<abstract xmlns="http://www.w3.org/1999/xhtml"><p> Reducing food intake can decrease anxiety indices in rats. Th e aim of this study was to evaluate the influence of short-term (48 hours) total food restriction on the behavioural characteristics, the motor coordination and balance, of rats. Th ree-month-old male Wistar albino rats (n=20) weighing 350-400 g were divided into a control group (food and water intake ad libitum) and an experimental group (total food restriction 48 hours before testing). Behavioural studies were performed using the open field, elevated plus maze, Barnes maze, beam walking, evoked beam walking and linear locomotor tests. Th e total distance moved, the velocity, the movement and the frequency in the centre zone of the open field were significantly higher in the treated group. Th e cumulative duration in the centre zone of the open field did not significantly increase in the treated group. Th e number of entries into the open arms, the total time spent in the open arms and the total distance moved in the elevated plus maze significantly increased with no change in the velocity in the food-restricted animals. Th e 48 hours of total food restriction did not affect the Barnes maze test parameters or the parameters of the linear locomotor test. Th e velocity recorded during the beam walking test was not affected by the food restriction, but the velocity recorded during the evoked beam walking test significantly decreased in the treated group. In summary, short-term total food restriction did not produce significant changes in the physical performance of rats but did result in anxiolytic- like behaviour accompanied by food-seeking behaviour due to enhanced motivation to forage for food.</p></abstract>

Reducing food intake can decrease anxiety indices in rats. Th e aim of this study was to evaluate the influence of short-term (48 hours) total food restriction on the behavioural characteristics, the motor coordination and balance, of rats. Th ree-month-old male Wistar albino rats (n=20) weighing 350-400 g were divided into a control group (food and water intake ad libitum) and an experimental group (total food restriction 48 hours before testing). Behavioural studies were performed using the open field, elevated plus maze, Barnes maze, beam walking, evoked beam walking and linear locomotor tests. Th e total distance moved, the velocity, the movement and the frequency in the centre zone of the open field were significantly higher in the treated group. Th e cumulative duration in the centre zone of the open field did not significantly increase in the treated group. Th e number of entries into the open arms, the total time spent in the open arms and the total distance moved in the elevated plus maze significantly increased with no change in the velocity in the food-restricted animals. Th e 48 hours of total food restriction did not affect the Barnes maze test parameters or the parameters of the linear locomotor test. Th e velocity recorded during the beam walking test was not affected by the food restriction, but the velocity recorded during the evoked beam walking test significantly decreased in the treated group. In summary, short-term total food restriction did not produce significant changes in the physical performance of rats but did result in anxiolytic- like behaviour accompanied by food-seeking behaviour due to enhanced motivation to forage for food.

Behavioural Effects of Short-term Total Food Restriction in Rats

Faculty of Medical Sciences, University of Kragujevac, Kragujevac, Serbia

Experimental and Applied Biomedical Research (EABR)

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Behavioural Effects of Short-term Total Food Restriction in Rats"}

Reducing food intake can decrease anxiety indices in rats. Th e aim of this study was to evaluate the influence of short-term (48 hours) total food restriction...

Behavioural Effects of Short-term Total Food Restriction in Rats

Published Online: Oct 10, 2014

Page range: 129 - 137

Received: Aug 14, 2014

Accepted: Aug 31, 2014

DOI: https://doi.org/10.2478/sjecr-2014-0017

Keywords
food restriction, behaviour, anxiety, rat

© 2014

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Behavioural Effects of Short-term Total Food Restriction in Rats

Published Online: Oct 10, 2014

Page range: 129 - 137

Received: Aug 14, 2014

Accepted: Aug 31, 2014

DOI: https://doi.org/10.2478/sjecr-2014-0017

Keywordsfood restriction, behaviour, anxiety, rat

© 2014

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Keywords
food restriction, behaviour, anxiety, rat