<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Circulating thyroglobulin measurements is a highly specific test in the management of patients affected by differentiated thyroid cancer after total thyroidectomy, followed by radioiodine ablation. The aim of our study was to compare two thyroglobulinimmunoradiometric assays (INEP, Serbia and Cisbio Bioassays, France). Study included 42 patients of both genders with DTC. The subjects were on suppres¬sive doses of levothyroxine and followed up. Results showed concordance between the two assay methods for determining serum thyroglobulin for 39 (92.85%) patients. Statistical analysis showed that there was a direct correlation between two IRMA tests, with a positive correlation coefficient r=0.613 (p 0.05). We concluded that there is good agreement between the two thyroglobulin assays compared in this study.</p></abstract>

Circulating thyroglobulin measurements is a highly specific test in the management of patients affected by differentiated thyroid cancer after total thyroidectomy, followed by radioiodine ablation. The aim of our study was to compare two thyroglobulinimmunoradiometric assays (INEP, Serbia and Cisbio Bioassays, France). Study included 42 patients of both genders with DTC. The subjects were on suppres¬sive doses of levothyroxine and followed up. Results showed concordance between the two assay methods for determining serum thyroglobulin for 39 (92.85%) patients. Statistical analysis showed that there was a direct correlation between two IRMA tests, with a positive correlation coefficient r=0.613 (p 0.05). We concluded that there is good agreement between the two thyroglobulin assays compared in this study.

Comparison of Thyroglobulin Concentrations Measured by Two Immunoradiometric Assay

Faculty of Medical Sciences, Department of Nuclear medicine

Experimental and Applied Biomedical Research (EABR)

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Circulating thyroglobulin measurements is a highly specific test in the management of patients affected by differentiated thyroid cancer after total...

Comparison of Thyroglobulin Concentrations Measured by Two Immunoradiometric Assay

Published Online: Aug 27, 2020

Page range: 121 - 125

Received: Feb 27, 2018

Accepted: Apr 18, 2018

DOI: https://doi.org/10.2478/sjecr-2018-0031

Keywords
differentitated thyroid carcinoma, thyroglobulin, immunoradiometric assay

© 2020 Vesna Ignjatovic et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Comparison of Thyroglobulin Concentrations Measured by Two Immunoradiometric Assay

Published Online: Aug 27, 2020

Page range: 121 - 125

Received: Feb 27, 2018

Accepted: Apr 18, 2018

DOI: https://doi.org/10.2478/sjecr-2018-0031

Keywordsdifferentitated thyroid carcinoma, thyroglobulin, immunoradiometric assay

© 2020 Vesna Ignjatovic et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
differentitated thyroid carcinoma, thyroglobulin, immunoradiometric assay