Maternal Hypertensive disorders | 27/417 (6.5) | 25/430 (5.8) | 1.12 [0.64–1.97] | N/A |
Excessive GWG | 130/403 (32.3) | 118/410 (28.8) | 1.18 [0.87–1.59] | 1.16 [0.85–1.58] |
Caesarean section | 98/411 (23.8) | 100/417 (24.0) | 0.99 [0.72–1.37] | 0.99 [0.71–1.39] |
Induction of labour | 130/412 (31.6) | 142/419 (33.9) | 0.90 [0.67–1.20] | 0.89 [0.66–1.20] |
Perinatal | ||||
LGA | 58/398 (14.6) | 49/419 (11.7) | 1.29 [0.86–1.94] | 1.24 [0.81–1.90] |
SGA | 17/398 (4.3) | 26/419 (6.2) | 0.67 [0.236–1.26] | N/A |
Preterm birth (<37 weeks) | 34/399 (8.5) | 33/419 (7.9) | 1.09 [0.66–1.80] | 1.04 [0.62–1.74] |
Hypoglycaemia | 7/412 (1.7) | 16/418 (3.8) | 0.43 [0.18–1.07] | N/A |
Hyperbilirubinemia | 55/413 (13.3) | 56/418 (13.4) | 0.99 [0.67–1.48] | 0.96 [0.63–1.45] |
Child composite adverse outcomea | 61/410 (14.9) | 72/418 (17.2) | 0.84 [0.58–1.22] | 0.80 [0.54–1.17] |
Number |
N=417 |
N=430 |
N=178 |
N=190 |
Fasting glucose/ | 5.2** | 5.1 | 5.3** | 5.2 |
0 min OGTT, mmol/l |
[5.0–5.4] |
[4.8–5.3] |
[5.1–5.5] |
[5.0–5.3] |
60 min OGTT, mmol/l | 10.1 | 9.9 | 10.1 | 10.1 |
|
[9.1–10.7] |
[9.1–10.6] |
[9.3–10.9] |
[9.0–10.6] |
120 min OGTT, mmol/l | 9.1 | 9.0 | 9.2 | 9.0 |
|
[8.6–9.7] |
[8.6–9.6] |
[8.6–9.5] |
[8.6–9.5] |
HbA1c first visit during follow-up, % | 4.9*** | 5.0 | 4.9* | 5.0 |
|
[4.8–5.1] |
[4.8–5.2] |
[4.8–5.1] |
[4.8–5.2] |
mmol/mol | 30.1 | 31.1 | 30.1 | 31.1 |
|
[29.0–32.2] |
[29.0–33.3] |
[29.0–32.2] |
[29.0–33.3] |
GA first visit | 28.0*** | 29.6 | 20.1*** | 29.0 |
during follow-up, week |
[16.4–30.0] |
[26.5–31.4] |
[14.9–28.9] |
[17.9–31.3] |
Average HbA1c between first and last visit, % | 4.9*** | 5.1 | 4.9 | 5.0 |
|
[4.8–5.2] |
[4.9–5.4] |
[4.8–5.2] |
[4.9–5.2] |
mmol/mol | 30.1 | 32.2 | 30.1 | 31.1 |
|
[29.0–33.3] |
[30.1–35.5] |
[28.4–33.3] |
[30.1–33.3] |
HbA1c last visit, % | 5.1*** | 5.2 | 5.2** | 5.3 |
|
[4.9–5.4] |
[5.0–5.4] |
[4.9–5.4] |
[5.0–5.5] |
mmol/mol | 32.2 | 33.3 | 33.3 | 34.4 |
|
[30.1–35.0] |
[31.1–35.5] |
[30.1–35.5] |
[31.1–36.6] |
GA last visit, week | 35.6 | 35.9 | 35.4 | 36.0 |
|
[34.3–37.0] |
[34.6–37.1] |
[34.0–36.9] |
[34.4–37.1] |
Number of visits | 4.0*** | 3.0 | 5.0*** | 3.0 |
|
[3.0–5.0] |
[3.0–4.0] |
[3.0–6.0] |
[3.0–5.0] |
Insulin treatment, % (n) | 23.3* | 17.4 | 23.6 | 17.4 |
|
(97) |
(75) |
(42) |
(33) |
Insulin initiation, week | 28.1** | 30.6 | 22.2** | 31.1 |
|
[20.6–31.7] |
[27.1–33.6] |
[14.7–29.1] |
[21.3–33.7] |
Long-acting insulin, % (n) | 19.4*** | 10.0 | 20.2** | 9.0 |
|
(81) |
(43) |
(36) |
(17) |
Long-acting insulin – final dose, IU | 12.0 | 14.0 | 14.0 | 16.0 |
|
[8.0–21.0] |
[10.0–26.5] |
[10.0–21.5] |
[12.0–30.0] |
Short-acting insulin, % (n) | 12.5 | 11.9 | 12.9 | 12.7 |
|
(52) |
(51) |
(23) |
(24) |
Short-acting insulin – final dose, IU | 18.0 | 12.0 | 24.0 | 12.0 |
[11.0–30.0] | [9.0–24.0] | [14.0–36.0] | [8.0–25.5] |
Age (years) | 32.6±5.1 | 32.6±5.2 | 32.5±4.9 | 32.0±4.6 |
Pre-pregnancy BMI, kg/m2 | 25.0 [22.1-28.4] | 24.5 [21.6-29.0] | 25.0 [22.1-27.6] | 25.2 [22.1-29.4] |
BMI>30 kg/m2, % (n) | 18.7 (76) | 21.3 (90) | 15.3 (27) | 22.6 (43) |
GWG, kg | 11.0 [8.0-15.0] | 11.0 [7.0-15.0] | 11.0 [7.0-15.0] | 11.0 [7.0-15.0] |
Gestational age at diagnosis (weeks) | ||||
Gestational age at diagnosis (weeks), % (n) | ||||
≤14 | 31.2 (130) | 19.2 (82) | 49.4 (88) | 31.6 (60) |
14–24 | 21.6 (90) | 13.3 (57) | 20.2 (36) | 13.7 (26) |
>24 | 47.2 (197) | 67.5 (289) | 30.3 (54) | 54.7 (104) |
Family history of diabetes, % (n) | 52.7 (214) | 52.0 (222) | 49.1 (86) | 55.8 (106) |
GDM in previous pregnancy, % (n) Parity, % (n) | 29.9 (60) | 28.0 (58) | 35.1 (34) | 32.3 (31) |
Nulliparous | 44.8 (187) | 46.3 (199) | 39.3 (70) | 41.6 (79) |
Multiparous | 55.2 (230) | 53.7 (231) | 60.7 (108) | 58.4 (111) |