<abstract xmlns="http://www.w3.org/1999/xhtml"><bold>Introduction.</bold> Piloleiomyoma is a rare benign tumor which is caused by erector pili muscle and makes up 5% of all leiomyomas. They can be solitary and multiple. Multiple lesions still pose challenges for clinicians since their treatment option is very limited.<bold>Case report.</bold> We report a case of a 25-year-old male patient who had painful papules and nodules on the neck and chest for three years. Multiple red-brown papules and nodules in the skin of regio mammaria dextra and regio submandibularis on the left were seen on physical examination. Histopathological examination of punch bi-were seen on physical examination. Histopathological examination of punch biopsy sample revealed well-circumscribed nodule composed of spindle cells. The case was reported as cutaneous leiomyoma (piloleiomyoma). The patient was given 5 mg/day amlodipin and kept under control.<bold>Conclusion.</bold> The ideal treatment option for piloleiomyoma is surgical excision, but the problem with that treatment is that the lesions have tendency to recur. Medicamentous therapy plays a limited role; however, calcium-channel blockers and <italic>α</italic>-adrenergic blockers may help in palliating or eliminating associated pain through inhibition of smooth muscle contraction.</abstract>

Introduction. Piloleiomyoma is a rare benign tumor which is caused by erector pili muscle and makes up 5% of all leiomyomas. They can be solitary and multiple. Multiple lesions still pose challenges for clinicians since their treatment option is very limited.Case report. We report a case of a 25-year-old male patient who had painful papules and nodules on the neck and chest for three years. Multiple red-brown papules and nodules in the skin of regio mammaria dextra and regio submandibularis on the left were seen on physical examination. Histopathological examination of punch bi-were seen on physical examination. Histopathological examination of punch biopsy sample revealed well-circumscribed nodule composed of spindle cells. The case was reported as cutaneous leiomyoma (piloleiomyoma). The patient was given 5 mg/day amlodipin and kept under control.Conclusion. The ideal treatment option for piloleiomyoma is surgical excision, but the problem with that treatment is that the lesions have tendency to recur. Medicamentous therapy plays a limited role; however, calcium-channel blockers and α-adrenergic blockers may help in palliating or eliminating associated pain through inhibition of smooth muscle contraction.

Piloleiomyoma Presented by Multiple Cutaneous Nodules: a Case Report

Serbian Journal of Dermatology and Venereology

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"Piloleiomyoma Presented by Multiple Cutaneous Nodules: a Case Report"}

Introduction. Piloleiomyoma is a rare benign tumor which is caused by erector pili muscle and makes up 5% of all leiomyomas. They can be solitary and multiple....

Piloleiomyoma Presented by Multiple Cutaneous Nodules: a Case Report

Published Online: Apr 27, 2021

Page range: 157 - 161

Received: Jul 05, 2020

Accepted: Oct 04, 2020

DOI: https://doi.org/10.2478/sjdv-2020-0020

Keywords
Leiomyoma, Skin Neoplasms, Smooth Muscle Tumor, Biopsy, Calcium Channel Blockers, Adrenergic alpha-Antagonists, Rare Diseases

© 2020 Lala Cahangirova et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Piloleiomyoma Presented by Multiple Cutaneous Nodules: a Case Report

Published Online: Apr 27, 2021

Page range: 157 - 161

Received: Jul 05, 2020

Accepted: Oct 04, 2020

DOI: https://doi.org/10.2478/sjdv-2020-0020

KeywordsLeiomyoma, Skin Neoplasms, Smooth Muscle Tumor, Biopsy, Calcium Channel Blockers, Adrenergic alpha-Antagonists, Rare Diseases

© 2020 Lala Cahangirova et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Keywords
Leiomyoma, Skin Neoplasms, Smooth Muscle Tumor, Biopsy, Calcium Channel Blockers, Adrenergic alpha-Antagonists, Rare Diseases