assay for the quantification of amlodipine in human plasma, Biomed. Chromatogr. 20 (2006) 833-842; DOI: 10.1002/bmc.600.10.1002/bmc.60016397912Search in Google Scholar

L. Li, J. Sun, P. Yang and Z. He, Liquid chromatography-electrospray ionization mass spectrometric method for the determination of hydrochlorothiazide in human plasma: application to a pharmacokinetic study, Anal. Lett. 39 (2006) 2797-2807; DOI: 10.1080/00032710600867465.10.1080/00032710600867465Search in Google Scholar

H. Li, Y. Wang, Y. Jiang, Y. Tang, J. Wang, L. Zhao and J. Gu, A liquid chromatography/tandem mass spectrometry method for the simultaneous quantification of valsartan and hydrochlorothiazide in human plasma, J. Chromatog. B 852 (2007) 436-442; DOI: 10.1016/j.jchromb.2007.02.014.10.1016/j.jchromb.2007.02.01417331816Search in Google Scholar

M. Çelebier, M. S. Kaynak, S. Altınöz and S. Şahin, Validated HPLC method development: the simultaneous analysis of amlodipine and valsartan in samples for liver perfusion studies, Hacettepe Univ. J. Fac. Phar. 28 (2008) 15-30.Search in Google Scholar

FDA, Guidance for Industry, Bioanalytical Method Validation, U.S. Department of Health and Human Services, FDA, CDER and CVM, Rockville 2001.Search in Google Scholar

EMEA, Draft Guidelines on Validation of Bioanalytical Methods, Committee for Medicinal Products for Human Use, EMEA, London 2009.Search in Google Scholar

eISSN:
1846-9558
ISSN:
1330-0075
Language:
English
Publication timeframe:
4 times per year
Journal Subjects:
Pharmacy, other