<abstract xml:lang="en" xmlns="http://www.w3.org/1999/xhtml"><p>A water for injection system supplies chilled sterile water as a solvent for pharmaceutical products. There are ultimate requirements for the quality of the sterile water, and the consequence of a fault in temperature or in flow control within the process may cause a loss of one or more batches of the production. Early diagnosis of faults is hence of considerable interest for this process. This study investigates the properties of multiple matchings with respect to isolability, and it suggests to explore the topologies of multiple use-modes for the process and to employ active techniques for fault isolation to enhance structural isolability of faults. The suggested methods are validated on a high-fidelity simulation of the process.</p></abstract>

A water for injection system supplies chilled sterile water as a solvent for pharmaceutical products. There are ultimate requirements for the quality of the sterile water, and the consequence of a fault in temperature or in flow control within the process may cause a loss of one or more batches of the production. Early diagnosis of faults is hence of considerable interest for this process. This study investigates the properties of multiple matchings with respect to isolability, and it suggests to explore the topologies of multiple use-modes for the process and to employ active techniques for fault isolation to enhance structural isolability of faults. The suggested methods are validated on a high-fidelity simulation of the process.

Fault Diagnosis Of A Water For Injection System Using Enhanced Structural Isolation

Automation and Control Group, Department of Electrical Engineering, Technical University of Denmark, Elektrovej build. 326, DK 2800 Kgs. Lyngby, Denmark

Centre for Ships and Ocean Structures, Norwegian University of Science and Technology, NO 7491 Trondheim, Norway

Center for Advanced Power Systems, Florida State University, 2000 Levy Ave., Tallahassee, FL 32310, USA

International Journal of Applied Mathematics and Computer Science

A water for injection system supplies chilled sterile water as a solvent for pharmaceutical products. There are ultimate requirements for the quality of the...

Fault Diagnosis Of A Water For Injection System Using Enhanced Structural Isolation

Published Online: Dec 30, 2008

Page range: 593 - 604

DOI: https://doi.org/10.2478/v10006-008-0052-5

Keywords
structural analysis, fault isolation, fault diagnosis, matching

This content is open access.

Fault Diagnosis Of A Water For Injection System Using Enhanced Structural Isolation

Published Online: Dec 30, 2008

Page range: 593 - 604

DOI: https://doi.org/10.2478/v10006-008-0052-5

Keywordsstructural analysis, fault isolation, fault diagnosis, matching

This content is open access.

Keywords
structural analysis, fault isolation, fault diagnosis, matching