<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Post-traumatic osteomyelitis is a common complication of open fractures. Most infections can be resolved by aggressive wound debridement, antibiotics, and normal wound drainage. However, the eradication of infection can be challenging in patients with chronic infection. The pseudarthrosis caused in this way is maintained and difficult to treat even when the infection is cured. Persistent infection may sometimes require suppressive therapy or even limb amputation to control the disease. Improvements in medical treatment have led to increased survivorship and reduced disability in these patients, posing new challenges in their posttraumatic care. This case report describes the use of HBO therapy as an adjunct treatment in a compromised host with recurrent post-traumatic osteomyelitis and refractory pseudarthrosis despite aggressive wound debridement, removal and replacement of the affected bone by autologous bone graft, and several courses of intravenous and oral antibiotic therapy. Hyperbaric oxygen therapy may be considered as an adjunct to standard treatment protocols for refractory osteomyelitis in compromised hosts.</p>
</abstract>

Post-traumatic osteomyelitis is a common complication of open fractures. Most infections can be resolved by aggressive wound debridement, antibiotics, and normal wound drainage. However, the eradication of infection can be challenging in patients with chronic infection. The pseudarthrosis caused in this way is maintained and difficult to treat even when the infection is cured. Persistent infection may sometimes require suppressive therapy or even limb amputation to control the disease. Improvements in medical treatment have led to increased survivorship and reduced disability in these patients, posing new challenges in their posttraumatic care. This case report describes the use of HBO therapy as an adjunct treatment in a compromised host with recurrent post-traumatic osteomyelitis and refractory pseudarthrosis despite aggressive wound debridement, removal and replacement of the affected bone by autologous bone graft, and several courses of intravenous and oral antibiotic therapy. Hyperbaric oxygen therapy may be considered as an adjunct to standard treatment protocols for refractory osteomyelitis in compromised hosts.

Hyperbaric Oxygenation in Treatment of Femoral Pseudoarthrosis Caused by Osteomyelitis

Experimental and Applied Biomedical Research (EABR)

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Post-traumatic osteomyelitis is a common complication of open fractures. Most infections can be resolved by aggressive wound debridement, antibiotics, and...

Hyperbaric Oxygenation in Treatment of Femoral Pseudoarthrosis Caused by Osteomyelitis

Published Online: Apr 05, 2023

Page range: 79 - 83

Received: Nov 04, 2019

Accepted: Feb 10, 2020

DOI: https://doi.org/10.2478/sjecr-2020-0009

Keywords
Post-traumatic osteomyelitis, Pseudarthrosis, Hyperbaric oxygen therapy

© 2023 Gordan Stojanovic, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Hyperbaric Oxygenation in Treatment of Femoral Pseudoarthrosis Caused by Osteomyelitis

Published Online: Apr 05, 2023

Page range: 79 - 83

Received: Nov 04, 2019

Accepted: Feb 10, 2020

DOI: https://doi.org/10.2478/sjecr-2020-0009

KeywordsPost-traumatic osteomyelitis, Pseudarthrosis, Hyperbaric oxygen therapy

© 2023 Gordan Stojanovic, published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
Post-traumatic osteomyelitis, Pseudarthrosis, Hyperbaric oxygen therapy