<abstract xmlns="http://www.w3.org/1999/xhtml">

Aspirin is one of the most widely used medications globally as an analgesic and antipyretic drug. Aspirin use as an antiparasitic against fish parasites has never been tested. The parasite <italic>Dactylogyrus</italic> is considered a serious threat to freshwater aquaculture in relation to considerable losses. The present study is aimed to evaluate the antiparasitic effect of aspirin against <italic>Dactylogyrus extensus</italic> on <italic>Cyprinus carpio</italic> and alteration in gill histopathology. <italic>In vitro</italic>, aspirin exhibited antiparasitic activity with median effective concentration (EC50) values at one and six minutes of 8.137 g/L−1 and 1.629 g/L−1, were assessed for the first time. <italic>In vivo</italic> antiparasitic efficacy of aspirin to <italic>D. extensus</italic> was found to be 46.49%. Severe lesion profile was observed in histopathological evaluations of the gills.
</abstract>

Aspirin is one of the most widely used medications globally as an analgesic and antipyretic drug. Aspirin use as an antiparasitic against fish parasites has never been tested. The parasite Dactylogyrus is considered a serious threat to freshwater aquaculture in relation to considerable losses. The present study is aimed to evaluate the antiparasitic effect of aspirin against Dactylogyrus extensus on Cyprinus carpio and alteration in gill histopathology. In vitro, aspirin exhibited antiparasitic activity with median effective concentration (EC50) values at one and six minutes of 8.137 g/L−1 and 1.629 g/L−1, were assessed for the first time. In vivo antiparasitic efficacy of aspirin to D. extensus was found to be 46.49%. Severe lesion profile was observed in histopathological evaluations of the gills.

<italic>In Vitro</italic> and <italic>in Vivo</italic> Studies of the Antiparasitic Effect of Aspirin Against <italic>Dactylogyrus Extensus</italic> (Monogenea) Invasion in Carp (<italic>Cyprinus carpio</italic>)

Ankara University, Faculty of Agriculture

Transylvanian Review of Systematical and Ecological Research

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

 and  Studies of the Antiparasitic Effect of Aspirin Against  (Monogenea) Invasion in Carp ()

Aspirin is one of the most widely used medications globally as an analgesic and antipyretic drug. Aspirin use as an antiparasitic against fish parasites has...

In Vitro and in Vivo Studies of the Antiparasitic Effect of Aspirin Against Dactylogyrus Extensus (Monogenea) Invasion in Carp (Cyprinus carpio)

Published Online: Jan 07, 2023

Page range: 73 - 82

DOI: https://doi.org/10.2478/trser-2022-0012

Keywords
Aspirin (ASA), antiparasitic, gill histopathology

© 2022 Faik Sertel Secer et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

In Vitro and in Vivo Studies of the Antiparasitic Effect of Aspirin Against Dactylogyrus Extensus (Monogenea) Invasion in Carp (Cyprinus carpio)

Published Online: Jan 07, 2023

Page range: 73 - 82

DOI: https://doi.org/10.2478/trser-2022-0012

KeywordsAspirin (ASA), antiparasitic, gill histopathology

© 2022 Faik Sertel Secer et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
Aspirin (ASA), antiparasitic, gill histopathology